Biochemistry

Question 1

What does the Golgi apparatus do?

Answer 1

Modifies, sorts, and packages these molecules that are destined for cell secretion
The addition of mannose-6-phosphate to proteins designates transport to lysosome

Question 2

What does Mitochondrion do?

Answer 2

Aerobic respiration. Contains mitochondrial genome as circular DNA

Question 3

What does the Nucleus do?

Answer 3

DNA maintenance
RNA transcription
RNA splicing
the process that removes the intervening, non-coding sequences of genes (introns) from pre-mRNA and joins the protein-coding sequences (exons)

Question 4

What is the most important investigation that should be done for hypercalcaemia at a high level?

Answer 4

They should have an ECG due to risk of dysrhythmia

Question 5

What are the two commenest causes of hypercalcaemia?

Answer 5

• Primary hyperparathyroidism
• Cancer

Question 6

If IV NaCl does not reduce calcium what do you use as second line?

Answer 6

IV Bisphosphonates such as Zolendronic acid