B + a1 Blockers/a1 blocker/a2 blocker----EXAM2 Flashcards
3 rd gen nonselective
Dec cont and HR
Vasodilate (a1)
Carvedilol,
Labetalol
4th gen, b1 selective
Nebivolol
IND
Hypertension, compensated heard failure
Carvedilol
Int (carvedilol)
Ride blood in ca ci
Rifampin Digoxin Blood pressure meds Ca ch blockers Cimetidine (inhi elimination)
INT
Rifampin Digoxin Blood pressure meds Ca ch blockers Cimetidine (inhi elimination)
Carvedilol
AD
Sexual dysfunction, depression, dyslipidemia, sleep disturb, bradycardia, hypotension, dizziness, fatigue
Carvedilol
Labetalol
IND (Labetalol)
Hypertension(oral), hypertensive emergemcies (IV),
Hypertension due to pheochromocytoma
Acute aortic disection
IND
Hypertension(oral), hypertensive emergemcies (IV),
Hypertension due to pheochromocytoma
Acute aortic disection
Labetalol
INt (labetalol)
BP meds, cimetidine(inhi elimination)
IV labetalol
More b blocking activity than a blocking activity(7:1)
Oral-> 3:1=b:a
B + a1 blockers
Car lab navi
Carvedilol
Labetalol
Nebivolol
a 1 blocker
Vasodilate- inhi catecholamine (lower BP)
Dec afterload of heart,
Dec peripheral vascular resistance
a1 blocker
Aldo 에서 Tam나는 The Prada 신발 만듬
Alfuzosin- prostate selective for BPH
Doxazosin
Tamsulosin- prostate sele for BPH
Terazosin
Prazosin
IND
a1 blocker
Hypertension,
Peripheral vascular ds (claudication)
Used in heart failure secondary to development of tachyphylaxis (not primary)
Benign prostate hypertrophy- only for tamsulosin and alfuzosin
INT
a1 blocker
Verapamil, BP meds, NSAID
Verapamil- inc prazosin drug level