Bacteriology Part 1 Flashcards
*Define normal flora
Bacteria and fungi that are permanent residents of certain body sites (skin, oropharynx, and vagina)
*Define endemic
Bug specific to a certain region (ex histoplasmosis)
- Define epidemic
Bug that affects a broader population (ex Ebola)
- Define Pandemic
Bug that spans continents; worldwide (HIV; black plague)
*Define subclinical
Pathogen/disease is present but does not present with any symptoms (ex chlamydia)
*Define Latent
Bug that remains in an inactive or hidden phase (ex herpes simplex)
*What is the source of exotoxins?
G+ and G- bacteremia
primarily gram + bacteria
- a. What is the source of endotoxins
b. what are the symptoms?
a. G-Rods and Cocci (gram- bacteria)
b. Fever, shock, general sympt
- Name 4 main portals for transmission
GI tract, Genital tract, skin, Respiratory tract
- Name examples of Gram + cocci
S. Pneumoniae, S. Pyogenes, S. aureus
- Name examples of Gram - cocci
N. meningitis
- a) What organism causes tetanus toxin
b) what disease is caused
a) Clostridium tetani
b) lockjaw
- a) What organism causes botulinum toxin
b) What disease is caused
a) Clostridium botulinum
b) Botulism–> parylasis of muscles
- What organism causes Exotoxin A
Clostridium difficile
- What symptom does Clostridium difficile cause?
Watery diarrhea
- What organism causes alpha toxin
Clostridium perfringens
*Which action does Clostridium perfringens lead to?
Wide spread cell death
*What organism causes anthrax?
Bacillus anthracis
- What is a symptom of anthrax?
Tissue edema (of lungs)
- What organism causes toxic shock syndrome?
Staphylococcus aureus
*What organism causes erythrogenic toxin?
Streptococcus pyogenes
- What disease is streptococcus pyogenes associated with?
Scarlet fever (characteristic rash)
- What organism is associated with heat-liable enterotoxin?
E. coli
*What disorder is caused by E-coli
Watery, nonbloody diarrhea
- What organism is associated with Verotoxin
E. Coli O157: H7
- a) What is the source of E. coli O157: H7?
b) what symptom results?
a) Undercooked hamburger
b) Bloody diarrhea
*What symptom does cholerae enterotoxin cause?
Diarrhea
What is the difference between coagulase + and coagulase -
Coagulase + forms a clot due to the conversion of fibrogenin to fibrin; coagulase - does not form a clot
- What are the 3 types of staphylococcus?
Staphylococcus aureus, staphylococcus epidermidis, and staphylococcus saprophyticus
What disorder is staphylococcus aureus associated with?
ABSCESSES, Endocarditis, & Osteomyelitis
What disorder is staphylococcus epidermidis associated with?
Endocarditis
What disorder is staphylococcus saprophyticus associated with?
UTIs
- a)What symptoms do enterotoxins cause?
b) what is often associated?
a) Vomiting and watery, nonbloody diarrhea
b) FOOD POISONING
*What disorder is associated with Exfoliatin (type of toxin)
Scalded skin syndrome
*What symptoms are associated with Toxic Shock Syndrome?
Fever, hypotension, rash
What smear do Gram + cocci present with?
grape-like clusters
*What disease is associated with streptococcus?
Pharyngitis
How are spherical cocci usually arranged?
Chains or pairs
*What is associated with Erythrogenic toxin?
Scarlet fever
- What is Streptolysin O associated with?
Rheumatic fever
- What is Pyrogenis exotoxin A associated with?
Super antigen
- What is associated with Exotoxin B?
Necrotizing fascitis
What is streptococcus bovis endocarditis associated with?
Colon cancer
*What disease is elevated ASO (antistreptylocin) titers associated with?
Rheumatic fever
What is the shape of the streptococcus pneumonia bug?
Lancet shaped cocci (comma) and arranged in pairs (diplococci)
What is streptoccus pneumoniae associated with?
Rusty color sputum
*What are the 2 main types of gram- cocci?
Neisseria meningitis and Neisseria gonorrhea
*What disease is neisseria meningitis associated with?
Meningitis and meningitiscoccemia
- What disease is neisseria gonorrhoeae associated with?
Gonorrhea and neonatal conjunctivitis
What shape do Neisseria have?
Gram- rods resembling kidney beans