Bacterio3 Flashcards

1
Q

Cutibacterium acnes is a gram …. bacterium ,…….(aerobic/anaerobic)that cause the formation of ….

A

Positive
Anaerobe
Acne vulgaris

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2
Q

T or F

Comedones are lesions on skin caused by cutibacteria (blackheads or white heads)

A

True

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3
Q

Cutibacteria multiplies in …. gland and blocks the pore

A

Sebaceous

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4
Q

How to treat acne?

A

Doxycycline

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5
Q

Corynebacteria diphtheriae is from a family called … some are from … and mostly non pathogenic

A

Diphtheroids

NF

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6
Q

The pathogenic form of diphtheriae is gram …,(motile/non),(sporeforming/non) that grows on ……..medium

A

Positive
Non-motile
Non spore forming
Tellurite Blood

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7
Q

Tellurite medium makes the colony appears …. because of the …. granules present in diphtheria

A
Black
Metachromatic granules (ppi)
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8
Q

T or F

Upon gram staining corynebacteria appears like a chinese letter at the edge of the culture and drumstick in the middle.

A

False

Reversed

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9
Q

T or F

Diphtheria is a respiratory infection but also can cause skin infections trasmitted by contact.

A

True

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10
Q

T or F

Diphtheria can cause diseases even if it didn’t secrete diphtheria toxin

A

False

It should release it to cause the disease

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11
Q

Tor F

Diphtheria toxin affects the nucleic acid synthesis in the host cell.

A

False

Protein synthesis

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12
Q

Diphtheria infected people suffers from …. neck and …..-membrane that have white-greyish appearance
We (should/shouldn’t) pull it out.

A

Bull
Pseudo-membrane
Shouldn’t because the toxin will spread and may cause death

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13
Q

How to treat diphtheria ?

A

Penicillin G+ Anti-diphtheria toxin (IV or IM)

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14
Q

Diphtheria toxin can cause … paralysis and this will lead to…..

A

Soft palate

Suffocation or aspiration

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15
Q

Worst case scenario, Diphtheria toxin may cause myocarditis and consequently ……

A

Heart failure

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16
Q

Skin diphtheria sits on skin that has predisposition for…..

A

Wounds

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17
Q

…… is a test used to identify if the diphtheria is toxigenic or not

A

Elek plate

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18
Q

Listeria monocytogenes (anaerobic/facultative anaerobes)….. ,(extracellular/intracellular)…. and (motile/nonmotile)

A

Fac anaerobes
Fac Intracellular
Motilee (to be seen later)

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19
Q

Listeria has 3 modes of transmission :
1-
2-
3-

A

1- food by ingestion

2- trasmit it transplacentally from mother to child (like agalactiae)
3- during delivery (like agalactiae)

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20
Q

…… enrichment medium is used to detect the presence of Listeria monocytogenes

A

Cold enrichment medium (4 C)

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21
Q

After primary bacterimia , Listeria could reach the …..or ….
Thus it’s an (invasive/non-invasive)….. bacteria

A

Brain or placenta

Invasive

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22
Q

Treatment of Listeria monocytogenes

A

Ampicillin

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23
Q
High risk group of infection with LM:
1-
2-
3-
4-
A

1- immunocompromised ( have higher risk of all infections)
2- pregnant woman after eating undercooked food
3- infants (transplacentally or vaginal during delivery)
4- elderly

24
Q

Non specific Complications cause by LM:

A

1- fever
2- myalgia
3- arthralgia

Because we see them in other diseases like covid

25
Q

Specific complication caused by LM:

A

1-septicimia
2-meningitis (it can reach the brain)
3- self limited gastroenteritis

26
Q

….. is a term used when we suffer from gastroenteritis followed by recovering.

A

Listeriosis

27
Q

When a baby is infected with LM , he is said to be ……. and thus inducing …….
This case is called…

A

Septic
Granulomatosis
Granulomatosis infantiseptica

28
Q

T or F

LM is always motile because it has many flagella made from flagellin and it’s peritrichous

A

False
Not always motile at some point it uses the actin of the host cell and make flagella from those actin filaments. And become peritrichous

29
Q

LM secretes ….. as a virulence factor (exotoxin) to escape the vacuolar lysis

A

Listeriolysin O

30
Q

List the modes of transmission of bacillus anthracis

A

1- by contact
2- by inhalation (woolsorter’s disease)
3- by ingestion (causes septic kind of diarrhea)

31
Q

The capsule of bacillus anthacis is made up of …….

A

Polypeptides

32
Q

The anthrax toxin is made up of ……. parts, each part is encoded by specific gene each present on a….

A

3

Plasmid (we have 3 plasmids)

33
Q

The 3 parts of anthrax toxinare called,……,……,….

A

PA
LF
EF

34
Q

List the role of each of the following parts:
PA
LF
EF

A

PA is the protective antigen that binds first and attracts the other 2
LF lethal factor for killing
EF edema factor for swelling

35
Q

The colony of bacillus anthracis in a culture media adopts the shape of …..

A

Medusa’s head

36
Q
Skin anthrax can consequently leads to :
1-
2-
3-
4-
A

1-papule (elevated skin)
2-vesicle (may)
3-pustule(pus)
4-necrotic lesion

37
Q

Regarding diphtheria, it’s not toxigenic unless…….

A

It was infected by a bacteriophage having diphtheria toxin gene

38
Q

T or F

Regarding LM, it’s a bimodal bacteria.

A

Trueee

39
Q

Bacillus anthracis is a gram…. bacterium, (sporeforming/not)…. and (invasive/not)….

A

Positive
Spore forming
Not Invasive

40
Q

Regarding black eschar caused by ……, the pustule is said to be (benign/malignant)…….

A

Bacillus anthracis

Malignant

41
Q

……. edema is the edema that surrounds the eschar, it contains viscous fluids rich in …. and have a ….. color.

A

Gelatinous edema
Proteins
Red

42
Q

Mediastinitis is a clinical case that is caused by …… bacteria, after water and blood in the mediastinum compress on the….

A

Bacillus anthracis

Veins

43
Q

T or F

Human are accidental hosts for bacillus anthracis

A

True

44
Q

T or F

Antrax can cause hemorrhagic diarrhea

A

True

45
Q

Bacillus cerues and anthracis are gram… bacteria and (anaerobes/aerobic)…

A

Positive

Aerobic

46
Q

Bacillus cereus is a (noninvasive/invasive) bacteria…that causes …. that is not an infection

A

Not invasive

Food poisoning

47
Q

We have 2 strains of cereus:
1- …… causes vomiting
2- ……. causes diarrhea

A

Emetic

Diarrheal

48
Q

Emetic strain works on …. of the hypothalamus DIRECTLY and it’s found on starchy food left at room temperature for a long period of time where it’s toxin becomes heat…, it’s incubation period is …. and lasts for…

A

Vomiting center
Stable
Less than 6 hours
1 or 2 days

49
Q

Diarrheal strain have (bigger/smaller) … IP , it’s poison is heat ….with an inoculum size …. to cause poisoning with symptoms like …. and…..

A

Bigger (up to 6)
Labile
10^8
Stomach ache and diarrhea

50
Q

Bacillus can cause swelling of the eyeball , this case is called…… and may consequently leads to irreversible ……. because it can also affects the retina.

A

Panophthalmitis

Blindness

51
Q

T ro F

Diphtheria can cause toxemia

A

True

52
Q

DT can lead to paralysis of ——– and —— nerves

A

Heart

Adrenal

53
Q

Ip for DT

A

5-10 days (average 1week)

54
Q

Outcomes of LM

A

Like strep B
Abortion or still birth whether early or late
Pueperal sepsis on woman

55
Q

Ip for LM

A

1-90 days

56
Q

T or F

A patient can die from skin anthrax

A

True

57
Q

T or F

Anthrax can cause hemorrhagic diarrhea but not a septic one

A

False

Can cause both