Bacterial Zoonoses Flashcards
Leptospira
- Hawaii
- Urine contaminated water/post natural disaster
Flu-like sx
Conjunctival suffusions
Weil syndrome:
- jaundice
- renal dysfunction (inc creatinine)
Tularemia
Francisella tularensis
Ticks and rabbits
G-
facultative intracellular
can be aerosolized
Ulceroglandular. lesion is the entry site – lymphadenitis and ulceration.
Tx: Strepto or Genta
Brucellosis
G- coccobacilli
facultative intracellular - grows in macs
farm animals
Unpasteurized milk/dairy
“Undulant fever”, anorexia, arthralgia, chronic.
Systemic: GI, resp, bones
reticuloendothelial spread – liver and spleen
BM culture
Tx: Combination therapy : Doxy and rifampin
Yersinia pestis
Plague
“Safety pin” appearance
Rodents and fleas
Xenopsylla chepsis: oriental rat flea
Buboes - enlarged LNs
Tx: Strepto and TCN
Vaccinate pets
Coxiella burnettii
Q fever
pleomorphic rod, G-
strict intracellular
Cattle, sheep, goats, dogs
unpasteurized dairy products
inhale birthing fluid aerosole/dust.. Direct expo to tissues
No rash!
Pneumo and fever, HEPATITIS
chronic - endocarditis
Serology:
acute: Phase II Ag (IgM, IgG)
chronic: Phase I and II ab. I»II
Bartonella henselae
Cats and fleas
Cat scratch disease - immunoCOMPETENT
- Children
- Chronic regional lymphadenopathy (sentinal node)
may see prolonged fever w/ no source
Bacillary angiomatosis - ImmunoCOMPROMISED
IgG titer
self-limited. Use Azithro if Tx needed
Avoid surgical drainage!
Animal bite
mouth flora
cats more so than dogs
puncture wounds.
Irrigate and debridement of the wound
don’t dose!
Pasteurella
Fermentative, G- coccobacilli
P. multocida - cat saliva
P. canis - dog saliva
rapid dev of cellulitis after bites (w/in 24 hrs)
osteomyelitis also possible
Tx: PCN w/ beta- lactamase (Amoxicillin-clauvulanic)
Capnocytophaga canimorsus
cats/dogs
G- fusiform bacilli
Eikenella Corrodens
Human bites/fist fights
found in human oropharynx
G- rods
HACEK
Corrodes agar, bleach smell
