Autonomic NS Flashcards

1
Q

ANS classification

A
  1. by anatomy

2. by neurotransmitter used

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2
Q

sympathetic

A

thoracolumbar

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3
Q

parasympathetic

A

craniosacral CN: 3,7, 9,10

S 2,3,4

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4
Q

ANS neuronal breakdown

A

pre/postganglionic fibers

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5
Q

sympathetic fibers synapse on

A

sympathetic ganglion chain–short pre-long post

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6
Q

uppermost sympathetic chain ganglia

A

stelate (star shapped) ganglia–largest

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7
Q

white rami

A

myelenated–pre-ganglionic fibers

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8
Q

gray rami

A

unmyelenated–post-ganglionic fibers

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9
Q

some efferent fibers don’t synapse in sympathetic ganglia, they

A

synapse in colateral ganglion (celiac, and inferio/ superior mesenteric fibers)

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10
Q

Parasympathetic NS

A

preganglionic (long pre-gang) leave brainstem or sacrum and synapse very near target site (short post-ganglionic)

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11
Q

2 nt’s in autonomic NS

A
  1. Acetocholine (cholinergic synapse)

2. Norepinephrin (adrenergic synapse)

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12
Q

Break down epi/norepi

A

MAO monoamine oxidase

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13
Q

ACh receptors

cholinergic synapses

A
  1. Nicotinic cholinergic: more reactive to nicotine–@ neuromuscular junctions, all autonomic ganglion, and adrenal mudella (understandable because no ganglionic synapse)
  2. Muscarinic
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14
Q

Muscarinic cholinergic receptors

A

5 types or receptors–result depends on end-organ body-wide

study basic result

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15
Q

M2 Muscarinic cholinergic receptors

A

(mostly parasympathetic) lower heart rate, pupillary constriction, GI contraction, bronchoconstriction, ^ erection,

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16
Q

Autonomic NS by anatomy

A

sym: short pre, long post (exception adrenal–leave SC no synapse until adrenal cortex)
para: long pre, short post

17
Q

Adrenergic receptors

A
1. Alpha
      Alpha 1 
      Alpha 2
2. Beta 
      Beta 1
      Beta 2
18
Q

Important Alpha adrenergic receptor clinically

A

Alpha 1 – vasoconstriction, pupil dialation

19
Q

Important Beta adrenergic receptor clinically for heart

A

Beta 1 – heart (beta blockers)

20
Q

Important Beta adrenergic receptor clinically for lungs

A

Beta 2 – relax lungs–blocks bronchodilation–beta stimulation

21
Q

glycogen broken down into

A

glucose by liver

22
Q

Atenalol

A

more Beta 1 effect–used to be non-selective–now they’re selective for Beta 1 or 2

23
Q

mostly excitatory but sometimes inhibitory

A

sympathetic NS

24
Q

cholinergic activation mostly

A

all parasympathetci pre/post ganglionic receptors are cholinergic, but not all cholinergic receptors are parasympathetic

25
Q

cilliary muscles

A

parasympathetic–cholinergic–stretch lens

26
Q

anticholinergic side effects

A

atrophin–dry mouth, blurry vision (aka parasympatholitic w/ exceptions in parasympathetic system)

27
Q

sympathomimetic

A

drug that mimics sympathetic system

28
Q

Sympatholitic

A

lyse (anti-sympathetic drug)

29
Q

small pupils

A

myosis

30
Q

decreased sweating

A

anhydrosis

31
Q

horner’s syndrom

A
SPAM
Sunken eyeballs
Ptosis
Anhydrosis
Miosis
32
Q

All postganglionic sympathetic nerves secrete norepinephrine except

A

1 sweat glands
2 piloerector muscles
3 some blood vessels

Secrete ACh

33
Q

Blood vessels solely controlled by

A

Sympathetic NS– constriction only