Basal Ganglia physio Flashcards
1
Q
Role of basal ganglia
A
Control beginning and end of motion
2
Q
How does basal ganglia operate?
A
Via inhibition and withdrawal of inhibition (excess of GABA)
3
Q
General pathways from BG?
A
Pars compact of substantia nigra (SNPC) to striatum
4
Q
Direct pathway (receptors, effect)
A
- D1 receptors
- Excited by dopamine
- Allows motion
5
Q
Indirect pathway (receptors, effect)
A
- D2 receptors
- Inhibited by dopamine
- Excited by EAA/Ach
- Inhibits motion
