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Bacteriology > Bacterio6 > Flashcards

Bacterio6 Flashcards

1
Q

Salmonella typhimurium causes only ……

A

Gastroenteritis

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2
Q

Salmonella typhimurium have a (broad/narrow) host range

A

Broad

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3
Q

Salmonella typhi lost the …. genes and became host……(narrow or broad), it’s (imvasive or not)……

A

Generalist genes
Host restricted (narrow)
Invasive

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4
Q

Salmonella dublin and cholerasuis are host …….( restricted or adapted), and they are part of …….. of cow and pig respectively.

A

Adapted

NF

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5
Q

Typhoid fever aka….. fever, the specific cell for salmonella infection is the ….. cell crossing it by ……., this will cause hyperplasia of ……..

A

Enteric fever
M cell
Transcytosis
Peyer’s patches

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6
Q

T or F

V.cholera have an inoculum size less than salmonella

A

False

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7
Q

Salmonella affects other organs: ……. and …… , where in the latter it can remain dormant but still can be transmitted

A

Liver and gallbladder

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8
Q

……. appearance on skin is caused by salmonella

A

Rose spots

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9
Q

T or F

We can rely on the appearance of rose spots to diagnose salmonella

A

False

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10
Q

T or F

Salmonella can cause perforation

A

True

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11
Q

How to treat salmonella patients?

A

Ceftriaxone IM

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12
Q

Dessert🧇

The diarrhea in case of enteric fever is called….

A

Pea-soap diarrhea🥲

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13
Q

Sickle cell anemia patients have a higher risk of developing…….. after infection with salmonella

A

Osteomyelitis

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14
Q

T or F

Salmonella can cause constipation

A

True

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15
Q

T or F

Salmonella can cause leukopenia

A

True

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16
Q

Salmonellosis aka….. is caused by two salmonella families …… and……, characterized by …… diarrhea,where we (should/not) give antibiotics because…….

A

Enterocolitis
Typhimurium and enteritidis
Profuse diarrhea
Shouldn’t give because this will increase carriage time

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17
Q

There are 3 types of salmonella vaccine list them

A

Killed vaccine heated
Live (attenuated) Ty21A
Vi vaccine
(killed, attenuated and polysaccharide)

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18
Q

Campylobacter jejuni have a ……. appearance, and ….. flagella, grows on …… medium, grows on (high/low)…… temperature and (aerobic or microaerophilic)…..
The inoculum of campy jejuni is ……

A
  • sea gull apearance or comma
  • 2 flagella each on one side (bipolar)
  • skirrow (vancomycin,polymixin and trimethoprim)
  • high (42)
  • microaerophilic
  • 1000
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19
Q

Source of infection of campylobacter jejuni:….

A

Poultry (meat - chicken and milk)

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20
Q

Symptoms of campylobacter jejuni:

A 
Nausea
Diarrhea (often bloody)
Vomiting
Fever
Most common cause of gastroenteritis in US
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21
Q

T or F

Campylobacter jejuni are not invasive

A

False

Can cause transient bacterimia

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22
Q

…… can cause reactive arthritis (reiter’s syndrome)

A

Campylobacter fetus

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23
Q

T or F

Reiter’s syndrome is cause by campylobacter fetus after bacterimia

A

False

It’s immunopathological ( cross reaction)

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24
Q

T or F

Campylobacter fetus can cause bacterimia especially immunocompromised patients

A

True

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25
Q

Tx of vibrio vulnificus

A

Doxycycline

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26
Q

Vibrio …… can cause ——- and ——– skin lesions, MR is ——-

A

Vulnificus
Septicimia
Metastasic
50%

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27
Q

T or F

Vibrio paraheamolyticus and vulnificus infections are caused mainly by sea food

A

True

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28
Q

T or F

Vibrio vulnificus causes desentry like syndrome

A

False

29
Q

T or F

IP for vibrio para. Is long

A

False

Short

30
Q

T or F

Vibrio parah. Causes a severe gastroenteritis

A

False

Self limited

31
Q

T or F

Vibrio vulnificus can be caused only through GI

A 
False
Direct contact ( open wounds + sea water)
32
Q

Mode of transmission of V.cholera

A

Fecal oral

33
Q

T or F

V.cholera is acid labile

A

True

Grows in basic med ( 8.5-9.5 )

34
Q

V.cholera survives the acidic medium or the stomach by …..

A

Buffering effect ( usually present with other substances(eg. Water…))

35
Q 
V cholera charac:
...... shape
Ox(.....) Cat (...)
Grows on ...... agar
Causes ........ stool
...... flagella
(Halophilic / thermophilic)
A 
Comma
\+  +
TCBS
Rice watery
1 flagellum
Halophilic
36
Q

T or F

GM1 is the receptor for V.cholera

A

False

V.cholera toxin

37
Q

T or F

Tx of v.cholera is tertacycline

A

False

38
Q

Prophylaxis for V.cholera

A

Tetracycline

Azithromycin or erythromycin for children and pregos

39
Q

Vax for V cholera is …… and induces (permanent/not)…… immunity

A

Capsular

Not permanent

40
Q

Modes of transmission of shigella

A

Fecal oral route

MSM ( man having sex with a man)

41
Q

Shigella causes ……. colitis

A

Inflammatory

42
Q

Shigella is (invasive/not)……, releases …… which is a ….. mediated toxin, this toxin inhibits …….. synthesis

A

Invasive
Shiga toxin
Chromosomally
Protein

43
Q

T or F

Salmonella is the number 1 cause of osteomyelitis in sickle cell anemia patients

A

True

44
Q

Shigella have (high/low) …….. inoculum,
In immunocompromised patients it causes :
1-
2-
3-
4-

A 
Low
Bacterimia
Fever
Seizure
Rectal prolapse
45
Q

Tx for shigella

A

Ceftriaxone

46
Q

T or F

Shigella have low incubation period

A

False

No IP

47
Q

T or F

Shigella is a STI

A

False

48
Q

Shigella causes ……. due to neurotoxicity

A

Tenesmus

49
Q

T or F

In shigella infections we give anti-diarrheal medications

A

False

50
Q

Shigella vaccine is called….

A

No vaccine for shigella

51
Q

Tx of H.pylori

A

Triple therapy : proton pump inhibitor,amoxicillin and clarithromycin

Quadriple : proton pump inhibitor, tertracycline, metronidazole and bismuth

52
Q

List the tests we can use to detect H.pylori

A

Invasive:
Gastroscopy

Non-invasive:
Serology (IgGs)
Stool antigen test
Urea breath test

53
Q

T or F

Taking proton pump inhibitors can give a false positive result on urea breath test

A

False

False negative

54
Q

H.pylori are urease (—-) , (motile/non)——-, it’s considered as a lifelong (colonization/disease).——– and secretes exotoxins for —— attraction

A

Urease +
Motile
Colonization
PMN

55
Q

H.pylori causes :
1——-
2——–
3——– in MALT

A

Antral gastritis
Peptic ulcer disease (PUD)
Adenocarcinoma

56
Q

Symptoms caused by H.pylori
1——-
2——-
3——-

A

Bloating
Decreased appetite
Bad breath odor

57
Q

How H.pylori remove the mucus allowing the gastric acid to penetrate the tissue and make ulcers?

A

Binds by adhesins
CagA and Vac A
Secreting urease that will form ammonia
Ammonia will make the neutralize the medium

58
Q

Virulence factor of H.pylori:
1—-
2—–
3——–

A

1-Flagella to get into mucus
2-Urease to release ammonia and neutralize the medium
3- CagA and VacA

59
Q

List the clues and symptoms of enteric fever

A
  • hepatic necrosis (after bacteremia)
  • gallbladder inflammation (after bacteremia)
  • perforation
  • septicimia and sepsis
  • hallucination because of fever
  • clues : constipation and leukopenia
60
Q

In HIV patients typhimurium can cause ——– this show that the infection depends on —–/—– interaction, in elderly it can cause —— absceses and ——–

A

Enteric fever
Germ/host
Splenic
Aortitis

61
Q

Salmonella can be transmitted by —— animals like ———

A

Exotic

Lizards, turturles and caoti

62
Q

T or F

Gram + can cause sepsis by it’s exotoxin

A

False

By TA

63
Q

T or F

After shigella infection we have temporary immunity against it

A

False

Premanent

64
Q

Classic and eltor cholera are caused by ——- serotype

A

O1

65
Q

T or F

Vibrio parahe. Can cause fever

A

True

66
Q

Diseases caused by sea food (vibrio) are mainly due to ——-

A

Global warming

67
Q

Human are the only hosts for——-

A

Shigella

68
Q

T or F

Shigella is invasive and causes bacteremia in immunocompetwnt patients

A

False

No bacteremia

69
Q

T or F

Campylobacter jejuni can cause sepsis

A

False

Only transient bacteremia

Bacteriology (10 decks)

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