basic concepts of biosafety and biosecurity Flashcards

1
Q

Brief history of laboratory biosafety:
In 1967, there is an increase in… and… due to the…

A

Mortality & morbidility
Smallpox

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2
Q

Brief history of laboratory biosafety:
When was the serious concerns about the biosafety practice worldwide were raised

A

1967

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3
Q

Brief history of laboratory biosafety:
Where did the serious concerns about biosafety practices worldwide were consolidated?

A

Russia: State Research for Virology and Biotechnology VECTOR
US: Centers for Disease Control and Prevention (CDC)

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4
Q

Brief history of laboratory biosafety:
Who described the use of mechanical pipettors to prevent laboratory acquired infections

A

Arnold Wedum

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5
Q

Brief history of laboratory biosafety:
When was the use of mechanical pipettors to prevent laboratory acquired infections?

A

1907 & 1908

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6
Q

Brief history of laboratory biosafety:
Who is the director of Industrial Health and Safety in 1944

A

Arnold Wedum

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7
Q

Brief history of laboratory biosafety:
Who provided the foundation for evaluating the risks handling infectious microorganisms

A

One of the pioneers of biosafety

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8
Q

Brief history of laboratory biosafety:
The use of mechanical pipettor is to prevent…

A

Laboratory acquired infections

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9
Q

Brief history of laboratory biosafety:
When did the pharmaceutical company in Pennsylvania developed a ventilated cabinet to prevent infection from myobacterium tuberculosis

A

1909

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10
Q

Brief history of laboratory biosafety:
The pharmaceutical company in Pennsylvania developed a … to prevent …

A

ventilated cabinet
infection from myobacterium tuberculosis

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11
Q

Brief history of laboratory biosafety:
Who developed a ventilated cabinet to prevent infections from mycobacterium tuberculosis

A

A pharmaceutical company in Pennsylvania

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12
Q

Brief history of laboratory biosafety:
When did the US biological weapons program began and who ordered it

A

1943, US President Franklin Roosevelt

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13
Q

Brief history of laboratory biosafety:
When did WHO aggressively pursued the eradication of the virus

A

1967

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14
Q

Brief history of laboratory biosafety:
How did the WHO aggressively pursued the eradication of the virus

A

Through vaccination

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15
Q

Brief history of laboratory biosafety:
Newell A. Johnson developed what technical solutions?

A

Class III Safety Cabinets and laminar flow hoods

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16
Q

Brief history of laboratory biosafety:
Camp Detrick was renamed to

A

Fort Detrick

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17
Q

Brief history of laboratory biosafety:
Who analyze the multiple epidemiological studies for laboratory-based outbreak

A

Wedum and microbiologist Morton Reitman

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18
Q

Brief history of laboratory biosafety:
when did Wedum and Morton Reitman analyzed multiple epidemiological studies of laboratory-based outbreak

A

1966

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19
Q

Brief history of laboratory biosafety:
Who is the microbiologist and a colleagues at Fort Detrick

A

Morton Reitman

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20
Q

Brief history of laboratory biosafety:
Who terminated the US biological weapons program

A

US President Richard Nixon

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21
Q

Brief history of laboratory biosafety:
When was the Biological weapons program terminated

A

1969

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22
Q

Brief history of laboratory biosafety:
When did the CDC published Classification of Etiological Agents on the Basis of Hazard

A

1974

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23
Q

Brief history of laboratory biosafety:
In 1974, what did the CDC published

A

Classification of Etiological Agents on the Basis of Hazard

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24
Q

Brief history of laboratory biosafety:
When was the national Institution of Health published NIH Guidelines for Research Involving Recombinant DNA Molecule

A

1976

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25
Brief history of laboratory biosafety: In 1976, what did the national Institution of Health published
NIH Guidelines for Research Involving Recombinant DNA Molecule
26
Brief history of laboratory biosafety: When was the World Health Organization’s first edition of Laboratory Biosafety Manual
1983
27
Brief history of laboratory biosafety: In 1983, what is the World Health Organization’s first edition
Laboratory Biosafety Manual
28
Brief history of laboratory biosafety: When did NIH and CDC’s joint-published first edition of Biosafety in Microbiological and Biomedical Laboratories
1984
29
Brief history of laboratory biosafety: In 1984, NIH and CDC’s joint-published first edition of
Biosafety in Microbiological and Biomedical Laboratories
30
Technical means of mitigating the risk of accidental infection from or release of agents in the laboratory setting as well as the community and environment it is situated in.
Biosafety levels
31
Brief history of laboratory biosafety: Progress of biosafety continued until the emergence of a community of “___” who adopted the administrative role of ensuring that the ____ and ____ are in place
“biosafety officers” proper equipment facility controls
32
Identify: 1. Classification of Etiological Agents on the Basis of Hazard 2. Laboratory Biosafety Manual 3. Biosafety in Microbiological and Biomedical Laboratories 4. NIH Guidelines for Research Involving Recombinant DNA molecule
1. CDC 2. WHO’s first edition 3. NIH and CDC’s joint-published 4. National Institute of Health
33
Brief history of laboratory biosafety: Who became the first scientific director of camp detrick
Ira L. Baldwin
34
Brief history of laboratory biosafety: Ira L. Baldwin became the first…
First scientific director of camp detrick
35
Brief history of laboratory biosafety: Newell A. Johnson engaged some of Camp Detrick’s leading scientist about the…
nature of their work
36
Brief history of laboratory biosecurity: Which year did the US government enacted Select Agent Regulation
1966
37
Brief history of laboratory biosecurity: In 1966, the US Government enacted…
Select Agent Regulation
38
Brief history of laboratory biosecurity: Who monitor the transfer of a select list of biological agents from one facility to another
Select agent Regulation
39
Brief history of laboratory biosecurity: When was the revised agent regulation the requires specific security measures for any facility in the United Staes that used or stores one or more agents on the longer list of agents
2001
40
Brief history of laboratory biosecurity: In the Select Agent Regulation in 2012, how many of tiers of select agents are there
Two tier of select agents
41
Brief history of laboratory biosecurity: Materials that pose the greater risk of deliberate misuse and the remaining select agents
Tier 1 agents
42
What is Singapore select agent regulation
Biological agent and toxins act
43
What is South Korea select agent regulation
Act on prevention of infectious disease (2005)
44
What is Japan select agent regulation
Infectious disease control law
45
What is Canada select agent regulation
Containment Levels 3 and 4
46
Identify the country: Act on prevention of infectious disease Containment levels 3 and 4 Biological agent and toxins act Infectious disease control law
South Korea (2005) Canada Singapore Japan
47
When was the biological agent and toxins act introduced
October 2005
48
When was the biological agents and toxins enacted
January 2006
49
What is the European committee for standardization
(CEN) Comite Europeen de Normalisasyon
50
What do Comite Europeen de Normalisasyon published
(CWA 15793) CEN Workshop Agreement 15793
51
What do (CWA 15793) focuses on
Laboratory biorisk management
52
It is applied to international stakeholders, however, they do not have the force of regulation while conformity is voluntary
CWA 15793
53
CWA 15793 is applied to …, however, they do not have the force of regulation while conformity is…
international stakeholders voluntary
54
CWA 15793 has experts from how many country
24
55
When did WHO published the 3rd edition of Laboratory Biosafety Manual which includes information on the different levels of containment laboratories
1983
56
When did the European committee for Standardization published CEN Workshop Agreement 15793 (CWA 15793)
Feb 2008
57
In 1983, WHO published the...
3rd edition of laboratory biosafety Manual
58
What is included in the 3rd edition of laboratory biosafety Manual
The different levels of containment laboratories
59
Cartagena protocol on biosafety is made effective in..
2003
60
What is made effective in 2003
Cartagena protocol biosafety (CPB)
61
Cartagena protocol on biosafety applies to the...
168 - member countriess
62
Cartagena protocol on biosafety ensure an adequate level of protection in the field of ____ , ____, and ____
safe transfer handling use of living modified organisms
63
What is the executive order of the National Committe on Biosafety of the Philippines
E.O. 430 Series of 1990
64
National Committe on Biosafety of the Philippines was formed on the … of scientist
advocacy efforts of scientist
65
The office of the president promulgated the executive order..
E.O. 514
66
When was the office of the president promulgated E.O 514
March 17 2006
67
Office of the president promulgated E.O. 514 establishing the
National biosafety framework
68
Combination of policy, legal, administrative, and technical instrument developed to attain the ___
objective of Cartagena Protocol on Safety
69
Combination of policy, legal, administrative, and technical instrument developed to attain the objective of Cartagena Protocol on Safety which the Philippines signed on…
May 24 2000
70
What are the 5 different organizationsin the field of biosafety
1.ABSA -America biological safety association 2. EBSA -European biological safety association 3. A-PBA -Asia-pacific biosafety association 4. PhBBA- Philippine biosafety and biosecurity association 5. BRAP -biological risk association Philippine
71
When was the ABSA founded
1984
72
When was the A-PBA founded
2005
73
When did the EBSA founded
June 1996
74
Identify the organizations in the field of biosafety: Promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory regime present in North America
ABSA
75
Identify the organizations in the field of biosafety: Biosafety professionals in the Asia-Pacific region.
A-PBA
76
Identify the organizations in the field of biosafety: Aims to provide forum for discussions and debates on issues of concern and to represent those working in the field of biosafety
EBSA
77
Identify the organizations in the field of biosafety: Assists the DA and DOH in their efforts to create a national policy and implements plan
PhBBA
78
Identify the organizations in the field of biosafety: Created by members from health and education sectors from executive, legislative, and judicial branches
PhBBA
79
Identify the organizations in the field of biosafety: Non-government and non-profit association that works to serve the emergent concerns of biological risk management in various professional fields
BRAP
80
The members of A-PBA are from
Singapore Brunei Indonesia Malaysia Thailand China
81
EBSA aims to provide … and … and to represent those working in the field of biosafety
Forum of discussion Debates on issue of concern
82
Focuses on … and … among its members … and … on biosafety and biosecurity
Encouraging and communicating Information and issues
83
PhBBA is created by members from health education sectors from…., …., ….
Executive Legislative Judicial branches
84
PhBBA included members of the steering committee and technical working groups of the national laboratory biosafety and biosecurity action plan task force established …
DPO No. 2006-2500
85
PhBBA assist DA and DOH in their efforts to create a … and …
national policy implement plan
86
As defined by WHO: “The containment principles, technologies, and practices that are implemented to prevent unintentional exposure to pathogens and toxins, or their accidental release.”
Biosafety
87
“The protection, control, and accountability for valuable biological materials within laboratories, in order to prevent their unathuroized access, loss, theft, misuse, diversion, or inential release.”
Biosecurity
88
It protects people from germs
Biosafety
89
If protects germs from people
Biosecurity
90
Who is the environmental health engineer
Charles Baldwin
91
Charles Baldwin works for the
Dow chemical company
92
Charles Baldwin is a…
Environmental health engineer who works for the Dow chemical company
93
Biosafety: The containment principles, technologies, and practices that are implemented to prevent
unintentional exposure to pathogens and toxins or their accidental release
94
The …, …, … for valuable biological materials within laboratories, in order to prevent their unathuroized access, loss, theft, misuse, diversion, or inential release
protection, control, and accountability
95
Identify the risk group: Low individual & community risk.
Risk group 1
96
Identify the risk group: Unlikely to be asignificant risk to lab workers, enviro, community, livestock
Risk group 2
97
Identify the risk group: Significant risk to lab workers
Risk group 3 and 4
98
Identify the risk group: Unlikely to cause human or animal disease
Risk group 1
99
Identify the risk group: May cause infection
Risk group 2
100
Identify the risk group: Serious disease to humans/animals
Risk group 3
101
Identify the risk group: Life threatening disease to humans /animals
Risk group 4
102
Identify the risk group: Effective treatment Preventive measures
Risk group 2 and 3
103
Identify the risk group: No treatment and readily transmissible from one individual to another
Risk group 4
104
Identify the biosafety level: Suitable for work involving viable microorganisms gar are defined and with well-characterized strains known not to cause disease in humans
Biosafety level 1
105
Identify the biosafety level: Designed for laboratories that deal with indigenous moderate-risk agents present in the community
Biosafety level 2
106
Identify the biosafety level: Emphasis on primary and secondary barriers in the protection of personnel, community and environemt from infectious aerosol exposure
Biosafety level 3
107
Identify the biosafety level: Work with indigenous and exotic agents with a potential for respiratory transmission and may cause serious and potentially lethal infection
Biosafety level 3
108
Identify the biosafety level: Required for work with dangerous and exotic agents that pose high individual risks of life-threatning disease that may be transmitted via he aerosole route which there are no available treatment or vaccine
Biosafety level 4
109
Identify each laboratory biosafety according to levels: Indigenous and exotic agent Viable microorganisms gar Dangerous and exotic agents Indigenous moderate-risk agents
Biosafety level 3 Biosafety level 1 Biosafety level 4 Biosafety level 2
110
What are some examples of biosafety level 1
Bacillus subtilis, Naegleria gruberi, infectious canine hepatitis virus and exempt organisms
111
What are some examples of biosafety level 2
Hepatitis B virus, HIV, salmonellae, and Toxoplasma species
112
What are some examples of biosafety level 3
Mycobacterium tuberculosis, St. Louis encephalitis virus, and Coxiella
113
What are some examples of biosafety level 4
Margburg or the Crimean-Congo hemorrhagic fever