Basic Eye Disorders 1 Flashcards
Cataracts affects which population?
1 in 2 elderly
Cataract is due to _____ damage to the lens proteins that reduce _____.
- oxidative
- solubility
(insoluble OPACITIES form in otherwise transparent tissue)
In cataract, ________ w/in lens causes clouding of vision and progressive vision loss.
protein clumping (coagulation and crystallization)
Senile cataracts is _______ (unilateral/bilateral) and has a ______ appearance.
- unilateral or bilateral
- radial
Cataracts has 3 main pathophysiologic causes*** (***different than risk factors; see chronic vision loss)
(other than idiopathic)
- congenital/viral
- chromosomopathy (trisomy 21)
- inborn error of metabolism
First dx test done if you suspect cataracts
pin hole
pin hole test
visual acuity chart through a pin hole, if it improves then nothing wrong w/ macula or retina.
How is cataracts dx?
Examining fundus: reduced or obstructed red reflex
Diabetic retinopathy occurs in almost all ______ patients and the majority of _____ patients
- DMT1
- DMT2
Diabetic retinopathy affects 1 in _____.
2,500
______ are particularly affected by increased blood sugar and lose the ability to auto-regulate.
Vascular pericytes
hemorrhage over the macula will lead to _______.
sudden vision loss
What causes cotton-whool spots?
retinal capillaries infarct → hypoxia
(possibly infarct of neuron → mitochondrial accumulation at the swollen ends)
neovascularization (diabetic retinopathy) is the result of _______.
ischemia
What is the main difference in proliferative vs. non-proliferative diabetic retinopathy
neovascularization
(proliferative can hemorrhage→visualized with green slit)
diabetic retinopathy occurs 10-15 years after dx, and chronic retinal problems can lead to ________.
retinal detachment → sudden vision loss
(TQ!!)