Bioenergetics Flashcards
What is bioenergetics?
Flow of energy in a biological system: macronutrients into biologically useable energy. (food/chemical energy into muscle contraction/mechanical energy)
Exergonic vs. endergonic reactions
Exergonic: releases energy; usually catabolic
Endergonic: requires energy; usually endergonic
3 basic biological energy systems
1) phosphagen
2) glycolysis
3) oxidative systems
Anaerobic process
Do not require the presence of oxygen
Aerobic process
Process that depends on oxygen
Kreb cycle, electron transport chain, and rest of the oxidative system
Aerobic mechanisms that occur in the mitochondria
Which macronutrients are essential to anaerobic metabolism and why?
Carbohydrates: metabolized for energy with out oxygen involvement
Creatine phosphate
High energy molecule involved in the phosphagen system. Hydrolysis of this molecule provides a phosphate group to combine with ADP
Law of mass action or mass action effect
The concentration of reactants and/ or products in solution will drive the direction of the reaction
Glycolysis
The break down of carbohydrates; anaerobic. Less rapid than creatine kinase but higher capacity of ATP
What 2 things can happen with pyruvate?
1) fast glycolysis: converted to lactate and used for anaerobic ATP resynthesis
2) taken to mitochondria and undergoes the keen cycle (slower and used for longer duration)
Gluconeogenesis
The formation of glucose from noncarbohydrate sources- during extended exercise and recovery
true or false: the process of pyruvate to lactate results in the formation of lactic acid.
False.
lactate production increases with…
increased exercise and type II muscle fibers
Lactate clearance
3 ways: lactate can be oxidized in the muscle it was produced in or transported by the blood to another muscle to be oxidized OR taken to liver where it is converted into glucose
Cori Cycle
cycle of: blood glucose taken to the muscle- lactate in muscle- blood transports lactate to liver - converted to glucose in the liver- taken back by way of the blood to muscle
Phosphorylation
process of adding an inorganic phosphate to another molecule. (ADP+P=ATP)
Oxidative Phosphorylation
resynthesis of ATP in the electron transport chain
Substrate Level Phosphorylation
direct resynthesis of ATP from ADP during a single reaction in the metabolic pathways.
What are the 2 primary mechanisms for ATP resynthesis during metabolism
Substrate-level phosphorylation and
Oxidative phosphorylation
What is the net gain of glycolysis (using blood glucose)? Explain
2 ATP are required to power glycolysis and 4 are resynthesized: net gain of 2
What is the net gain of glycolysis (using muscle glycogen)? Explain
1 ATP is required to power glycolysis and 4 are resunthesized: net gain of 3
What factors stimulate glycolysis?
High concentrations of ADP, decrease in pH levels and AMP