Benign Skin Lesions Flashcards
What are milia?
small epidermoid cysts that are filled with keratin
Where do you find milia?
cheeks, eyelids, forehead, and genitals
Who gets milia?
- infants
- all ages (sun damaged skin)
How do you treat milia?
May resolve spontaneously or can be easily removed with blade or needle
What is a dermatofibroma?
benign fibrotic tumor of the skin that is firm, hyperpigmented, and dome-shaped with a peripheral rim of darkening pigment
Where do you commonly find dermatofibromas?
often found on extremities (possibly due to trauma)
How can you diagnose a dermatofibroma?
“dimple sign”–when you pinch on either side of it, it will dimple due to the scar-like tethering of the dermis
Multiple dermatofibromas may be associated with what disease?
systmic diseases like LUPUS
How do you treat a dermatofibroma?
stable and asymptomatic so they do NOT require treatment
What does a seborrheic keratosis look like?
lesions have “stuck-on quality” like a piece of wax pressed to the skin)—also gently picking at lesion will cause it to crumble, lift, or flake off
WILL NOT SEE HAIRS GROWING OUT OF IT
What do you see under dermoscopy when you are looking at seborrheic keratosis?
keratin pseudocytes (small white spots within lesion)
Seborrheic keratosis is associated with activating mutations in which gene?
FGFR-3
How do you treat a seborrheic keratosis?
they are benign, so you just leave them alone
Acute onset of multiple seborrheic keratosis is called what? What might it mean?
Sign of Leser-Trelat: associated with malignancy (adenocarcinoma in GI tract, breast and lung)
When would you biopsy a seborrheic keratosis?
-“ugly duckling” lesion
