Basic Lung Function Flashcards

1
Q

Why is testing lung function useful?

A
  • Evaluate lung function patterns in conjunction with patient’s history + exam aids diagnosis
  • Can follow changes under normal circumstances + in response to treatment
  • Assess changes in response to specific stimuli in lab or environment e.g. occupational asthma
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2
Q

What 3 different things can you measure in terms of lung function?

A
  1. Air flow rate: diameter of airways indication
  2. Vital capacity: measure of total lung volume
  3. How quickly gas diffuses into blood: measure of permeability of lung membranes + V/Q matching
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3
Q

What is vital capacity?

A

Measured from max inspiration to max inhalation so patient must take biggest breath in = good indicator of total lung volume

Air left in lungs is residual volume

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4
Q

What is a expiratory peak flow diary?

A

Uses a peak flow meter + diary to record values + symptoms

Max achievable expiratory flow determined by diameter of bronchial tree + muscle power available in L/minute

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5
Q

What are the advantages + disadvantages of the expiratory peak flow diary?

A

Adv: easy + cheap equipment

Diadv: technically easy to mess up so patient must know how to do it

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6
Q

What is the correct way of using a peak flow meter?

A
  • Check pointer is at 0
  • Stand/sit comfortably (keep same position if repeated)
  • Hold it horizontally keeping fingers away from pointer
  • Take deep breath out, deep breath in + wrap lips tightly round mouthpiece
  • Blow as hard as you can using max force
  • Check reading on pointer
  • Rest back to 0
  • Do 3 x + record highest value obtained
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7
Q

How will you know using a peak flow chart if someone has asthma? What should happen when treatment with a preventer inhaler starts?

A

> 20% variability between morning + evening readings (mornings usually lower) because airways are opening + closing (wheeze when closed)

Readings improve although slight variability still (which is normal) - response to treatment can aid diagnosis

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8
Q

What is used as a asthma preventer inhaler + relief inhaler?

A

Preventer: steroids
Reliever: B-agonist

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9
Q

What is spirometry?

A

Measures forced expiratory volume in one second (FEV1) + forced vital capacity (FVC)

Patient must do the FVC manouvere + the machine will print out a reading + drawing

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10
Q

What are the advantages + disadvantages of spirometry?

A

Adv: most readily available + useful lung test, takes 10-15 mins, little risk, internationally accepted criteria exist ensure results are optimal/repeatable + normal values been defined for + differ between populations

Disadv: expensive, requires lung function technician experts with significant training

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11
Q

Is the exhalation performed in expiratory peak flow + spirometry the same?

A

No

Expiratory peak flow is a big, very sudden + forceful breath out

But, spirometry exhalation should be a big breath out slowly + continued for as long as possible

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12
Q

What is the advantage of taking FEV1 in spirometry rather than peak expiratory flow?

A

Gives muscle independent flow so essentially gives an indicator of diameter of airways

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13
Q

What will a flow volume loop look like from a spirometry test in a healthy patient?

A

Flow will rapidly increase at first + then decrease because the lung is getting smaller + diameter of air pipes is getting smaller becoming the limiting factor despite muscle power (should get around ~ 550)

Declining line will hit volume axis at tight angle whereas emphysema lungs for e.g. will plateau to 0 as they cannot get air out of lungs as quickly

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14
Q

What will be lower in diseased lungs on a time volume loop than shown for a healthy lung?

A

FVC i.e. max volume that patient gets too - plateau will be a lot lower than in a healthy lung

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15
Q

What does restrictive lung disease (e.g. fibrotic/scarred lungs) look like in spirometry readings?

A

Small lungs show a restrictive spirometry pattern - reduced FVC (tall narrow curve)

Compatible spirometry supportive of clinical working diagnosis if used alongside supportive history + cracking noise on chest examination (alveoli collapsing early + popping open again)

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16
Q

What is the commonest cause of restrictive spirometry?

A

Failure to breathe out fully during the test so need technician to tell patient to carry on pushing out till they cannot anymore

17
Q

What happens to the spirometry reading in airways obstruction disease e.g. emphysema?

A

Airways are narrowed so time taken to empty lungs in exhalation is increased -> FEV1 reduced (concave up curve)

Increased residual volume (more air trapped behind in obstructed bronchi) - not measured by spirometry

In conjunction with narrowing causing turbulent flow which can be heard as wheeze + barrel shaped/hyperinflated chest on examination

18
Q

What is total lung capacity?

A

Vital capacity + residual volume

19
Q

What will a spirometry curve shown if the patient has a fixed obstruction i.e. tumour around their trachea?

A

Fixed obstruction which will not change with breathing as trachea will not be able to open or close so you will see straight horizontal lines for inspiratory + expiratory flow i.e. fixed maximums either way

20
Q

How can FEV1 and FVC be used together?

A

Normal FEV1 +FVC = > 80% of predicted

If you look at ratio, FEV1 reduced more than FVC = ratio < 0.7 (obstructive)

FVC is reduced more than FEV1 = ratio > 0.7 (restrictive)

21
Q

What are FEV1 and FVC predictions based on?

A
  • Normal distribution of population
  • Height
  • Weight
  • Sex
22
Q

How can we directly measure gas diffusion?

A

Direct measurement of rate at which carbon monoxide diffuses across lung membranes into blood

Compared to normal values for population + expressed as % of normal

= Diffusion Capacity for Carbon Monoxide (DLCO) - reduced in restrictive + obstructive lung disease due to less SA

23
Q

What is direct measurement of gas diffusion used to assess?

A

Permeability of entire respiratory system including:

  • Shunts
  • Less permeable membranes
  • V/Q mismatch
24
Q

What are contraindications to lung function?

A

Risk vs benefit:

  • Haemoptysis
  • Closed or recent (2 weeks) pneumothorax
  • Unstable CV status, pre-eclampsia + hypertension (MAP > 130 mmHg)
  • Thoracic, abdominal or cerebral aneurysms
  • Acute illness
  • Recent thoracic, ear, ocular or abdominal surgery
  • Active communicable diseases
25
Q

Why is there contraindications to lung function tests?

A

As maximal pressure is generated in the thorax so there will be impact on thoracic + abdominal organs

Also, large swings in BP + expansion of chest wall + lungs occurs

26
Q

What other conditions may affect the lung function results?

A

Acute respiratory conditions
Pain
Pregnancy