Bacterial Genome Flashcards

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1
Q

Genome

A

conserved core gene pool + a flexible gene pool

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2
Q

Genome’s conserved core gene pool

A

generally concerned with basic cellular function/housekeeping genes (GC rich content)

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3
Q

Genome’s flexible gene pool

A

encode for additional function that are not essential for bacterial growth but are advantageous, can be transferred via HGT

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4
Q

Functional gene pool consists of

A

Genomic islands: mobile genetic elements >10kb
Genomic islets: mobile genetic elements <10kb
Prophages
Plasmids

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5
Q

Genomic Island

A

large gene chunk that carries genes for adaptation, signs of mobile elements (phage or plasmid or tRNA), unstable, abnormal CG%, etc

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6
Q

Genomic island advantage

A

confers survival of organism under adverse conditions

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7
Q

Pathogenicity Island

A

genomic island associated with pathogenesis

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8
Q

Antibiotic Resistance Island

A

genomic island containing antibiotic resistant genes

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