Basics Flashcards
Pharacology
study of drugs and their interactions on living systems (draws on knowledge from anatomy and physiology, pathology, chemistry, and psychology)
Pharmacist
a person who dispenses drugs at a pharamcy
Pharamacologist
is a scientists who studies all aspects of drugs, including their origins, functions chemistry, effects and uses
Medicinal chemisitry
study of new-drug synthesis
Pharmacodynamics
study of drug action and effects on the body
Molecular pharmacology
study of the interaction of drugs, with molecules such as DNA, RNA, and enzymes
Pharmacotherapeutics
treatment of disease with therapeutic medications
Toxicoloy
study of poisons
Drugs
substances that change physiological processes in the body
Plant
have always provided effective folk remedies
Minerals
naturally occurring substances usually come from the ground
Animals
another natural source of drugs; substances missing from human body may be found in body tissues of animals
Synthetic Drug
since 19th century science has made it possible to manufacture drugs from chemicals in laboratory
Recombinant DNA Technology
uses artificially manipulated DNA segments from different organic sources by transferring a cell from a different species to a host cell to change the way the cell reproduces
Pharmacokinetics
refers to the movement of drug through the body
Absorption
refer to the movement of a drug from site of administration into the blood
Distribution
the movement of a drug from the blood into the isses and cells
Metabolism
involves physical and chemical alteration of the drug in the body
Excretion (elimination)
refers to the removal of waste products of drugs metabolism from the body
Primary site absorption
1. mucosa of the mouth 2, lungs 3, stomach 4. small intestine and rectum 5. subcutaneous tissue 6. blood vessels in muscle tissue
Factors that can influence absoprtioin
- administration
- drug pH
- food
- location
- topical
- inhalation
Drug Blood Level
amount of drug circulation in the bloodstream
Fat Solube
stored in the fatty tissues and provide a relatively stable reserve of the drug
Metabolism
process of chemical reactions that change the drugs water-soluble compounds for excretion
Half-liver
the body times it take to metabolize half the available drug
Pharmacodynasmic
refer to the way in which a drug works, such as its mechanism of action in the body or the body’s chemical reaction to the drug
Desired Effect
expected response occurs from the drug adminstration
Side Effect
occur when a predictable but undesired response occur
Local Action
limited to the site of administration and the area immediately surrounding the application site
Symstemic action
drug effect occurs throughout the body
Pharacotherapeutics
the effect of a drug in the treatment of disease
Toxicology
study of the adverse effects that chemicals (and drugs) can have on living systems)
Antidote
used to counteract the effect of an excessive drug toxicity level
Adverse effects
uninteneded and undesirable effects that results from a drug (allergic reaction)