Biological Molecules : Digestion Flashcards
Carbohydrate digestion : salivary amylase (substrate)
Starch
Carbohydrate digestion : salivary amylase (product)
Maltose
Carbohydrate digestion : salivary amylase (how’s it made)
Salivary gland
Carbohydrate digestion : salivary amylase (acts?)
Mouth
Carbohydrate digestion : salivary amylase (breaks which bond)
Alpha 1-4 glycosidic
Carbohydrate digestion : pancreatic amylase (substrate)
Starch
Carbohydrate digestion : pancreatic amylase (product)
Maltose
Carbohydrate digestion : pancreatic amylase (made?)
Pancreas
Carbohydrate digestion : pancreatic amylase (acts?)
Ileum
Carbohydrate digestion : pancreatic amylase (break bond)
Alpha 1-4 glycosidic bonds
Carbohydrate digestion : maltase (substrate)
Maltose
Carbohydrate digestion : maltase (product)
Alpha glucose x2
Carbohydrate digestion : maltase (made?)
Lining of ileum
Carbohydrate digestion : maltase (acts?)
I’m ileum
Carbohydrate digestion : maltase (breaks bond)
Alpha 1-4 glycosidic bond
Carbohydrate digestion : lactase (substrate)
Lactose
Carbohydrate digestion : lactase (product)
Alpha glucose + galactose
Carbohydrate digestion : lactase (made)
Lining of ileum
Carbohydrate digestion : lactase (acts)
Ileum
Carbohydrate digestion : sucrase (substrate)
Sucrose
Carbohydrate digestion : sucrase (product)
Alpha glucose + fructose
Carbohydrate digestion : sucrase (Made?)
Lining of ileum
What is digestion ?
Hydrolysis of large insoluble food molecules into smaller soluble food molecules
What are the 3 membrane bound disaccharidases
- Maltase
- lactase
- sucrase
Chemical digestion: how is chemical digestion carried out ?
Carried out by enzymes via hydrolysis
Chemical digestion: What is hydrolysis
Splitting of molecules by adding water to chemical bonds
Carbohydrates hydrolyse …
Carbohydrates to monosaharides
Lipases hydrolyse ….
Lipids into glycerol and fatty acids
Pro teases hydrolyse …
Proteins into amino acids
Lipid digestion : What happens prior to enzyme action ?
Process called emulsification
Lipid digestion : What does emulsification do ?
- Increases s.a of lipids so action of lipases is sped up
- faster hydrolysis for Ester bonds
Lipid digestion : What are lipids split into ?
Micelles by bile salts in liver
Lipid digestion : lipase (substrate)
Triglycerides
Lipid digestion : lipase (Product)
Monogyleceride + 2 fatty acids
Lipid digestion : lipase (Made?)
- pancreas
- lining of ileum
Lipid digestion : lipase (Acts?)
Ileum
Lipid digestion : lipase (Bond broken)
Ester bond
Protein digestion : What group are proteins hydrolysed by ?
Group of enzymes called peptidases
Protein digestion : 3 different peptidases
- endopeptidases
- exopeptidases
- dipeptidases
Protein digestion : Endopeptidase (substrate)
Polypeptides
Protein digestion : Endopeptidase (Product)
Smaller peptides
Protein digestion : Endopeptidase (Made?)
- stomach
- pancreas
Protein digestion : Endopeptidase (Acts?)
-stomach
Ileum
Protein digestion : Endopeptidase (Bond broken)
Peptide bond
Protein digestion : Exopeptidase (substrate)
- smaller peptides
- polypeptides
Protein digestion : Exopeptidase (Product)
- amino acids
- dipeptides
Protein digestion : Exopeptidase (Acts)
- stomach
- ileum
Protein digestion : Exopeptidase (Made)
- stomach
- pancreas
Protein digestion : Exopeptidase (Bond broken)
- peptide bond
Protein digestion : dipeptidase (substrate)
Dipeptide
Protein digestion : dipeptidase (Product)
Amino acids
Protein digestion : dipeptidase (Made?)
Lining of ileum
Protein digestion : dipeptidase (Acts?)
Ileum
Protein digestion : dipeptidase (Bond broken)
Peptide bond
Adaptations of ileum : Inner wall folded into villi
increases s.a for absorption
Adaptations of ileum : One cell thick
Decreases diffusion distance
Adaptations of ileum : Many capillaries
Maintains diffusion gradient
Adaptations of ileum : Epithelial cells have microvilli
Increases s.a for absorption
Adaptations of ileum : what are microvilli
Folds within their membrane
Adaptations of ileum : Epithelial cells have lots of mitochondria
Increase active transport
Absorption of glucose / amino acids : step 1
Step 1 = sodium ions are actively transported from the epithelial cell into blood by carrier proteins
Absorption of glucose / amino acids : step 2
Lowers the concentration of sodium in cell relative to blood and lumen
Absorption of glucose / amino acids : step 3 + 4
- Sodium enters epithelial cell via a carrier proteins with a glucose molecule via facilitated diffusion
- glucose enters blood via f.d
Absorption of glucose / amino acids : step 5
Sodium travels down a concentration gradient whereas glucose travels up
Absorption of lipids : fat digestion order
- triglycerides
- smaller droplets of triglycerides
- monoglycerides + 2 fatty acids
- micells
Absorption of lipids:when the Micelle breaks down at the epithelial cell , what is released ?
Monoglycerides and fatty acids
Absorption of lipids: why do monoglycerides and fatty acids diffuse
Noon-polar molecules
Absorption of lipids: Why do the micelles need to be digested before entering cell?
So they can diffuse through cell
Absorption of lipids: Once inside the cell where are mg and f.a transported
- endoplasmic reticulum where they reform into triglyceride
Absorption of lipids: After e.r ?
Transported to Golgi apparatus = associate with cholesterol and lipoproteins to produce chylomicrons
Absorption of lipids: What are chylomicrons ?
Special particles adapted for the transport of lipids
Absorption of lipids: How do chylomicrons move out of cell ?
Exocytosis
Absorption of lipids: After exocytosis where do chylomicrons enter ?
Capillaries called lacteals at centre of each villus