Biochemistry Flashcards
intermediate in fructose metabolism
glyceraldehyde
found in blood and cartilage tissue
erythrose
present in cells particularly in the mitochondria; sugar in RNA
ribose
main source of fuel in cells
glucose
can enter glycolysis and produce intermediates for cellular respiration
fructose
simple sugars
monosaccharide
naturally occurring sugars
D-sugars
the OH and C=O can undergo intramolecular cyclization to form __
hemiacetals
aldohexoses typically form a six-membered ring or a __
pyranose ring
monosaccharides that cannot be converted into smaller molecules by hydrolysis
simple carbohydrates
made of two or more simple sugars (oligo- and polysaccharides) linked together by glycosidic bonds
complex carbohydrates
composed of 2 to 10 monosaccharides
oligosaccharides
bond that joins the monosaccharides in oligo- and polysaccharides
glycosidic linkage
glucose + fructose
sucrose (table sugar)
galactose + glucose
lactose (milk sugar)
glucose + glucose
maltose (malt sugar)
contain three or more monosaccharides linked together
polysaccharides
two groups of polysaccharides
homopolysaccharides and heteropolysaccharides
a polymer composed of repeating glucose units joined by alpha-glyosidic linkages
starch
formed from glucose units with alpha-1,4-glycosidic bonds
amylose
formed from glucose units but with branching due to alpha-1,6-glycosidic bonds
amylopectin
found in the cell walls of nearly all plants (most abundant), where it gives support and rigidity to wood and plant stems
cellulose
an unbranched polymer composed of glucose joined in a beta-1,4-glycosidic linkage; water insoluble
cellulose
extensively branched glucose polymer that animals use as an energy reserve
glycogen
molecule that has both polar (hydrophilic) and nonpolar (hydrophobic) parts
amphipath or amphiphile
simplest hydrolyzable lipids, they are esters formed from a fatty acid and high molecular weight alcohol
waxes
most abundant lipids
triacylglycerols or triglycerides (aka fats and oils)
basic hydrolysis of TAGs producing glycerol and soaps
saponification
saturated C10-C20 fatty acids
Capric, Lauric, Myristic, Palmitic, Stearic, Arachidic
composed of saturated FA; solid at room temp
animal fats
composed of unsaturated FA; liquid at room temp
vegetable oils
lengthens the shelf life of fats and oils by reducing the unsaturation (C=C) via catalytic addition of hydrogen
hydrogenation
second most abundant type of lipid; form the principal lipid component of most cell membranes
phosphoacylglycerols (phosphoglycerides)
derived from sphingosine; component of the lipid bilayer of cell membranes
sphingomyelins
the coating that surrounds and insulates nerve cells, is rich in sphingomyelins
myelin sheath
nonpolar amino acids (alkyl group)
alanine (A), valine (V), leucine (L), isoleucine (I)
acidic amino acids
aspartic acid (D), glutamic acid (E), asparagine (N), glutamine (Q)
OH or S amino acids
serine (S), threonine (T), cysteine (C), methionine (M)
basic amino acids
histidine (H), lysine (K), arginine (R)
aromatic amino acids
phenylalanine (F), tyrosine (Y), tryptophan (W)
essential amino acids
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arginine
non essential amino acids
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way a polypeptide folds in a repeating arrangement to form alpha-helices and beta-pleated sheets
secondary structure
structural protein of connective tissues where it provides strength and elasticity; most abundant protein in humans
collagen
made possible by the primary structure of collagen
extended helix structure
resemble long ribbons or fibers
fibrous proteins
relatively spherical of ovoid in shape
globular proteins
established the 3D structure of DNA
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sugar + base
nucleoside
sugar + base + phosphate
nucleotide
redox reactions involving substrates
oxidoreductases
transfer of functional groups between two substrates
transferases
hydrolysis by the addition of water
hydrolases
addition of a group to a double bond or elimination of a group to create a double bond without hydrolysis
lyases
transfer of groups within substrates to yield isomeric forms
isomerases
formation of bonds by condensation reactions couples to cleavage of ATP or similar cofactor
ligases
movement of ions or molecules across membranes or their separation within membranes
translocases
breaks down carbs and starches into simple sugars
amylase
breaks down lactose into simple sugars glucose and galactose
lactase
breaks down lipids into fatty acids and glycerol
lipase
breaks down protein into amino acids
protease
breaks down malt sugar into glucose
maltase
breaks down sugar into glucose and fructose
sucrase
involved in digesting long protein chains into shorter fragments by splitting the peptide bonds that link amino acid residues
proteases
detach the terminal amino acids from the protein chain
exopeptidases
attack internal peptide bonds of a protein
endopeptidases
lower the activation energy; very specific as to what substrates they bind and the chemical reaction they catalyze
enzymes
substrate binding occurs in a pocket on the enzyme called __
active site
suggest that the substrate possess specific complementary geometric shapes that fit exactly into the enzyme
lock and key model