Bio Chapter 5 Flashcards
What does it mean for phospholipids to be amphipathic molecules?
The tail is hydrophobic - fears water, 2 fatty acid chains that are nonpolar
The head is hydrophilic - loves water, glycerol molecule and a phosphate group that is polar
Phospholipids - saturated and unsaturated
Carbons are saturated with H, only single bond
Carbons are unsaturated when at least on C=C double bond is present
Phospholipids
Most abundant lipid in plasma membrane
Will automatically arrange themselves in a bilayer with the polar heads facing outward and the hydrophobic tails are inward
Permeability of lipid bilayer
Controlled by the plasma membrane
Hydrophobic molecules can dissolve in lipid bilayer and pass through membrane rapidly
Hydrophilic molecules do not cross membrane easily
Diffusion
Tendency for molecules to spread out evenly
Passive transport
Movement across a membrane with no energy investment
Diffusion vs. Osmosis
Diffusion is small uncharged molecules (O2 and CO2)
Osmosis is the diffusion of water
Osmosis
Diffusion of water across selectively permeable membrane
From a region of lower solute concentration to higher solute concentration
Hypotonic
Concentration outside cell is less than inside
Hypertonic
Concentration outside cell is greater than inside
Isotonic
Concentration is same inside and outside cell
Active transport
Uses energy to move solutes against their gradients
Primary active transport
ATP provides energy
Secondary active transport
Electrochemical gradient provides energy
Membrane potential
Voltage across a membrane
Cytoplasmic side carries negative charge compared to extracellular side
Sodium potassium pump
Move in opposite directions
If they bring 3 in then 2 must go out
Uses energy from ATP hydrolysis
ATP
3 phosphate
ADP
2 phosphates
AMP
1 phosphate
Endocytosis
Cells takes in macromolecules
Pinocytosis
Soluble materials are taken up from environment and incorporated into vesicles for digestion (little sips)
Phagocytosis
Uptake of larger particles
Once engulfed, turns into phagosome, then fuses with lysosome to break down contents
Exocytosis
Releasing through vesicle outside the cell
Receptor mediated endocytosis
Receptor in membrane that mediates process of endocytosis
Specific solutes bind to receptors triggering vesicle formation