Biliary Secretion Flashcards
1
Q
functions of the liver
A
- bile production and secretion
- metabolism of carbs, proteins, lipids
- bilirubin production and excretion
- detoxification of substances
2
Q
metabolic functions of the liver: carbs
A
glucose storage as glycogen
gluconeogenesis
release of glucose
3
Q
metabolic functions of liver: proteins
A
- albumin and clotting factors (liver failure leads to hypoalbuminemia which may lead to edema)
- synthesis of nonessential amino acids
- modication of amino acids for use in biosyn pathways for carbs
- conversion of ammonia to urea
4
Q
metabolic functions of liver: lipids
A
- fatty acid oxidation
- synthesis of lipoproteins, cholesterol, phospholipids
5
Q
what makes up bile?
A
bile salts 50% phospholipids 40% (lecithin) cholesterol 4 % bile pigments (billirubin) 2 % ions H2O
6
Q
primary bile acids and which one is the most soluble
A
cholic acid and chenodeoxycholic acid
cholic acid is most soluble bc it has the most OH groups on it
7
Q
secondary bile acids and least soluble
A
deoxycholic acid and lithocholic acid
lithocholic acid is least soluble
8
Q
what are bile acids conjugated with and what is the reason
A
conjugated with taurine and glycine to make them more water soluble
9
Q
predominant cation and anions in bile
A
Na+
Cl- and HCO3-
