Biochem Module 6 Flashcards

0
Q
The ff amino acids are polar uncharged except 
A. Cysteine 
B. Threonine
C. Asparagine 
D. Lysine
A

D.
Polar uncharged- CAST PG
Cysteine, asparagine (N) , serine, threonine, proline, glutamine (Q)

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1
Q
Co factors needed to convert serine to glycine except 
A. Pyrodixal phosphate 
B. Tetrahydrofolate 
C. FADH2 
D. Nota
A

C

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4
Q
Classified as imino acid 
A. Lysine 
B. Threonine 
C. Proline 
D. Isoleucine
A

C

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5
Q
Our genetic code can encode \_\_\_\_\_amino acid 
A. 19 
B. 20 
C. 21
D. 22
A

B

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8
Q
Serine will be cleaved by 
A. Pepsin 
B. Elastase 
C. Chymotrypsin 
D. Secretin
A

B

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10
Q
Adults synthesize arginine thru 
A. Krebs cycle 
B. Urea cycle 
C. Gluconeogenesis 
D. Cori cycle
A

B

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11
Q
Secondary messenger utilized by insulin 
A. cAMP
B. cGMP 
C. Tyrosine kinase 
D. IP3
A

C

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12
Q
Which of the ff is most lipophobic 
A. Asparagine 
B. Glycine 
C. Tyrosine 
D. Methionine
A

A

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13
Q
What amino terminal speeds up  ubiquination 
A. Glutamine 
B. Phenylalanine 
C. Serine 
D. Arginine
A

D. With aspartate

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14
Q
Amino acids that are synthesized from essential amino acid except 
A. Cysteine 
B. Tyrosine 
C. Alanine 
D. Hydroxylysine
A

C

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15
Q
The  amino acid that came from  alpha ketoglutarate 
A. Arginine 
B. Leucine 
C. Cysteine 
D. Serine
A

A.
Alpha ketoglutarate - PreREQuisite
proline (p), arginine (r), Glutamate (e), glutamine (q),

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16
Q
Amino acid from oxaloacetate 
A. Lysine 
B. Tyrosine 
C. Tryptophan 
D. Glycine
A

A.
Oxaloacetate- DoN’T MaKe
Aspartate (D), aspRagine (n), threonine, methionine, lysine (k)

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18
Q
Role of tetrahydrofolate in the conversion of serine and glycine 
A. Amino donor 
B. Methyl donor 
C. Oxygen donor 
D. Hydrogen donor
A

B

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19
Q
Amino acid that can be derived from pyruvate 
A. Valine 
B. Isoleucine 
C. Leu cine 
D. Alanine 
E. Aota
A

E

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20
Q
Deficiency of enzyme homogentisate oxidase
A. Phenylketonuria 
B. Alkaptonuria 
C. Hartnup disease 
D. Maple syrup urine disease
A

B

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21
Q
Where does urea cycle occur 
A. Muscle 
B. Kidney 
C. Liver 
D. Brain
A

C

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22
Q
Serine can be derived from 
A. Pyruvate 
B. 3 phosphoglycerate 
C. Oxaloacetate 
D. Phosphoenolpyruvate
A

B. Along with glycine and cysteine

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23
Q
Cofactor needed in the conversion of phenylalanine to tyrosine 
A. Tetrahydrobiopterin 
B. Pyridoxal phosphate 
C. SAM 
D. NADH
A

A.

Enzyme: phenylalanine hydroxylase

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26
Q
More than 30 miniutes of running, the body will start breaking down proteins. Which amino acid will be broken down first 
A. Histidine
B. Arginine 
C. Lysine 
D. Isoleucine
A

D. BrAnched amino acid

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27
Q

4 stages of urea biosynthesis
A. Trans amination, glutamine oxidation, ammonia transport, urea cycle reactions
B. Trans amination, glutamine reduction, ammonia transport, urea cycle reactions
C. Trans amination, glutamine oxidation, urea transport, urea cycle reactions
D. Trans amination, glutamine reduction , urea transport, urea cycle reactions

A

A

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28
Q
Metabolic precursor of the aromatic amino acid except histidine 
A. Pyruvate 
B. Alpha ketoglutarate 
C. Oxaloacetate 
D. Phosphoenolpyruvate
A

D

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29
Q
This part of the cell surface receptor that generates secondary messenger 
A. Extracellular domain 
B. Transmembrane domain 
C. Cytoplasmic domain 
D. Nuclear domain
A

C

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30
Q
Organisms that excrete nontoxic, water-soluble urea are called
A. Ammonotelic 
B. Uricotelic 
C. Ureteric 
D. Ureotelic
A

D

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31
Q
Glucocorticoid can induce breakdown of what AA 
A. Histidine 
B. Cysteine 
C. Phenylalanine 
D. Tryptophan
A

D

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32
Q
Where are housekeeping enzymes degraded 
A. Mitochondria 
B. Cytosol 
C. Lysosomes 
D. Nucleus
A

C. ATP non required

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33
Q
Which of the ff repels water molecule STRONGLY 
A. Cysteine 
B. Proline
C. Serine 
D. Glutamic acid
A

A

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34
Q
Intracellular receptor part that stimulates transcription 
A. DNA binding domain 
B. Amino binding domain 
C. Cytoplasmic binding domain 
D. Carboxyl binding domain
A

B

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35
Q
Absence of ketoacid dehydrogenase complex 
A. Phenylketonuria 
B. Alkaptonuria 
C. Hartnup disease 
D. Maple syrup urine disease
A

D

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36
Q
Transferring of an amino group from glutamate will yield 
A. Alpha ketoglutarate
B. Oxaloacetate 
C. Pyruvate 
D. Nota
A

A

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37
Q
Termination codon that encodes for selocysteine 
A. UAG 
B. UAA
C. UGA 
D. UAU
A

C

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38
Q
Removal of alpha-amino nitrogen by transaminationis the first catabolic reaction, EXCEPT for the following amino acids
A. Proline 
B. Cysteine 
C. Threonine 
D. Lysine
A

B

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39
Q
Purely Ketogenic amino acid 
A. Glutamate 
B. Methionine  
C. Leucine 
D. Histidine
A

C

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40
Q
This amino acid is needed in the formation of sphingosine 
A. Tryptophan 
B. Threonine 
C. Histidine 
D. Serine
A

D

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41
Q
Which amino acid forms FIGLU as intermediate when broken down 
A. Leu cine 
B. Alanine 
C. Phenylalanine 
D. Histidine
A

D

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42
Q
Tyrosine's conversion to homogentisate need what cofactor to act as reductant 
A. Tetrahydrofolate 
B. Pyridoxal phosphate 
C. Ascorbate 
D. Glutamate
A

C

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43
Q
Tyrosine may be synthesized from what amino acid 
A. Leu cine 
B. Methionine 
C. Phenylalanine 
D. Glutamate
A

C

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44
Q
The ff are positively charged amino acid except 
A. Histidine 
B. Aspartic acid 
C. Lysine 
D. Arginine
A

B
Polar, positively charged - HaRK
Histidine, arginine (r), lysine (k)

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46
Q
Which of the ff is least lipophobic 
A. Isoleucine 
B. Glutamic acid 
C. Alanine 
D. Arginine
A

B. Least lipophobic, most hydrophilic.

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47
Q
Amino acid source of proline 
A. Glutamine 
B. Glutamate 
C. Aspartate 
D. Asparagine
A

B

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53
Q
Amino acid precursor of melatonin 
A. Tyrosine 
B. Tryptophan 
C. Arginine
D. Alanine
A

B. Serotonin din

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56
Q
In purine synthesis, N9 is from 
A. Glycine 
B. Glutamine 
C. Aspartate 
D. Histidine
A

B

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57
Q
Milk production is the action of 
A. Dopamine 
B. Oxytocin
C. ADH 
D. Prolactin
A

D

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58
Q
Which of the ff is the most lipophilic 
A. Arginine 
B. Lysine 
C. Phenylalanine 
D. Methionine
A

C. Most hydrophobic, most lipophilic

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59
Q
For hormones to communicate with its target tissues, it must travel thru 
A. Muscles 
B. Blood 
C. Water 
D. Neurotransmitter
A

B

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60
Q
Phenylalanine will be cleaved by 
A. Pepsin 
B. Elastase 
C. Chymotrypsin 
D. Secretin
A

C

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64
Q
Which of the ff plays a role in pain perception 
A. ACTH 
B. MSH
C. Endorphins 
D. TSH
A

C

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66
Q
Which of the ff is the most hydrophobic 
A. Leucine 
B. Histidine 
C. Serine 
D. Cysteine
A

A.

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73
Q
Amino acid that is synthesized when pyrimidine is broken down 
A. Glutamine 
B. Cysteine 
C. Alanine 
D. Methionine
A

C

74
Q
Most of the thyroid hormone is bound to 
A. Thyroxine binding protein 
B. Thyroxine binding albumin 
C. Thyroxine binding pre albumin 
D. ALbumin
A

A

76
Q
The ff are aromatic amino acids except 
A. Threonine 
B. Tryptophan 
C. Tyrosine 
D. Phenylalanine
A

A
Aromatic - WHiFY
Tryptophan (W), histidine, phenylalanine (F), tyrosine (Y)

77
Q
Precursor of nitric oxide 
A. Glutamine 
B. Asparagine 
C. Histidine 
D. Arginine
A

D

78
Q
Glycoprotein's activity is seeni n the 
A. Alpha subunit 
B. Beta subunit
C. Delta subunit 
D. Omega subunit
A

B

79
Q
The ff are essential amino acids except 
A. Threonine 
B. Methionine 
C. Tryptophan 
D. Serine
A

D.
PRiVaTe TIM HALL always arginine never tyrosine
Phenylalanine, Valine, threonine, tryptophan, isoleucine, methionine, histidine, arginine, leu cine, lysine

80
Q
What AA is converted to propionyl coA before conversion to Succinyl coA 
A. Lysine  
B. Methionine 
C. Aspartate 
D. Isoleucine
A

D

81
Q
Reaction of Ornithine to putrescince 
A. Oxidation 
B. Reduction 
C. Methylation 
D. Carboxylation
A

D

82
Q
Valine is converted to what before it becomes succinyl coA 
A. Acetyl coA 
B. Propionyl coA 
C. Methyl malonyl coA 
D. Choline
A

C

83
Q
Amino acid catabolism forming TCA intermediates except 
A. Alanine 
B. Phenylalanine 
C. Asparagine 
D. Arginine
A

A. Forms pyruvate

84
Q
Intracellular receptor part that binds with the hormone 
A. DNA binding domain 
B. Amino binding domain 
C. Cytoplasmic binding domain 
D. Carboxyl binding domain
A

D

85
Q
What aa catabolism yields biotin as one of its product 
A. Leucine 
B. Methionine 
C. Histidine 
D. Valine
A

A

86
Q
Predominant pathway for lysine degradation 
A. Saccharopine  formation 
B. kynurenine anthranilate pathway
C. Cori cycle 
D. TCA
A

A

B. - for tryptophan

88
Q
The ff displays negative nitrogen balance except 
A. MarAsmus kid 
B. Pregnant mother 
C. Father with advance cancer 
D. Post - op patient
A

B

89
Q
Arginine will be cleaved by 
A. Trypsin  
B. Elastase 
C. Chymotrypsin 
D. Secretin
A

A

90
Q
Excessive amounts of GH before epiphyseal closure of the long bones leads to
A. Dwarfism 
B. Acromegaly 
C. Gigantism 
D. Pygmie
A

Gigantism

91
Q
Which of the ff can cleave an internal bond between amino acids  
A. Carboxypeptidase 
B. Aminopeptidase 
C. Lipase 
D. Trypsin
A

D. Endopeptidase

92
Q
In the conversion of dopamine to norepinephrine , what co factor is needed 
A. Pyridoxal phosphate 
B. Ascorbate 
C. SAM
D. Tetrabiopterin
A

B. With copper

93
Q

PEST sequence target protein for rapid degradation. Which of the ff contains the sequence
A. Phenylalanine, glutamate, serine, tyrosine
B. Phenylalanine, aspartate, serine, threonine
C. Proline, glutamate, serine, threonine
D. Proline, aspartate, serine, tyrosine

A

C

94
Q
In purine synthesis, N3 is from 
A. Glycine 
B. Glutamine 
C. Aspartate 
D. Histidine
A

B

95
Q
Where is GNRH1 encoded 
A. Chromosome 4
B. Chromosome 8
C. Chromosome 12
D. Chromosome 16
A

Ph

96
Q
Where are abnormal proteins degraded 
A. Mitochondria 
B. Cytosol 
C. Lysosomes 
D. Nucleus
A

B. Requires ATP and ubiquitin

97
Q
In the conversion of dopa to dopamine, what co factor is needed 
A. Pyridoxal phosphate 
B. Ascorbate 
C. SAM
D. Tetrabiopterin
A

A

98
Q

True or false. Marasmus will exhibit a protruding abdomen like in kwashiorkor

A

False.

99
Q
During transamination, bound \_\_\_\_\_\_\_ serves as a carrier of amino groups
A. Glutamine 
B. Biotin 
C. Pyridoxal phosphate 
D. Tetrahydrofolate
A

C

100
Q
In tissues, ammonia is converted to 
A. Aspartate 
B. Glutamine 
C. Histidine 
D. Methionine
A

B

101
Q
What amino terminal retards ubiquination 
A. Glutamine 
B. Phenylalanine 
C. Serine 
D. Arginine
A

C. Also methionine

102
Q
Aquatic animals that are compelled to excrete water waster continuously are called 
A. Ammonotelic
B. Uricotelic 
C. Ureteric
D. Ureoteric
A

A

103
Q
Ubiquitin acts by forming non-peptide bonds between the carboxyl terminal of ubiquitin and the  amino groups of \_\_\_\_\_\_ residues in the target protein
A. Arginine 
B. Ornithine 
C. Proline 
D. Lysine
A

D

104
Q
Sugar part of FSH that is critical for its half life 
A. Fructose
B. Sialic acid 
C. Galactose 
D. Glucosamine
A

B

105
Q
AA which is part of the compound that is the principal source of methyl groups in the body
A. Methionine 
B. Cysteine 
C. Leucine 
D. Glutamate
A

A

106
Q
Uricotelic organism must conserve water, so they excrete Uric acid as 
A. Adeno 
B. Guano
C. Cysto
D. Purino
A

B

107
Q
Inhibitor of liver GDH except 
A. ATP 
B. GTP 
C. ADP
D. NADH
A

C. Stimulates

108
Q
the only amino acid that undergoes oxidative deamination at an appreciable rate in mammalian tissues
A. Serine
B. Alanine 
C. Glutamate 
D. Aspartate
A

C

109
Q
Ammonia is toxic to the brain because it interferes with the 
A. Glycolysis 
B. Gluconeogenesis 
C. TCA 
D. Lipogenesis
A

C

111
Q
Contributes in the formation of spermine 
A. Isoleucine 
B. Threonine 
C. Valine 
D. Methionine
A

D

112
Q
In the conversion of norepinephrine  to epinephrine , what co factor is needed 
A. Pyridoxal phosphate 
B. Ascorbate 
C. SAM
D. Tetrabiopterin
A

C

113
Q
Tryptophan is involved in the synthesis of 
A. Norepinephrine 
B. Acetylcholine 
C. Serotonin 
D. Dopamine
A

C

114
Q
The only hormone that can promote the translocation of calcium against the concentration gradient which exists across the intestinal cell membrane
A. PTH 
B. T3
C. Vitamin D 
E. FSH
A

C

115
Q
The ff are precursors of creatine phosphate except 
A. Glycine 
B. Phenylalanine 
C. Arginine 
D. Methionine
A

B

116
Q
In purine synthesis, N7 is from 
A. Glycine 
B. Glutamine 
C. Aspartate 
D. Histidine
A

A

117
Q
Amino acid derived from ribose 5 phosphate 
A. Histidine 
B. Phenylalanine 
C. Tyrosine 
D. Ornithine
A

A

118
Q
Co enzyme A needs what amino acid 
A. Glycine 
B. Arginine 
C. Alanine 
D. Serine
A

C

119
Q
Cyclic AMP is a nucleotide generated from ATP through the action of 
A. ADP 
B. Adenylate cyclase 
C. Phosphodiesterase 
D. Nitric oxide
A

B

120
Q

Posterior pituitary gland secretes what hormones

A

ADH, oxytocin

122
Q

Carbamoyl phosphate synthase I uses how many ATP

A

2

124
Q
Secondary messenger used by nitric oxide 
A. cAMP
B. cGMP 
C. Tyrosine kinase 
D. IP3
A

B

125
Q
The ff characterizes  hormones made of protein 
A. Long half life 
B. Does not need a secondary messenger 
C. Does not need a transport protein 
D. Receptor seen in the cytosol
A

C

126
Q
Amino acid precursor of histamine
A. Tyrosine 
B. Tryptophan 
C. Arginine
D. Glutamic acid
A

D

127
Q
In purine synthesis, N1 is from 
A. Glycine 
B. Glutamine 
C. Aspartate 
D. Histidine
A

C

128
Q
Process by which glycolytic intermediates become amino acid 
A. Carboxylation 
B. Trans amination 
C. Redox reaction 
D. Phosphorylation
A

B

129
Q
Hormone that seems to determine the duration of pregnancy
A. Somatocrinin
B. Somatostatin 
C. Corticotropin releasing hormone 
D. ACTH
A

C

130
Q

Mechanism of action of ADH
A. Adenylyl cyclase activation leading to insertion of Aquaporins
B. CGMP utilization leading to vasodilation
C. Sympathetic nervous system stimulation leading to increase in urine output
D. IP3 mediated release of calcium leading to contraction of Sphincters

A

A

131
Q
What complex can activates phospholipase 
A. G protein - GDP complex 
B. G protein - ADP complex 
C. G protein- GTP complex 
D. G protein- ATP complex
A

C

132
Q
Carbamoyl phosphate synthase I is the rate limiting enzyme of 
A. TCA 
B. Lipogenesis 
C. Urea cycle 
D. Cholesterol synthesis
A

C

133
Q
This can inhibit growth hormone 
A. Carbohydrates 
B. Proteins
C. Estradiol
D, exercise
A

A

134
Q
Decrease vasopressin release leads to 
A. Insulin dependent diabetes mellitus 
B. Non insulin dependent diabetes mellitus 
C. Polydipsia 
D. Diabetes insipidus
A

D

135
Q
Carbamoyl phosphate synthase I is activated by 
A. N acetyl glutamate 
B. Biopterin 
C. SAM 
D. ATP
A

A

136
Q
Conversion of T4 to T3 is inhibited by 
A. PTU 
B. Epinephrine 
C. Insulin 
D. Activin
A

A

137
Q
The detection of the \_\_\_\_\_  has become useful for people who want to know when ovulation occurs
A. FSH surge 
B. LH surge 
C. ACTH surge 
D. Thyrotrophin surge
A

B

138
Q
Thyrotropin-releasing factor (TRF), thyroliberin or protirelin stimulates the release of TSH and 
A. ADH 
B. GH
C. CCK 
D. Prolactin
A

D

140
Q
What hormone is involved in social recognition and bonding
A. ADH 
B. Oxytocin 
C. FSH 
D. LH
A

B

141
Q
Thyroid hormones require \_\_\_\_\_ for its biological activity 
A. Iodine 
B. Sodium 
C. Potassium 
D. Oxygen
A

A

142
Q
protein is also responsible for the transport of retinol - transthyretin
A. Thyroxine binding protein 
B. Thyroxine binding albumin 
C. Thyroxine binding pre albumin 
D. ALbumin
A

C

143
Q
T3 are found by combining MIT and DIT thru the process of 
A. Organification 
B. Calcification
C. Coupling 
D. Oxidative decarboxylation
A

C

144
Q
The ff amino acids are non polar except 
A. Histidine 
B. Leucine 
C. Alanine 
D. Methionine
A

A.
Non polar - G. VILMA
Glycine, valine, isoleucine, methionine, alanine

161
Q
Controls the release of pituitary hormones in a pulsatile manner
A. Medulla 
B. Cranial nerves 
C. Frontal lobe 
D. Hypothalamus
A

D

162
Q
Calcium and phosphate homeostasis is primarily under the control of
A. T4 
B. Calcitonin 
C. Parathyroid 
D. ACTH
A

C

163
Q
Source of amino group in the synthesis of glutamate 
A.NH4+ 
B. Histidine 
C. Glutamine 
D. Dead animals
A

C

164
Q
Source of amino group in the synthesis of glutamine 
A.NH4+ 
B. Histidine 
C. Glutamine 
D. Dead animals
A

A

165
Q
Trans amination of glycine to glyoxylate may be done with the help of 
A. Alanine 
B. Valine 
C. Threonine 
D. Phenylalanine
A

A or glutamate…