Biology Flashcards
synaptic pruning
degradation and death of axon and dendrite
propionate
protects glia limitans
cysteine
amino acid
glutathione
antioxidant
inflammation
eliminate the initial cause of cell injury, clear out necrotic cells and initiate tissue repair.
Lots of heavy metals
Caused by infections or leaky gut
Leaky gut
Bacterial migration to the brain - sepsis?
weak interaction
decay
standard model
electromagnetic, weak and strong
paracellular diffusion
transfer of substances across an epithelium by passing through the intercellular space
transcellular diffusion
substances travel through the cell, passing through both the apical membrane and basolateral membrane of epithelial cells
norepinephrine
excitatory - hence deficiency causes stereotypy
affinity
think electrons
dihydrofolate reductase function
converts dihydrofolate into tetrahydrofolate, a proton shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids
glutamate in emotions
excitatory effect - controls fear by controlling neuroendocrinology
Gene drive
- CRISPR and ribozymes technologies
- in the second generation, the whole drive copies itself onto its partner chromosome through CRISPR cuts
- 100% of offspring
Oxitec - Friendly Mosquitoes
- genetically edited tTAV gene
- prevents gene expression
- binds to tetO operators, positive feedback loop
- inhibited by tetracycline - can’t be found in the wild
Stereotactic envenimation
- GABA - inhibitory
- β-alanine - anti-anxiety: increases brain-derived neurotrophic factor (mediator of anxiety)
- taurine - stimulates GABA
Educational neuroscience
- neural architects
- multisensory teaching for neuroplasticity
- increased functional processing between temporal gyrus and amygdala
- manipulation for reward