basal ganglia Flashcards

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1
Q

where are the basal ganglia

A

subcortical around the thalamus and above amygdala

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2
Q

how do the basal ganglia allow switiching between motor programmes

A

inhibit antagonistic and unnecessary mvt, regulate appropriate force of mvt

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3
Q

what is the dorsal striatum

A

caudate nucleus and putamen

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4
Q

what is caudate nucleus and putamen called

A

dorsal striatum

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5
Q

what is lentiform nucleaus

A

putamen an globus pallidus

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6
Q

what is putamen and globus pallidus

A

lentiform nucleus

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7
Q

what separaates the caudate nucleus and putamen

A

internal capsule

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8
Q

from this rear view, what are red, gold and pink

A

red: caudate nucleus
gold: putamen
pink: globus pallidus

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9
Q

what does the internal capule separate posteriorly

A

putamen and thalamus

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10
Q

what are the 3 pairs of nuclei of the basal ganglia

A

putamen, caudate, globus pallidus

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11
Q

putamen and caudate are separated by internal capsule everywhere but

A

rostrally

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12
Q

I am made of two adjacent segments, on external and one internal: (in teh basal ganglia

A

globus pallidus

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13
Q

C shaped nucleus which starts in teh frontal lobe and ends in teh tamporal lobe

A

caudate

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14
Q

which lobes does the caudate nucleus run from and to

A

frontal -> temporal

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15
Q

midbrain is divided into …dorsally and …ventrally

A

tectum dorsal
tegmentum ventral

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16
Q

putamen recives input from (2)

A

primary motor and primary somatosensory cortices

17
Q

what in the midbrain is a reay of teh visual system

A

superior colliculus

18
Q

what is a extrapyramidal tract that runs in parallel to the corticospinal tract

A

rubrospinal

19
Q

which goes first, primary or 2ary motor cortex

A

2ary

20
Q

patellar reflex is a …reflex

A

monosynaptic/proprioceptive

21
Q

major inhib nt in the brain

A

gaba

22
Q

major excitatory nt in the brain

A

glutamate

23
Q

dopamine…(2)

A

mvt regulation, pleasure and reward

24
Q

95% serotonin produced in the

A

gut

25
Q

serotonin…(3)

A

bowel function and appetite, modulation of pain, mood and sensory perception regulation

26
Q

blood supply to basal ganglia mostly from

A

MCA -> lenticulostriate arteries

27
Q

front part of caudate nucleus supplied by

A

ACA -> recurrent artery of Heubner

28
Q

What is the chemical nature of most medium spiny neurons?

A

GABAergic

29
Q

what is the characterisation of parkinson’

A

loss of dopaminergic neurones from the substantia nigra pars compacta (direct pathway). this means the inhibitory indirect pathway becomes dominant, resulting in loss of movement

30
Q

what characterises Huntington’s

A

loss of striatal medium spiny neurones meaning the indirect dopaminergic pathway is loss leading to the direct excitatory pathway becoming dominant -> rigidity

31
Q

at the early stage of huntingtons, waht do you see

A

chorea = hyperexciticity of muscles

32
Q

late stage of hungtingtons

A

loss of all medium spiny neurones so loss of mvt (resembles parkinsons

33
Q

what is BA 1,2,3

A

somatosensory cortex

34
Q

what BA is frontal pole

A

10

35
Q
A