Autopsy Flashcards

1
Q

Implicit questions asked from autopsy

A
  • were we right

- did we miss something

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2
Q

Giovanni Battista Morgagni - Padua

A
  • out with Galen’s evil humours, in with structure/function
  • 60 years careful correlation of clinical symptoms & anatomic findings
  • 1700s
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3
Q

Karl Rokitansky - Vienna

A
  • one of the first PATHOLOGISTS: gross tissue morphology became basis of medicine
  • pathologic anatomy to clinical abnormalities
  • 70,000 autopsies!!!!!
  • 1800s
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4
Q

Rudolph Virchow - Berlin

A
  • narrowed gross tissue morphology to separate organs
  • cellular pathology as the basis of medicine
  • late 1800s
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5
Q

William Osler

A
  • wished he could see his autopsy
  • what to why
  • 1849-1919
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6
Q

Richard Cabot

A
  • landmark JAMA paper 1912

- couple quotes

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7
Q

1912 Cabot listed common diseases inaccessible to diagnosis

A
Diabetes Mellitus - 95%
Typhoid - 92%
Aortic Regurgitation - 84%
Cancer of Colon - 74%
Lobar Pneumonia - 74%
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8
Q

Diseases discovered or clarified via autopsies in 20th century

A
  • coronary artery atherosclerosis & thrombosis, angina pectoris, MIs
  • congenital heart malfomations
  • cystic fibrosis
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9
Q

Diseases discovered or clarified via autopsies late 20th century

A

AIDs, hantavirus pulmonary syndrome, dementias, inhalation diseases of lungs, creutzfeldt-jakob disease, infectious complications of drug therapies, hospital-acquired infections

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10
Q

Why autopsies

A
  • medical education (now rare)
  • quality assessment of diagnosis and treatment
  • risk management
  • public health
  • family
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11
Q

UIHC QA program from autopsies

A
  • list major validated/refined diagnoses
  • list major clinicopathologic discrepancies
  • list major unexpected findings
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12
Q

why decline of autopsy

A
  • payment: hospitals & pathologists unpaid under fee for service model
  • public perception
  • clinical medicine: overconfidence & litigation
  • medical education
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13
Q

autopsy decline statistics

A

1950s:>50%
UIHC: 25%
US:

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14
Q

when can autopsies be performed

A
  • after obtaining informed consent from family, process is aprt of physician family communication
  • ME cases don’t need consent
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15
Q

define autopsy

A

autopsy - to see for oneself

postmortem - after death

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