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Rabbits > BB LRGPHOR Ch14 - Rabbit Viral Diseases > Flashcards

BB LRGPHOR Ch14 - Rabbit Viral Diseases Flashcards

1
Q
  1. Myxoma virus in rabbits results in a severe, systemic disease in which species: a. Lepus tinidus b. Sylvilagus braziliensis c. Oryctolagus cuniculus d. Sylvilagus floridanus
A

c

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2
Q
  1. Which of the following contains only intracytoplasmic inclusions? a. Myxoma virus b. Rabbit Hemorrhagic Disease Virus c. Rabbit Oral Papillomavirus d. Herpesvirus cuniculi e. Rabbit Kidney Vacuolating Virus
A

a. Myxoma virus

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3
Q
  1. Which virus closely resembles Shope fibromatosis in Sylvilagus species, but causes a rapid, fatal infection in Oryctalagus species?
A

Myxoma virus

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4
Q
  1. What is a diagnostic distinction between Shope fibromatosis and papillomatosis in rabbits?
A

Presence of intranuclear inclusions

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5
Q
  1. Which of the following viruses of rabbits in the family Poxviridae is an Orthopoxvirus? a. Hare Fibroma Virus b. Rabbit (Shope) Fibroma Virus c. Myxoma Virus d. Rabbit Poxvirus
A

d. Rabbit Poxvirus

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6
Q
  1. Indicate whether the following viruses are DNA or RNA viruses: a. Rabbit Hemorrhagic Disease Virus b. Rabbit Fibroma Virus c. Leporid Herpesvirus 1 d. Rotavirus e. Lapine parvovirus f. Shope Papillomavirus
A

a. Rabbit Hemorrhagic Disease Virus - RNA b. Rabbit Fibroma Virus - DNA c. Leporid Herpesvirus 1 - DNA d. Rotavirus - RNA e. Lapine parvovirus - DNA f. Shope Papillomavirus - DNA

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7
Q
  1. Which of the following viruses is anthropozoonotic in humans and rabbits? a. Poxvirus b. Herpesvirus c. Papillomavirus d. Calicivirus
A

b

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8
Q
  1. To what genus does Cottontail Rabbit Papillomavirus belong? a. Papillomavirus b. Polyomavirus c. Kappapapillomavirus d. Betapapillomavirus
A

c

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9
Q
  1. True or False: Rabbit Oral Papillomavirus is immunologically identical to Cottontail Rabbit Papilomovirus.
A

FALSE

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10
Q
  1. Which of the following in nonpathogenic for all rabbit species? a. Rabbit Kidney Vacuolating Virus b. European Brown Hare Syndrome Virus c. Leporid parvovirus 4 d. Rabbit Hemorrhagic Disease Virus
A

a

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11
Q
  1. Which of the following is not typically a cause of diarrhea in young rabbits? a. Rabbit Hemorrhagic Disease Virus b. Rotavirus c. Coronaviral enteritis d. Colibacillosis
A

a

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12
Q
  1. Which of the following is most effective at eliminating rotavirus? a. Chlorine b. Formalin c. 95% Ethanol d. Betapropriolactone
A

c

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13
Q
  1. Which of the following is not a pathologic lesion associated with rotavirus? a. Intestines markedly congested and distended b. Villous blunting c. Mucosal hemorrhages d. Proliferative ileitis
A

d

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14
Q
  1. True or False: It is possible to rederive rabbits free of rotaviral infection through early weaning.
A

True

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15
Q
  1. Which of the following types of viruses may be a useful model for virus-induced cardiomyopathy? a. Coronavirus b. Calicivirus c. Parvovirus d. Bunyavirus
A

a

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16
Q
  1. The “etiologic agents of necrotic hepatitis of leporids” are classified as what type of viruses? a. Calicivirus b. Coronavirus c. Flavivirus d. Herpesvirus
A

a

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17
Q
  1. What is the most consistent finding in Rabbit Hemorrhagic Disease Virus?
A

Pale liver with periportal necrosis

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18
Q
  1. Which of the following viruses does not result in clinical disease in rabbits? a. European Brown Hare Syndrome Virus b. Rabbit Calicivirus c. Michigan Rabbit Calicivirus d. Rabbit Hemorrhagic Disease Virus
A

Rabbit Calicivirus

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19
Q
  1. Which of the following rat viruses do rabbits develop antibodies to? a. Sendai virus b. Rat Respiratory virus c. Sialodacryoadenitis Virus d. PVM
A

a

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20
Q
  1. Which of the following species is not involved in perpetuation of the flavivirus, Powassan virus? a. Peromyscus leucopus b. Lepus americanus c. Marmota monax d. Octodon degus
A

d

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21
Q

Causative agent of myxomatosis

A

Myxoma virus

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22
Q

Characteristics of myxoma virus

A

Family Poxviridae, genus Leporipoxvirus Enveloped double stranded DNA virus

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23
Q

Clinical signs of myxomatosis

A

Oryctolagus - mucinous skin lesions and tumors, edema around mouth, nose, anus, genitals progressive conjunctivitis

24
Q

Epizootiology of myxoma virus

A

Oryctolagus particularly susceptible flea and mosquito vectors, direct contact Sylvilagus and Lepus spp. naturally susceptible

25
Q

Pathogenesis of myxomatosis

A

immunomodulatory proteins inhibit apoptosis, leukocyte chemotaxis, leukocyte activation

26
Q

Pathology of myxomatosis

A

myxomas - undifferentiated stellate mesenchymal cells embedded in mucinous matrix with capillaries and inflammatory cells

27
Q

Diagnosis of myxomatosis

A

PCR, ELISA, culture virus from tissue

28
Q

Differential diagnosis of myxomatosis

A

In Sylvilagus, lesions indistinguishable from rabbit fibroma virus - fibroma. Inoculate Oryctolagus with material to determine if it is myxoma virus (fatal) or fibroma virus (fibroma)

29
Q

Characteristics of Shope fibroma virus

A

Family Poxviridae, genus Leporipoxvirus similar to myxoma virus Enveloped, double stranded DNA virus

30
Q

Epizootiology of Shope fibroma virus

A

endemic in wild rabbits - causes fibromas skin tumors in domestic rabbits arthropod vectors spontaneously regress

31
Q

Clinical signs of Shope fibroma virus

A

flat, subcutaneous, easily movable tumors on legs and face

32
Q

Characteristics of rabbit pox virus

A

Family Poxviridae, genus Orthopoxvirus

33
Q

Clinical signs of rabbit pox virus

A

fever nasal discharge eye lesions - blepharitis, conjunctivitis, keratitis widespread skin lesions - macules/papules rash enlarged lymph nodes, facial edema

34
Q

Pathology of rabbit pox virus

A

nodules on liver, gall bladder, spleen, lung, repro organs widespread necrosis Cytoplasmic inclusions are reare

35
Q

Characteristics of Shope papilloma virus

A

Family Papovaviridae, genus Kappapapilomavirus nonenveloped double stranded DNA virus

36
Q

Clinical signs of Shope papilloma virus

A

horny warts an the neck, shoulders abdomen

37
Q

Epizootiology of Shope papilloma virus

A

widespread geographic distribution SCC in Sylvilagus spp. arthropod vector

38
Q

Characteristics of rabbit rotavirus

A

Family Reoviridae, group A, serotype 3 Nonenveloped double stranded RNA virus

39
Q

Clinical signs of rabbit rotavirus

A

anorexia, dehydration, watery to mucoid diarrhea, death

40
Q

Epizootiology of rabbit rotavirus

A

weanlings most susceptible newborns resistant due to passive immunity

41
Q

Pathology of rabbit rotavirus

A

villous atrophy, loss of small intestinal epithelial cells’ lymphocytic infiltrate

42
Q

Diagnosis of rabbit rotavirus

A

immunoassays

43
Q

Characteristics of rabbit coronavirus

A

Family Coronaviridae Enveloped single stranded RNA virus

44
Q

Causative agent of rabbit hemorrhagic disease

A

Rabbit hemorrhagic disease virus family Caliciviridae nonenveloped single stranded RNA

45
Q

Clinical syndromes of rabbit hemorrhagic disease

A
  1. acute - anorexia, depression, neuro and resp. signs, ocular hemorrhage, epistaxis 2.peracute - sudden death 3. subacute - mild clinical signs
46
Q

Epizootiology

A

first described in China 1984 now widespread in Europe, Asia, Africa, Australia, NZ fecal oral transmission suspected fomite and arthropod vectors

47
Q

Pathology of rabbit hemorrhagic disease virus

A

periportal hepatic necrosis DIC, thrombosis

48
Q

Diagnosis of rabbit hemorrhagic disease

A

electron microscopy of liver tissue ELiSA

49
Q

Differential diagnosis of rabbit hemorrhagic disease

A

European brown hare virus (calicivirus)

50
Q

This clinical condition is caused by what kind of virus?

a. polyomavirus
b. calicivirus
c. rotavirus
d. papillomavirus

A

b. calicivirus

Rabbit hemorrhagic fever

genus: Lagovirus

51
Q

Taxonomy of causative agent of this histopathology

A

Family Poxviridae

Genus Leporipoxvirus

52
Q

which genus of rabbit is most susceptible to this diseasse?

a. Lepis
b. Sylvilagus
c. Oryctolagus
d. Bunolagus

A

c. Oryctolagus

53
Q

What is the genus of agent that causes this clinical presentation:

a. Leporipoxvirus
b. Orthopoxvirus
c. Kappapapillomavirus-1
d. Kappapapillomavirus-2

A

c. Kappapapillomavirus-1

54
Q

What is the mode of transmission of the agent that causes this histopathologic presentation?

a. horizontal (placental)
b. fecal-oral
c. exposure to spores in the environment
d. arthropod vector

A

b. fecal-oral

Rabbit hemorrhagic fever virus

55
Q

Arrows pointing to intranuclear inclusion bodies associated with what agent?

a. Leporipoxvirus
b. Kappapapillomavirus-1
c. Orthopoxvirus
d. Kappapapillomavirus-2

A

a. Leporipoxvirus (Shope Fibroma virus)

56
Q

Causative agent of this condition:

a. Leporipoxvirus
b. Orthopoxvirus
c. ppapapillomavirus
d. Psoroptes

A

a. Leporipoxvirus

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