biological explanation of sz other than nt NC

Question 1

what is the biological explanation of sz other than nt

Answer 1

genetics

Question 2

genetic explanation of sz : concordance rate

Answer 2

dz twins 17%, mz twins 48% -> therefor must be genetic to an extent as mz twins share 100% of genes
OTOH must be other factors or it would be 100% for mz twins

Question 3

genetic explanation of sz : C4-A gene

Answer 3

certain variations of this gene are associated with an increased risk of sz

Question 4

genetic explanation of sz : COMT gene

Answer 4

depletion of this is associated with dopamine level control -> may lead to excess dopamine

Question 5

genetic explanation of sz : sensitivity

Answer 5

altered sensitivity to some chemicals -> may become more sensitive to dopamine which leads to developing sz

Question 6

genetic explanation of sz : neural pathways

Answer 6

genes can cause neural pathways in brain to be disrupted or damaged -> behaviour does not develop properly

Question 7

genetic explanation of sz : chromosomes

Answer 7

several chromosomes are associated with an increased risk of sz 22,18,15
chromosome 22 causes DiGeorge syndrome where 1 in 4 people develop sz

Question 8

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