Biological Treatment of SZ Flashcards

1
Q

what was an early treatment for sz

A

a prefrontal lobotomy

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2
Q

anti-psychotics were designed to do what

A

to help a person manage their disorder, but also help manage their life too

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3
Q

what treatment is usually recommended as an initial treatment for sz and why

A

drug treatments as they can offer some immediate relief

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4
Q

how can anti-psychotics be taken

A

syrup tablet or injection

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5
Q

how does the whole process of the drug treatment for sz work

A
  • doctor prescribes
  • monitors for side effects
  • adjust quantity / type of drug so it is tailored to the person
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6
Q

how to antipsychotics work

A

they block the dopamine receptors which lowers the activity at the synapse which reduces positive symptoms

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7
Q

what are the two types of anti-psychotics

A

typical and atypical

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8
Q

describe typical drugs

A

blocks dopamine receptors lowering activity reducing mainly positive symptoms

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9
Q

describe atypical drugs

A

block dopamine less/more temporarily and also block other nt like serotonin can reduce both positive and negative symptoms

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10
Q

what are the side effects of typical antipsychotics

A

tardive dyskinesia (abnormal movement of facial muscles), spasm, low blood pressure

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11
Q

side effects of atypical drugs

A

similar side effects, less common, less severe (e.g.tardive dyskinesia 5.4% with typical vs 0.8% with atypical)

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12
Q

what did leiberman find (drug treatment for sz)

A

:( he found many of the ps stopped taking meds due to the severe side effects
this conflicts that it is a successful treatment for sz as there may be better tratment without the side effects

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13
Q

what did rosa find (drug treatment for sz)

A

:( found only 50% of ps complied with taking meds therefor is less useful if patient is reluctant to take the treatment

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14
Q

what did emsley find (drug treatment for sz)

A

:) emsley found 84% of patients on anti-psychotics had at least a 50% reduction in symptoms -> anti-psychotics help symptoms so they are an effective treatment of sz

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15
Q

what did hogarty find (drug treatment for sz)

A

:) found that relapse rate 48% taking anti-psychotic vs 80% without medication therefore effective treatment for sz as less patients symptoms are returning

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16
Q

weaknesses of drug treatment for sz (4)

A

:( drug treatments are not treating the cause just alleviate the symptoms
:( no empirical way to test if the drug is working can only ask the patient who may lie
:( not effective for everyone as not tailored to individual
:( side effects may leave a patient to discontinue the medication