Autonomic NS Flashcards
ANS classification
- by anatomy
2. by neurotransmitter used
sympathetic
thoracolumbar
parasympathetic
craniosacral CN: 3,7, 9,10
S 2,3,4
ANS neuronal breakdown
pre/postganglionic fibers
sympathetic fibers synapse on
sympathetic ganglion chain–short pre-long post
uppermost sympathetic chain ganglia
stelate (star shapped) ganglia–largest
white rami
myelenated–pre-ganglionic fibers
gray rami
unmyelenated–post-ganglionic fibers
some efferent fibers don’t synapse in sympathetic ganglia, they
synapse in colateral ganglion (celiac, and inferio/ superior mesenteric fibers)
Parasympathetic NS
preganglionic (long pre-gang) leave brainstem or sacrum and synapse very near target site (short post-ganglionic)
2 nt’s in autonomic NS
- Acetocholine (cholinergic synapse)
2. Norepinephrin (adrenergic synapse)
Break down epi/norepi
MAO monoamine oxidase
ACh receptors
cholinergic synapses
- Nicotinic cholinergic: more reactive to nicotine–@ neuromuscular junctions, all autonomic ganglion, and adrenal mudella (understandable because no ganglionic synapse)
- Muscarinic
Muscarinic cholinergic receptors
5 types or receptors–result depends on end-organ body-wide
study basic result
M2 Muscarinic cholinergic receptors
(mostly parasympathetic) lower heart rate, pupillary constriction, GI contraction, bronchoconstriction, ^ erection,