Bacteriology (part2) Flashcards
Known to hemolyze RBC (Red Blood cell)
Streptococci
complete disruption of erythrocytes with clearing of the blood around the bacterial growth
Alpha hemolysis
incomplete lysis of the erythrocytes with reduction of hemoglobin and formation of green pigment
Beta hemolysis
non-hemolytic
Gamma hemolysis
Disease caused by Streptococcus pyogenes
-Cellulitis
-Streptococcal pyoderma
-Necrotizing fasciitis (Streptococcal gangrene)
-Tonsilitis
-Pharyngitis
-Streptococcal toxic shock syndrome
-Scarlet fever
-Rheumatic fever
An acute rapidly spreading infection of the skin and SC tissues. Due to mild trauma, burns, wounds or surgical incisions
Cellulitis
Enters through abrasions and wounds infecting the tissue
Streptococcal pyoderma
Streptococcus pyogenes Usually susceptible to
Bacitracin
β hemolytic streptococci
Streptococcus pyogenes
Streptococcus pyogenes is known as
β-hemolytic Group A streptococci
Transforms plasminogen of human
plasma into plasmin, an active proteolytic enzyme that digests fibrin and other proteins allowing the bacteria to escape from blood clots
Streptokinase (Fibrinolysin)
promotes hemolysis
Hemolysins
small, flattened red patches that develop into oozing pus-filled vesicles on a red base
Impetigo
Tx under streptococcal pyoderma
Tx: Topical mupirocin, oral erythromycin, and dicloxacillin
Extensive and very rapidly spreading necrosis of the skin, tissues and fascia “Flesh-eating bacteria” other name of Group A streptococci that causes necrotizing fasciitis
Necrotizing fasciitis (Streptococcal gangrene)
Tx under Necrotizing fasciitis (Streptococcal gangrene)
Tx: Immediate IV broad-spectrum antimicrobial drugs; removal o
necrotic tissue; clindamycin + PCN
Swollen tonsils, sore throat, difficulty swallowing, tender lymph nodes
Tonsilitis
intense redness and edema of the mucus membranes, with purulent exudates, enlarged and tender lymph nodes and high fever
Pharyngitis
Shock, bacteremia, respiratory failure and multiorgan failure. Tend to occur after minor trauma with several presentations of soft tissue infections
Streptococcal toxic shock syndrome
Scarlet fever is caused by
pyrogenic exotoxins A-C
Diagnosing of scarlet fever
(+) Quellung test and Optochin test
Tx under scarlet fever
Tx: Penicillin (DOC); erythromycin, cephalosporin
Surgery removing tonsil
Tonsillectomy