behavioural genetics 1 Flashcards

1
Q

what is heritability?

A
  • an estimate of how much variance in some characteristic within some population is due to differences in heredity
  • varies between 0 and 1
    –> i.e. 0 and 100%
  • 0.5 intermediate
  • not related to individual differences due to genes
  • variation in ENTIRE POPULATION due to genes
  • lower heritability suggests other factors that cause variance
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2
Q

the use of twins

A
  • behavioural genetics mainly look at twin studies
  • like to compare MZ and DZ twins
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3
Q

heritability in MZ twins

A
  • all traits are in and around 50%
    –> about 50% due to genes and about 50% due to environment
  • positive correlations
  • not 100%
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4
Q

MZ twin predictions

A
  • we can see how similar pairs of twins are for a particular trait
  • if a trait was completely heritable the twin pairs would score exactly the same as one another
    –> in MZ twins who share 100% of genes
  • MZ twins tend to have positive correlations
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5
Q

the use of DZ twins

A
  • fraternal twins
  • non-identical
  • shared 50% of genes
    –> same has any other full siblings
  • 2 eggs
  • can compare to MZ twin results
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6
Q

problem with using anecdotal studies

A
  • subjective
  • can spot similarities by chance accidentally
  • can spot differences by chance accidentally
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7
Q

problems with just studying identical twins (solution?)

A
  • in modern studies it is unlikely that the twins were reared a part
  • therefore they share an environment
  • solution = compare MZ twins with DZ twins
    –> likely to both share environments
    –> therefore variance can be due to genes
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8
Q

heritability of psychological disorders

A
  • higher heritability in MZ twins for most disorders
    –> e.g. schizophrenia and childhood fatigue
    –> likely to have genetic influence
  • higher correlation coefficient links to genes
  • DIFFERENCE between DZ and MZ links to genes
  • similarities in MZ and DZ link to influence of environment
    –> e.g. bulimia is relatively low and similar for DZ and MZ twins
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9
Q

how do we calculate heritability using behavioural genetics?

A
  • heritability is calculated by comparing the correlation coefficients of identical and non-identical twins for a particular trait
  • we know that identical twins share all their genetic variation
  • we know that non-identical twins share 50% of their genetic variation
  • heritability is twice the difference between the correlations for identical minus non-identical twins
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10
Q

formula for variance

A

Vp= A squared + C squared + E squared

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11
Q

what do the letters in the heritability formula stand for?

A
  • V is the variance of a trait
  • A is the genetic component
  • C is the common or “shared” environment
    –> anything in environment that makes traits similar across twin pairs
  • E is the “non-shared” environment
    –> anything in the environment that makes the traits dissimilar across twin pairs
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12
Q

formula for MZ correlation coefficient

A

Rmz = A squared + C squared

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13
Q

formula for DZ correlation coefficient

A

Rdz = 1/2 A squared + C squared

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14
Q

easy formula for a heritability (A squared)

A
  • A squared = 2 x (Rmz - Rdz)
  • heritability is twice the difference between the correlations for identical minus non-identical twins
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15
Q

slight issues with behavioural genetics

A
  • heritability is ‘specific’ to the population in which it is calculated
  • it looks at variance (differences) between individuals
  • high heritability does not imply the environment doesn’t alter that trait
  • particularly for the individual
  • it can change over time?
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16
Q

heritability and the environment

A
  • high heritability does NOT imply that environment does NOT play a role
  • you can have 100% heritability in plants but create different environments and if plants grow differently, environment will be playing a role
  • if you didn’t have 2 plants with 100% heritability, you might think it’s due to genes, when really it’s due to the environment
17
Q

heritability and cognitive ability

A
  • heritability of general cognitive ability increases linearly from childhood to young adulthood
    –> in the same cohort of twins
  • could be due to environments
    –> i.e. similarities in people from the same geographical are (or more variance)
    –> or due to the multiplier effects
18
Q

complexities with heritability: multiplier effect

A
  • if Genetic or prenatal influences produce even a small increase in some activity, the early tendency will change the environment in a way that magnifies that tendency
  • i.e. people who think they’re good at something do more things to get better, hence they change the environment
    –> genetic predisposition is therefore multiplied by the environmental/behavioural changes
19
Q

complexities with heritability: tobacco example

A
  • heritability estimate of 65%
  • far fewer people smoke tobacco in modern times than they did in the 90s
  • but heritability estimate is still 65%
    –> how can it be genetic then?
    –> clearly environment has played a role
    –> unlikely for genes to change
20
Q

summarise behavioural genetics and heritability

A
  • heritability is an estimate of how much variance in some characteristic within some population is due to differences in heredity
  • varies between 0 and 1 (i.e. 0 and 100%)
  • it is calculated by comparing the correlations or concordances of identical and non-identical twins
  • it is specific to the population in which it is calculated
  • it can ‘change’ over time