B cell: FC receptors Flashcards
1
Q
What do FC receptors bind to?
A
FC region of Ig molecules
2
Q
Where are FC receptors found?
A
Immune cells
NK cells
Mast cells
Neutrophils
Eosinophils
3
Q
Specific to?
A
Antibody subclasses and isotypes
4
Q
Phagocytes
A
use FC receptors internalize antigen
5
Q
Natural Killer Cell
A
Kill target cells
6
Q
How do NK cells kill target cells?
A
ADCC
Antibody dependent cell mediated cytotoxicity
FC receptor on NK Cell recognise bound antibody
7
Q
What signal given to kill target cell by NK
A
Cross linking of FC receptors
8
Q
Kill
A
APOPTOSIS