BCSE (Zuku Review + Merk Veterinary Manual) Flashcards

1
Q

A Thoroughbred colt is presented with warm, firm, painful swellings over bilateral distal medial forelimbs. The colt has a stiff gait. No history of trauma. What is the most likely diagnosis?

A

Physitis.

A common developmental orthopaedic disease. Is an inflammation and swelling around the growth plates (physes) of the long bones. It is It is especially common in large, rapidly growing young horses, especially when the ground is hard. Additional risk factors include abnormal calcium-to-phosphorous ratio, too much exercise, obesity, conformational defects, and toxicosis. Most common bones affected (in order): distal radius, distal tibia, distal third metatarsal or metacarpal bones, and proximal first phalanx.

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2
Q

Most appropriate site for placement an intraosseous catheter in birds?

A

The distal ULNA is the site most frequently utilized for placement of an intraosseous catheter in birds. The proximal tibiotarsal bone is another site often used.

The humerus and femur are pneumatic bones and would deliver fluids into the respiratory tract.

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3
Q

Which female has ovaries that look like grape clusters because of the large number of follicles?

A

Sow. Sows have 10-20 follicles ready for fertilization every estrus cycle.

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4
Q

What is initially recommended for horses who suffer from uncomplicated intermittent delayed release of the patella from its position over the medial trochlear ridge of the femur?

A

Controlled exercise program first recommendation, it helps strengthen the quadriceps (and biceps femoris) muscles of the thigh and therefore removal of the patella from its “locked” position over the medial trochlear ridge.

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5
Q

Structure of skeletal myocyte

A

Skeletal muscle is made up of bundles of myocytes that appear circular (viewed in cross section). The myocytes can be distinguished by their circular cross sections, well-delineated cell junctions, and peripheral nuclei.

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6
Q

Which condition of cattle involves thickening of the skin between the claws of the feet?

A

Interdigital hyperplasia or fibroma is a thickening of the skin between the claws of the cow’s foot. More common in the rear feet. Usually secondary to chronic irritation (trauma or infection)

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7
Q

In racing horses which condition occurs in the dorsoproximal fetlock joint? This problem presents with lameness, fetlock joint effusion, firm swelling over the does-proximal fetlock joint, and a positive response to firm flexión of the fetlock.

A

Villonodular synovitis. Common condition in Thoroughbred race horses that presents with lameness, fetlock joint effusion, firm swelling over the dorsoproximal fetlock joint, and positive response to firm flexión of the fetlock. Proliferative synovitis characterized by enlargement of the fibrocartilaginous pad on the dorsoproximal aspect of the joint where the joint capsule attaches. It’s likely due to repetitive trauma form expertise.

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8
Q

Traumatic poll injury (rearing over backward) often results in rupture of which muscle in the horse?

A

Longus Capties Muscle. One of the ventral straight muscles of the head, inserts on the basisphenoid bone at the base of the skull. With traumatic poll injury, rupture occurs at the insertion of the muscle dorsal to the guttural pouch and results in severe hemorrhage. Bleeding from the guttural pouch neurologic deficits, and death can occur.

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9
Q

What is the treatment for angular limb deformity in foals?

A

Mild cases of angular limb deformity will improve without treatment. Mild cases may correct on their own.

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10
Q

What is the ossa cordis and in which animals do you see it / them?

A

Heart bones. Presented in cattle and older horses. Skeleton of the heart, made up f the connective tissue that separates the atria from the ventricles (like a floor). It provides attachment points for the heart valves and contains two bones, the ossa cordis. Seen in cattle, older horses.

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11
Q

Functional unit of kidney?

A

The nephron is the functional unit of the kidney and is composed of the glomerulus, renal tubule, and capillaries. Bowman’s capsule surrounds the nephron

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12
Q

A stray cat is presented that is acting strangely and lashing out aggressively at any movement. The animal appears hungry and thirsty, yet is unable to swallow properly and rabies is suspected. Which two cranial nerves are needed to coordinate swallowing?

A

Glossopharyngeal nerve (CN 9), Vagus nerve (CN 10).

Think of the glossopharyngeal nerve (and vagus) in association with motor damage to pharynx and swallowing. The classic disease associated with pharyngeal paralysis is rabies.

Think of damage to the recurrent laryngeal nerve (a branch of the vagus) in association with motor damage to larynx and vocalization. The classic disease associated with laryngeal paralysis is laryngeal hemiplegia (“roaring” in horses).

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13
Q

Abortions due to brucellosis tend to occur at what stage of pregnancy?

A

Last half of pregnancy.

Typically, brucellosis causes abortion in the last half of pregnancy, from the 5th month onwards.

Expect stillborn calves. Cows only abort once, then they are immune.

Brucellosis is a reportable disease.

The vaccines used are the Brucella abortus strain 19 vaccine or the RB51 vaccine, given to heifer calves 4-12 months old, along with a USDA tattoo in the right ear.

Trichomoniasis typically causes early abortion in cows and neosporosis typically causes mid-term abortion, but most diseases cause abortion late (3rd trimester) or have variable timing.

The common abortion timelines are guidelines only - they help with boards questions but it’s not always so cut and dry in practice.

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14
Q

Which pair of neonatal calf diarrheas both have public health/zoonotic significance?

A

Cryptosporidiosis, salmonella.

Cryptosporidiosis is caused by a protozoa implicated in drinking water-associated outbreaks of diarrhea in humans. Salmonellae can infect humans from a number of different sources (turtles, chickens, eggs).

E. coli can cause human disease, but Ostertagia and bovine rotavirus do not. (There IS a human version of rotavirus, however)

C. perfringens can be found in soil and in the normal gut flora and is not contagious.
Eimeria spp. (the causative agent of coccidiosis) are host-specific. Therefore, cattle Eimeria spp. cannot infect humans, sheep, etc.

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15
Q

What is true regarding bovine leukosis virus?

A

Most infected animals have no outward clinical signs.

The most common outcome of infection with Bovine leukosis virus (BLV) is persistent infection with no outward clinical signs or lymphocytosis.
About a 1/3 of infected cattle develop a persistent benign lymphocytosis and <5% develop lymphosarcoma.

BLV infection is more common in dairy cattle than in beef cattle.

BLV is not a zoonosis. There is no treatment.

Risk is minimized by preventing the transfer of blood (and therefore infected lymphocytes) between cattle. Vertical transmission can also occur.

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16
Q

A four-year-old Saanen goat is presented that is off feed and feverish, with a swollen and draining abscess associated with her left prescapular lymph node. Caseous lymphadenitis (CLE) is suspected. What is the causative organism?

A

Corynebacterium pseudotuberculosis.

Remember your “C’s” - caseous lymphadenitis (CL) is caused by Corynebacterium pseudotuberculosis. Potentially ZOONOTIC, so wear gloves if you clean/debride an open abscess in a sheep or goat. REPORTABLE in some states (e.g., Georgia, Michigan).

Pretty common, and like contagious ecthyma (orf), CL is one of those diseases you watch out for when doing health exams for animals going to a fair.

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17
Q

The owner of a recently acquired small goat dairy plans to castrate the one-week-old goat kids. The vaccination history of the herd is unknown. What vaccinations/treatments should be given at the time of castration?

A

Clostridium perfringens C,D; tetanus toxoid; tetanus antitoxin

Since the vaccination history is unknown, the kids should be vaccinated with Clostridium perfringens C and D and tetanus toxoid and provide immediate protection with tetanus antitoxin.

If the does were definitely vaccinated, then no vaccines would be needed at the time of castration. C. perfringens C and D and tetanus toxoid are instead given to kids at one to two months of age and again one month later.

Orf and footrot vaccines are not core vaccines in goats. The orf vaccine is a live vaccine and should only be used if the disease has been diagnosed in the herd. The footrot vaccine is approved for sheep but only serves to reduce the number and severity of cases.

Continue with other management procedures such as quarantine, hoof trimming, and
footbaths.

Caseous lymphadenitis (Corynebacterium pseudotuberculosis) does have a vaccine, but there is no vaccine available for caprine arthritis and encephalitis (CAE).

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18
Q

Burkholderia mallei, a highly contagious disease of equids is characterized by ulcerative nodules of the skin and upper respiratory tract. What is the common name of this reportable disease?

A

Glanders.

Glanders, caused by Burkholderia mallei, is a highly contagious, often fatal disease of equids characterized by high fever, thick mucopurulent nasal discharge, ulcerative nodules of the skin and upper respiratory tract.

Humans, felids, and other animals are also susceptible. This disease is now exotic to the USA.

Trypanosoma equiperdium is the cause of dourine, a chronic venereal disease of horses recognized in Africa, the Middle East, and South America.

Theileria parva is an important tickborne hemoparasitic cause of disease in cattle in central and eastern Africa known as East Coast Fever.

Clinical signs of the disease include high fever, lymphadenopathy, dyspnea, and death.

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19
Q

Prior to administration, what is the best way to determine the milk/meat withdrawal time of a medication for a food animal?

A

Consult the Food Animal Residue Avoidance Databank

The most up-to-date guidelines on withdrawal times in food-producing animals are available from the Food Animal Residue Avoidance Databank (FARAD).

There are strict withdrawal regulations because drug residues in the food chain could b harmful to humans.

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20
Q

After the first rabies vaccination, when is a dog (or cat or ferret) considered to be fully immunized and protected against rabies?

A

After 28 days.

According to the 2016 Compendium for Rabies Control, a peak rabies virus antibody titer is reached 28 days after initial vaccination and immediately after booster vaccination.

Here are some things to remember about rabies:
When in doubt, it is never wrong to check with your local health department.

Basicallv all potential rabies exposures boil down to 2 questions:
1. Who is involved?
Animal-animal exposure (less alarm bells)
Animal bites/exposed human (more alarm bells)
2. Was dog/cat/ferret vaccinated?
Documented up to date on rabies vaccination (booster + 45 days owner observation)
Documented vaccinated, but overdue (booster + 45 days owner observation)
UN-documented vaccinated, and overdue (handle on case-by-case basis)
Ferrets that are OVERDUE for booster (handle on case-by-case basis)
UN-vaccinated pet (euthanize or vaccinate + 4-6 month strict isolation)
Wild animal, esp. bats, raccoon, skunk (euthanize, send head to state lab)
When dealing with rabies questions, ask yourself if this seems like a HIGH-risk exposure (e.g., wild raccoon bites a child) or a LOWER risk exposure (e.g., up-to-date vaccinated dog messes with woodchuck but no bite wounds on dog).

For high-risk lean towards euthanasia/testing or immediate vaccination + long, strict isolation (4 months, dogs/cats, 6 months, ferrets).

For low-risk lean towards immediate vaccination + shorter, easier observation period (45 days).

In general, both Canadian and U.S. guidance on rabies post exposure management conforms with Compendium guidelines.

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21
Q

What is the most effective treatment for feline aggression?

A

Selective serotonin reuptake inhibitors

Selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants combined with desensitization and counter conditioning exercises are the most effective way to manage feline aggression.

Aversive stimuli like reprimands and punishment are ineffective and counterproductive.

Offering reassurance or reward for an aggressive act may enhance aggressive learned behavior.

Anxiolytics such as buspirone or benzodiazepines may decrease patient inhibition and therefore INCREASE aggression. Oral diazepam carries the risk of fatal hepatotoxicity.

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22
Q

What part of an anesthetic circuit absorbs carbon dioxide?

A

Soda lime canister.

A canister of soda lime granules in the anesthetic circuit absorbs carbon dioxide (COz)
from exhaled anesthetic gasses.

Fresh absorbent crystals are white and can be crushed. But exhausted, saturated crystals become a distinct off-white color and are hard.

Most granules contain a pH-sensitive dye that becomes visible as the absorbent granules become saturated. A color change from white to purple or violet typically indicates that the COz absorbent granules are saturated with CO2, but this color change does not always happen and it may dissipate after a few hours.

The veterinary anesthesia and analgesia support group is a good resource for anesthesia information.

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23
Q

When might epidural anesthesia be contraindicated in a cow with distocia?

A

When planning virginal delivery.

Epidural anesthesia can be contraindicated in cases where vaginal delivery is the planned method of delivery because it means the cow will not be able to assist in delivering the calf.

Epidural anesthesia helps minimize the pain caused by vaginal manipulation of a dystocia. However, sometimes the cow will become recumbent, which can be contraindicated when trying to pull a calf.

It also reduces the force of uterine contractions so manipulation is easier to accomplish.

24
Q

Why should reptiles be kept at the upper limit of their normal temperature range during induction, surgery and anesthetic recovery?

A

Optimizes anesthetic metabolism and recovery.

Reptiles have a preferred optimal temperature range (POT) for optimal uptake, action, transformation and excretion of premedication sedatives and maintenance anesthetics.

Lower temperatures slow a reptile’s metabolism which in turn slows the eliminätion of drugs out of the body and delays recovery from anesthesia or sedation.

25
Q

A 15-year-old horse is presented for chronic right forelimb lameness. Exam reveals a grade 3/5 lameness on the AAEP lameness scale ((0/5 is sound, 5/5 is non-weight bearing) and mild sensitivity to hoof testers over the medial toe. Radiographs of the foot reveal the following. What is the most distal nerve block that is likely to improve this horse’s lameness?

Photo

A

Abaxial

An abaxial nerve block is the most distal nerve blood that would alleviate this horse’s lameness; it usually desensitizes the entire foot.

The palmar digital nerve block typically anesthetizes the heel portion (palmar/plantar ½) of the foot. The other nerve blocks listed are higher up the leg and would work, but are not necessary. In practice nerve blocks are not an exact science but these are good rules of thumb.

There is a circular radiolucency visible at the solar margin of the third (distal) phalanx, consistent with a keratoma. This radiographic view is called a “65° dorsoproximal-palmarodistal oblique” or “solar margin view” because it highlights the solar margin of the third phalanx.

Keratomas are benign masses that develop at the coronary band and grow down between the third phalanx and hoof wall. They cause lameness and radiolucency and must be removed surgically via hoof wall resection.

Ref: Ross and Dyson, Diagnosis and Management of Lameness in the Horse, pp. 358-59.
Images courtesy of Nora Grenager, VMD, DACVIM.

26
Q

What is the correct fresh gas flow rate for anesthetic maintenance using a semi - closed rebreathing circuit?

A

20-40 mL / kg / min

Set the fresh gas flow rate during anesthetic maintenance at 20-40 mL/kg/min with a semi-closed (a.k.a. partial rebreathing) circuit. This is the most common anesthetic breathing system used in small animal practice. Use a non-rebreathing circuit for patients weighing <2-2.5 kg.

The fresh gas flow rate is set higher than the animal’s metabolic demand (> 10mL/kg/min) and waste gasses exit through the partially open pop-off valve. In semi-closed and closed breathing circuits COz is absorbed by the CO2 absorbent canister so expired gasses are safe to rebreathe.

In non-rebreathing circuits the oxygen flow rate is relatively high because expired gasses are flushed out of the system.

Here is some additional useful information about anesthetic equipment.

27
Q

If inhalant anesthetic agents A and B are compared, which property would result in the quickest induction, recovery, and changes in depth of anesthesia?

A

Low blood-gas partition coefficient.

Inhalant anesthetic agents with a low blood-gas partition coefficient have higher speeds of induction, recovery, and changes in depth of anesthesia. Sevoflurane and isoflurane are examples of inhalant agents with low blood -gas partition coefficients. Sevoflurane is less soluble than isoflurane leading to more rapid induction and recovery with this agent.
Solubility determines the speed of anesthetic induction and recovery; therefore induction and recovery is slower with halothane than with sevoflurane or isoflurane. A gas with a very high solubility such as ether has an even slower induction and recovery.
Desflurane, with its extremely low solubility, has the fastest induction and recovery, but is not typically used in veterinary medicine.
Neither sevoflurane nor isoflurane provide any analgesia after recovery, and their minimum alveolar concentration (MAC) is a measure of the potency of the agent. The higher the MAC, the less potent the drug.

28
Q

Salivation stops in most animals under inhalant general anesthesia. Which one of the following animals CONTINUES to salivate regardless of the drugs used?

A

Bovine

Ruminants and camelids continue to salivate under sedation or anesthesia, even when anti-cholinergics are given.
This is why it is important to intubate ruminants and camelids during inhalant anesthesia and to position the nose down so that the saliva can drain away from the pharynx.
These species also regurgitate rumen fluid under anesthesia, especially during light or deep anesthesia, so be aware of this possibility.
Regurgitation can be active or passive; it is active when they are light and esophageal contractions occur. It is generally passive when they are very relaxed and adequately anesthetized.
For more, see Anesthetic Monitoring by Lyon Lee DVM, PhD.

29
Q

Post-anesthetic apnea commonly occurs with protocol. What piece of monitoring equipment is used to measure carbon dioxide levels to ensure ventilation efforts are not excessive?

A

Capnograph

We use a capnograph to monitor carbon dioxide (i.e., end-tidal COz) levels.
Pulse oximeters measure oxygen saturation of RBCs, and an ECG measures cardiac electrical conduction. An esophageal stethoscope is used to more directly monitor cardiac pulses during anesthesia.

Additional monitoring during anesthesia may include invasive and noninvasive blood pressure monitoring, thermometers, and measurements of respiratory rate and volume.

30
Q

Which of the following correctly describes the phenomenon of allodynia?

A

Stimuli that are not normally painful produce a pain response.

Allodynia is pain produced by stimuli that are not normally painful.

Hyperalgesia is an exaggerated response to a painful stimuli. Hypoalgesia is a decreased response to a painful stimuli. Tolerance is a decreased analgesic effect: seen with use of pain medication.

Both hyperalgesia and allodynia develop with severe acute pain and with chronic pain where the components of pain pathways become sensitized to painful and eventually non-painful stimuli.

Low-threshold sensory nerve fibers are believed to be involved in the development of both hyperalgesia and allodynia.

Following excessive stimulation from numerous sources, the response patterns of A-delta and C fiber pain receptors gradually change.

Also, A-beta fibers, which normally respond only to innocuous stimuli such as touch, begin responding to painful input.

See the Taxonomy of Pain from the International Association for the Study of Pain, Pain Management Guidelines for Dogs & Cats from the Am. Animal Hospital Assoc, and the Veterinary Anesthesia and Analgesia Support Group.

31
Q

A seven-week-old female domestic shorthair kitten weighing 1.5 kg is presented for an enucleation (removal of the eye). When should food be withheld prior to anesthesia?

A

1-2 hours before induction.

Due to their small size and lack of glucose stores, young animals less than 2 kg should not be fasted longer than 2 hours prior to anesthesia. It is not necessary to withhold water in neonates and doing so may cause dehydration.
Before anesthesia, routine fasting can help prevent regurgitation of food into the esophagus or mouth and aspiration into the lungs. Regurgitation can also lead to esophageal strictures due to the high acidity of gastric fluid.
The American Animal Hospital Association provides these fasting guidelines for dogs and cats.

32
Q

Which anatomic structures pass through the guttural pouch in horses, and may be affected by diseases within (like mycosis or empyema)?

A

Cranial nerves 9,10; internal carotid artery.

Cranial nerves 9 through 12, the internal and external carotid artery, maxillary artery, and cranial cervical ganglion pass through/are within the guttural pouch.
Cranial nerves 7 and 8 are closely associated but not truly within the pouch.
Clinical signs of guttural pouch disease reflect dysfunction of these critical structures: dysphagia, Horner syndrome, vestibular signs, unilateral facial nerve paralysis.
Key guttural pouch conditions to remember include:
- guttural pouch tympany
- guttural pouch empyema
- guttural pouch mycosis
Follow this link to see an endoscopic view of GP mycosis: note the white fungal plaque over the internal carotid artery and cranial nerves 9 (glossopharyngeal) and 10 (vagus)
along the caudodorsal wall of the medial compartment.

33
Q

These bones (blue arrows) are fused in ruminants and horses but not in carnivores (like this dog). What does this difference allow carnivores to do?

A

Rotate the forearm.

The ulna is fused with the radius in ruminants and horses, which prevents them from supinating or pronating the forearm.
They are not fused in carnivores and pigs, so these animals can pronate and supinate the forearm (rotate it).
Image courtesy of Kirill Tsukanov.

34
Q

Which of the following structures is marked with the yellow circle?

A

Seminiferous tubule.

The entire structure outlined in yellow is a seminiferous tubule of a tesus, where spermatogensis occurs. #1 is the lumen of the tubule.

Leydig cells (#7, also called interstitial cells) are located in the intersitium between the seminiferous tubules.
The Leydig cells produce most of the body’s testosterone in response to luteinizing hormone secreted from the pituitary.

Sertoli cells are indicated by #5. These are also called ‘nurse” cells because they produce hormones and proteins to facilitate spermatogenesis.

Images courtesy of original Testiclular histology, boar image (Uwe Gille).

The Gonads and Tubular Genital Tract in Animals.
https://www.merckvetmanual.com/reproductive-system/reproductive-system-introduction/the-gonads-and-tubular-genital-tract-in-animals?redirectid=30659

35
Q

Which of the following defects results from abnormal development of the dorsolateral septum transversum or failure of the lateral pleuroperitoneal folds and the ventromedial pars sternalis to unite?

A

Peritoneopericardial diaphragmatic hernia.

Peritoneopericardial diaphragmatic hernia (PPDH) is a congenital malformation of the diaphragm and the most common congenital pericardial disease in dogs and cats.

Essentially, PPDH is a failure of the abdominal and pericardial cavities to separate, allowing herniation of abdominal viscera into the pericardial sac. The liver herniates most commonly, followed by small intestine, spleen, and stomach.

Clinical signs vary and up to 50% of cases are asymptomatic. Thoracic radiographs may show small intestinal loops or liver crossing the diaphragm into the pericardial sac.

Consider surgical correction if evidence of cardiac tamponade, small intestinal obstruction, or hepatic/splenic compromise.

Link: Congenital and Inherited Disorders of the Cardiovascular System in Dogs
https://www.merckvetmanual.com/dog-owners/heart-and-blood-vessel-disorders-of-dogs/congenital-and-inherited-disorders-of-the-cardiovascular-system-in-dogs

36
Q

An adult dog is presented for suspected visual deficits. The owner says the dog keeps bumping into things around the house.
Examination reveals the following:
Pupillary light reflex (PLR) negative direct in L, negative consensual R
PLR positive direct in R, positive consensual L
Menace negative L; positive R
Palpebral positive Land R
Dazzle positive R, negative L
Where is the problem?

A

Left Optic Nerve.

A lesion in the left optic nerve (cranial nerve II / CN Il) would result in these findings: PLR negative direct in L, negative consensual R; PLR positive direct in R, positive consensual
L; menace negative L; menace positive R.
PLRs require integrity of the retina (neural cells), optic nerves, optic chiasm, optic tracts, midbrain (Edinger-Westphal nucleus); and parasympathetic fibers via the oculomotor nerve, ciliary ganglia, and the iridal sphincter musculature. The cerebral cortex is not a part of the PLR.
The menace response involves the retina, CN II, the cerebrum, the cerebellum, and CN VII.
The dazzle reflex involves the retina, CN Il, the rostral colliculus, and CN VII.

Link: Physical and Neurologic Examinations
https://www.merckvetmanual.com/nervous-system/nervous-system-introduction/physical-and-neurologic-examinations#v3286782

37
Q

What condition commonly occurs in the demarcated area that can be treated with trephination and la age?

A

Maxillary Sinusitis.

These markings denote the maxillary sinus, which is common affected by sinusitis.
Horses have six pairs of paranasal sinuses.
In horses, sinusitis is most often due to tooth root infections, since the roots of the four caudal-most cheek teeth extend into the maxillary sinus cavity. However, it can be primary or secondary to a sinus mass (cyst, ethmoid hematoma, neoplasia). Ethmoid hematomas are less commonly found in the paranasal sinuses than in the nasal passages but can be located in the conchofrontal sinus.
Clinical signs of sinusitis include unilateral mucopurulent or bloody nasal discharge (often malodorous if associated with a tooth root infection) and facial deformity.
Dx: Skull radiographs, sinoscopy, additional imaging modalities (e.g., CT or MRI).
Tx: Trephination and lavage of the sinus cavity with systemic antimicrobial therapy.
If sinusitis is secondary to a confirmed tooth root infection or mass (e.g., cyst or
hematoma) within the sinus, must create a sinus flap to repulse the tooth or remove the abnormal material before proceeding with Tx as described above.
Nasofrontal suture periostitis (or exostosis) is characterized by bony, nonpainful swelling over the nasofrontal suture, thought to be secondary to trauma. Tx: topical and systemic antiinflammatories, time.

Check out this good overview of sinus disease (with images) from the American College of Veterinary Surgeons.
https://www.acvs.org/large-animal/sinusitis-in-horses

Image courtesy of Vassil.

Link: Diseases of the Paranasal Sinuses in Horses
https://www.merckvetmanual.com/respiratory-system/respiratory-diseases-of-horses/diseases-of-the-paranasal-sinuses-in-horses

Link: A review of swellings of the frontal region of the equine head
https://beva.onlinelibrary.wiley.com/doi/abs/10.1111/eve.12187

38
Q

One description of a typical heart sounds is “lub-dub”. Wha makes the first heart sound (S1) (i.e., the “lub”)?

A

Closure of atrioventricular valves, opening of semilunar valves.

The first heart sound (S1 or the “lub” in “lub-dub”) is caused by closure of the atrioventricular valves (AV valves, mitral and tricuspid) and opening of the pulmonic and aortic valves (semilunar valves). This is the end of diastole and start of systole.

https://www.merckvetmanual.com/circulatory-system/diagnosis-of-heart-disease/diagnosis-of-heart-disease-in-animals?redirectid=4750?ruleredirectid=30#v3259374

The second sound (S2) is the closure of the aortic and pulmonic valves and opening of the AV valves. This is the end of systole and start of diastole.
A third sound (S3) is the end of rapid ventricular filling and a fourth sound (S4) is atrial systole (atrial contraction).
You can often hear all 4 sounds in horses, but typically hear only S1 and S2 in cattle and small animals.

39
Q

A 19-year-old Saddlebred gelding is presented for acute lameness in the right hind limb. He was trimmed by the farrier 2 weeks ago; he is shod on the fore hooves and goes barefoot behind.
The gelding is 4+/5 lame on the American Association of Equine Practitioners Lameness scale (i.e., extremely lame at the walk).
No heat, swelling, or abnormalities are identified in the right hindlimb and the horse does not resent its manipulation and flexion.
The digital pulse is increased and the horse is extremely sensitive to hoof testers over the medial toe.
What recommendation should be made based on the top differential?

A

Use hoof knife to trim sole at site of sensitivity; place poultice on foot.

It would be most appropriate to use a hoof knife to trim the sole of the hoof at the site of sensitivity and place poultice on foot. This history and clinical exam are consistent with a subsolar abscess (foot abscess).

https://www.merckvetmanual.com/musculoskeletal-system/lameness-in-horses/puncture-wounds-of-the-foot-in-horses

Subsolar abscess is THE most common cause of acute severe lameness in horses. Can be due to a solar bruise, dry to wet hoof conditions, a close nail, or foreign debris.

If the abscess is not opened on the first exam, a poultice is placed to help draw it out.

Sometimes an abscess travels up the hoof and exits at the coronary band instead of at
the solar margin.

Dx - history, exam, hoof tester sensitivity, and paring the white line carefully over the area of hoof tester sensitivity to try to find and open up an abscess pocket. Click here to see a photo of a draining foot abscess.

https://zukureview.com/sites/default/files/2022-07/absole.JPG

Click here to read a good summary article on foot abscesses in horses, courtesy of University of Minn Horse Extension.

https://extension.umn.edu/horse-health/hoof-abscesses

40
Q

This Cow has the shape of a pear on the right and an apple on the left (“pápale”). What is the anatomical abnormality?

A

Ruminal distension.

This is the so-called “papple shape of a cow with ruminal distention due to vagal indigestion (essentially an outflow failure at the reticulo-omasal orifice or pyloric sphincter of the abomasum).
Look for ruminal distention with ingesta (which causes the papple shape) and scant stool.
Rectally, you may note the characteristic “L-shaped” rumen, with the ventral sac of the rumen enlarged and palpable to the right of the midline.
The left kidney may be pushed to the right of the midline by ruminal distention.
Bradycardia is present in 25-40% of cows with vagal indigestion and is NOT commonly associated with other conditions in cattle.
Image courtesy of Dr. Lisle George, copyright 2012.

Link: Chronic Indigestion Syndrome inRuminants

https://www.merckvetmanual.com/digestive-system/diseases-of-the-ruminant-forestomach/chronic-indigestion-syndrome-in-ruminants?autoredirectid=18723

41
Q

What process is associated with testicular descent into the scrotum?

A

Regression of the gubernaculum.

Normal testicular descent is associated with regression of the gubernaculum, a jelly-like cord of tissue which extends through the inguinal canal to co nect the testis and scrotum. As the gubernaculum regresses during fetal development the testes are pulled through the inguinal ring into the scrotum and the remnant gubernaculum becomes the scrotal ligament.

Cryptorchidism is diagnosed if both testes are not in the scrotum at puberty. The timing of normal testicular descent into the scrotum varies among species. For example, in cats testes are present in the scrotum at birth, but in dogs descent maybe delayed up to ten months.

Remember, the developing testes are within the peritoneal (abdominal) cavity and can still communicate with the abdominal cavity after descent through the inguinal ring. This may result in an inguinal hernia, especially common in pigs and horses.

42
Q

What drugs are indicated to treat a cat that is sick with Toxoplasma gondii?

A

Clindamycin or Sulfodiazine.

Treatment for toxoplasmosis is typically clindamycin or a sulfadiazine, pyrimethamine combination. Think of Toxoplasma gondii (with neurologic and ocular manifestations) in association with feline immunodeficiency virus (FIV).

AVOID griseofulvin in FIV-infected cats (or use with extreme caution). May induce severe neutropenia. AVOID use of MLV vaccines also- they may induce disease in immunosuppressed cats.

43
Q

A herd from a swine operation is presented because of an outbreak of fever and lameness in finishing pigs (100 - 200 lb [45-90 kg]). Some animals also have skin lesions that look like the image below. What is the treatment of choice for affected animals?

A

Penicillin IM - acute cases: Cull chronic cases.

Fever, lameness/arthritis and patchy skin lesions in finishing pigs suggest erysipelas. Penicillin is the treatment of choice for ACUTE cases of erysipelas; CULL Chronic cases.

Lincomycin is more frequently used to treat respiratory disease and the polyarthritis associated with Mycoplasma hyosynoviae.

44
Q

Which one of the following plants can cause the problem seen in the following image?

A

Soybeans.

Goitrogenic plants include soybeans, cabbage, rape, kale, and turnips. Foals can be born with hyperplastic goiter and hypothyroidism to dams who eat the plants (especially soybeans), or who are being fed either excessive or inadequate ic Senecio spp, Crotalaria spp., and Amsinckia spp. all contain pyrrolizidine alkaloids (liver damage).

45
Q

Which mycotoxin is associated with moldy red clover due to the fungus Rhizoctonia leguminocola (black patch disease)?

A. Slaframine
B. Ergot alkaloids
C. Aflatoxins
D. Macrocyclic trichothecenes
E. Fumonisin

A

Slaframine toxicosis is due to the fungus Rhizoctonia leguminocola (black patch disease) on red clover (Trifolium pratense) especially in wet, cool years. See profuse salivation, oral irritation, retching and sometimes vomiting, primarily in horses and occasionally in cattle.

Aflatoxicosis is caused by toxigenic strains of Aspergillus (A. flavus, A. parasiticus) on peanuts, soybeans, corn (maize) and other cereal grains. The liver is the major target organ, with widespread hemorrhages, icterus and death in acute cases. Subacute outbreaks are more common, with nonspecific signs of anorexia, weakness, unthriftiness and sudden death.

46
Q

Which one of the following canine urine sediment findings is most commonly seen within six hours after ethylene glycol ingestion?

A. Calcium oxalate monohydrate (6-sided prisms/spindles)
B. Ammonium bitrate crystals (yellow - brown thorn apples)
C. Billirubin crystals (yellow - amber antlers)
D. Calcium carbonate crystals (dumbbells or balls with spokes)
E. Urate crystals (Amorphous)

A

The preferred answer is calcium oxalate monohydrate (6-sided prisms/spindles “picket fences”), which can appear as early as 3 hours post-ingestion in cats and 6 hours post- in dogs.

Click here to see an image of “picket fence” calcium oxalate monohydrate crystals (image on right) on Cornell’s eClinPath website.

Bilirubin crystals can actually be seen in normal dogs (though they are NOT normal in other animals).
P

47
Q

A dorso-ventral (DV) chest radiograph is needed to evaluate an older dog with possible congestive heart failure. Where should the x-ray beam enter the body first?

Thoracic vertebrae
Costo-condral junction
Clavicle
Sternum
Umbilicus

A

Thoracic vertebrae.

For a dorso-ventral (DV) radiograph, the beam enters the dorsal aspect of the chest (the thoracic vertebrae) and exits through the ventral aspect (the sternum).

When correctly positioned, the animal is in sternal recumbency and the sternum is superimposed over the thoracic vertebrae on the film.

48
Q

What is the main reason for clipping hair before an ultrasound procedure?

To increase beam absorption
To decrease scattering
To decrease sound reflection
To avoid damage to the transducer
To increase wave refraction

A

To decrease sound reflection

Hair traps air, which is a major cause of ultrasound reflection.

Ultrasound waves reflected by hair do not enter the animal and result in poor image quality.

Clipping hair from the area of an ultrasound examination and cleaning dirt from the skin will greatly increase the quality of ultrasound image.

The use of transducer gel also helps to ensure good contact between the transducer head and the area being imaged.

49
Q

What thoracic radiographic pattern is most prominent?

Bronchial
Alveolar
Mixed alveolar-vascular
Hilar
Vacular

A

Alveolar.

The air bronchograms are hallmarks of the alveolar pattern. When tiny alveolar airspaces are infiltrated with inflammatory fluid, hemorrhage or neoplasia, the soft- tissue opacity highlights the larger airways.

The other 3 basic lung patterns are:
1. Bronchial pattern, characterized by irregularly thickened walls of bronchioles that look like “donuts” end-on or “tram tracks” side-on. For an excellent visual bronchial pattern summary, see Dr. Allison Zwingenberger’s Vet Radiology site.
2. Interstitial pattern, characterized by decreased visualization of pulmonary vessels, cardiac and diaphragm silhouettes. This particular radiograph is also an example of an interstitial pattern in the caudal lung fields.
3. Vascular pattern can suggest either hypervascularity or hypovascularity.

Click here to see enlarged and tortuous pulmonary arteries in lung the fields of a dog with severe heartworm.

https://www.merckvetmanual.com/multimedia/v49774429

50
Q

Radioactive iodine (I-131) is used to treat which condition?

Diabetes mellitus
Hyperadrenocorticism
Hyperthyroidism
Fanconi’s
Immune-mediated hemolytic anemia

A

Hyperthyroidism

Radioactive iodine (I-131) is used to treat hyperthyroidism and thyroid tumors in therapeutic nuclear medicine.

This article from the Veterinary Medical Teaching Hospital at the University of Pennsylvania gives an overview of I-131 treatment in hyperthyroidism in cats.

51
Q

A herd from a swine operation is presented because of an outbreak of fever and lameness in finishing pigs (100 - 200 lb [45-90 kg]). Some animals also have skin lesions that look like the image below. What is the treatment of choice for affected animals?

Lincomycin in feed - whole herd.
Penicillin IM - acute and chronic cases.
No ecumenically viable treatment - Cull acute cases.
Lincomycin IM - acute cases: Cull chronic cases.
Penicillin IM - acute cases: Cull chronic cases.

A

Penicillin IM - acute cases: Cull chronic cases.

Fever, lameness/arthritis and patchy skin lesions in finishing pigs suggest erysipelas. Penicillin is the treatment of choice for ACUTE cases of erysipelas; CULL Chronic cases.

Lincomycin is more frequently used to treat respiratory disease and the polyarthritis associated with Mycoplasma hyosynoviae.

52
Q

A 2-year-old mixed breed dog is presented with an acutely enlarged eye OS. Intraocular pressure (IOP) is > 30mmHg. You suspect glaucoma. What are some underlying pathologic causes of primary glaucoma?
Ectropion, Interstitial keratitis.
Cataracts, persistent pupillary membranes.
Dacryocystitis, Chorioretinitis.
Closes filtration angle, Goniodysgenesis.
Primary lens luxation, hypema.

A

Closes filtration angle, Goniodysgenesis.

Glaucoma occurs when the normal outflow of aqueous humor is impaired. Primary glaucoma occurs from primary eye disease, like closed filtration angle or goniodysgenesis. Can also see secondary glaucoma from other ocular diseases like lens
luxation, hyphema, anterior uveitis or intraocular tumors.

Primary glaucoma is generally a BILATERAL disease, but often is clinically apparent only in one eye at first. Initial signs are so subtle that it is difficult to identify without measurements of intraocular pressure (IOP).

Most dogs will develop glaucoma in the other eye without prophylactic treatment. Prophylactic Tx with a beta-adrenergic blocker or prostaglandin can delay the onset of glaucoma for up to 2.5 years. “Acute” glaucoma often results from a chronic problem that has finally become so severe that IOP is very high and is an emergency. If the IOP remains elevated for 24-48 hours, irreversible blindness may ensue. Dogs will present with obvious ocular pain, and the eye looks abnormal. Even if the dog is already blind in the affected eye, they should be treated to address the pain.

53
Q

A guinea pig is presented with inappetence, oculonasal discharge, and dyspnea. The clients also have a pet rat, and a pair of rabbits, and these animals all have frequent contact with each other.
Which of the following agents is the most likely cuase?
Clostridium difficile.
Staphylococcus aureus.
Hymenolepis diminuta.
Bordetella bronchiseptica.
Dromaius novahollandiae.

A

Bordetella bronchiseptica.

Rabbits can be subclinical carriers of Bordetella bronchiseptica, which is highly pathogenic in guinea pigs. Because of this cross-species pathogenicity, rabbits and guinea pigs should not be kept together as pets.

Hymenolepis diminuta is a dwarf tapeworm in gerbils. It is possibly zoonotic to humans.

54
Q

A client is upset because half of his frogs have suddenly died after he recently changed out the habitat’s water.
What is the most appropriate next step?
Evaluate for fungal toxins.
Water quality analysis.
Humane euthanasia of remaining frogs, start with fresh stock.
Add tetracycline to tank once a week.
Full physical examinations on all surviving frogs.

A

Water quality analysis.

Water quality analysis will provide information on pH and levels of ammonia metabolites, chlorine, oxygen, etc. These are all critical factors in tank health. Buildup of ammonium and nitrate levels in the habitat of aquatic amphibians can lead to significant disease and death.

New tank syndrome is a buildup of ammonia metabolites due to lack of bacteria in new tanks (or right after all the water has been switched out). It can take up to 6 weeks for a new tank to become efficient in nitrogen metabolism.

In well-established aquariums, bacterial flora metabolizes ammonium to nitrite and nitrate. Nitrogen metabolite levels (e.g., ammonium, nitrate, and nitrite) must be weekly monitored in the habitat using a water-test kit.

55
Q

A seven-year-old neutered male Rottweiler-mix dog from the Southern US in poor body condition presents with a one-month history of exercise intolerance, non-productive cough and heavy breathing.
The dog lives outside the house, last received routine vaccinations four years ago, and does not receive any other medications. Physical exam reveals mild cyanosis, ascites, temperature of 102.1oF, (38.9oC).
What is the most appropriate test to do to support the presumptive diagnosis?

Contrast angiography for patent ductus arteriosus.
Electrocardiogram for left heart failure.
Heartworm antigen test.
Complete blood count and blood chemistry panel.
Echocardiogram for dilated cardiomyopathy.

A

Heartworm antigen test.

The preferred answer is to test for heartworm disease. The history of outdoor living, in the South where Dirofilaria immitis-infected mosquitoes bite year-round, and the LACK of a history of preventative medication puts heartworm at the top of the DDX.

Patent ductus atreriosus (PDA) is more typically a young dog congenital abnormality that presents with exercise intolerance, coughing, stunted growth and a continuous machinery-type murmur, loudest on auscultation over the left craniodorsal cardiac base.