Benign and premalignant skin conditions Flashcards

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1
Q

What are the types of benign skin lesion?

A
Seborrhoeic keratosis
Viral warts
Cysts
Dermatofibroma
Lipoma
VAscular lesions
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2
Q

What are the clinical features of seborrhoeic keratosis?

A

Warty growth, stuck on appearance, but can be variable

Patient may have multiple cherry adenomas

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3
Q

What is the treatment of seborrhoea keratosis?

A

Can be left untreated but if troublesome

  • cryotherapy with liquid nitrogen
  • curettage
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4
Q

What is Leser-Trelat?

A

Paraneoplastic phenomenon- abrupt onset of widespread seborrhoea keratosis, particularly in younger individual

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5
Q

What does Leser Trelat indicate?

A

Possible underlying malignancy e.g. GI adenocarcinoma

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6
Q

What causes viral warts?

A

HPV

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7
Q

What is the appearance of viral warts?

A

Rough hyperkeratotic surface

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8
Q

What is the treatment of viral warts?

A

Cryotherapy or wart paints

Curettage in severe cases

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9
Q

When do viral warts clear?

A

When immunity is developed to HPV

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10
Q

What are cysts?

A

Encapsulated lesion containing fluid or semi fluid material
Usually firm and fluctuant
Can rupture and cause inflammation of surrounding skin or become affected

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11
Q

What are the types of cyst?

A
Epidermoid cyst
Pilar cyst
Steatocystoma
Dermoid cyst
Hidrocystoma
Ganglion cyst
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12
Q

What is the treatment of a cyst?

A

Excision

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13
Q

What is the treatment of an infected/inflamed cyst?

A

Antibiotics
Intralesional steroid
Incision and drainage

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14
Q

What ar the clinical features of a dermatofibroma?

A

Benign fibrous nodule, often on limbs
Firn nodule tethered to skin but mobile over fat
Pale pink/brown. often [aler in centre
Dimple sign positive
Usually asymptomatic but may be itchy or tender

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15
Q

What are dermatofibromas caused by?

A

Proliferation of fibroblasts

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16
Q

What is the treatment of a dermatofibroma?

A

Excision if concerning or symptomatic

17
Q

What is a lipoma?

A

Benign tumour consisting of fat cells- smooth and rubbery subcutaneous mass that can be tender

18
Q

What types of lipoma are the der?

A

Angiolipoma

Liposarcoma

19
Q

What are the types of benign vascular lesions?

A

ANgioma

Pyogenic granuloma

20
Q

What is an angioma?

A

Pregnancy

Liver diseaseOvergrowth of blood vessels in the skin due to proliferating endothelial cells

21
Q

What are the clinical features of an angioma?What are the risk factors for an angioma?

A

Generally asymptomatic but may be unsightly or bleed

22
Q

What is the treatment of angiomas?

A

Excision

Laser

23
Q

What is a pyogenic granuloma?

A

Rapidly enlarging red/raw growth, often at site of trauma

24
Q

What are the clinical features of a pyogenic granuloma?

A

Bleed easily
Common on head and hands
Common in pregnancy

25
Q

What is the treatment of pyogenic granulomas?

A

Curettage and cautery

26
Q

What are the risk factors for pre malignancy skin lesions to become malignant?

A

UV radiation

Immunosuppression

27
Q

What are the types pf premalignant skin lesions?

A

Actinic keratosis
Bowen’s disease
Melanoma in situ

28
Q

What are the clinical features of actinic keratosis?

A

Rough, scaly patches on sun damaged skin
Low risk of progression to SCC
Common and may spontaneously resolve

29
Q

What is the treatment of actinic keratosis?

A

Cryotherapy
Curettage
Diclofenal gel
Imiquimod

30
Q

What is Bowen’s disease?

A

Irregular, scaly erythematous plaque with full thickness dysplasia, entirely comtaioin in epidermis

31
Q

What is the likelihood of malignant progression with Bowen’s disease?

A

5%

32
Q

What is the treatment of Bowen’s disease?

A

Cryotherapy
Curettage
Photodynamic therapy
Imiquimod

33
Q

What is a melanoma in situ?

A

Melanoma cells entirely confine din epidermis with no metastatic potential

34
Q

What is the treatment of melanoma in situ?

A

EXcision

35
Q

What is imiquimod?

A

Immune response modifier

36
Q

What is lentigo maligna?

A

Type of melanoma in situ, usually facial