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FF2 Exam 1 > Autonomic Nervous System > Flashcards

Autonomic Nervous System Flashcards

1
Q

What are 2 anatomical components of the PNS?

A

ganglia and nerves

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2
Q

What are the 2 divisions of the afferent part of the PNS?

A
  • Somatosensory
  • Special sensory
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3
Q

Which division of the motor aspect of the PNS regulates blood vessels, glands and organs?

A

Autonomic or visceral?

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4
Q

Sympathetic is _______________(catabolic/anabolic)

A

Catabolic (increases contraction)

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5
Q

Where are the cell bodies located in the spinal cord?

A

Intermediolateral grey column

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6
Q

The anabolic ANS is described as ____________.

A

Parasympathetic

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7
Q

Which flow is in the sympathetic ANS?

A

Thoracolumbar flow

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8
Q

The craniosacral flow involves which cranial and sacral nerves?

A

Cranial: X (vagus)
Sacral: pelvic

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9
Q

Which neurotransmitter is in the parasympathetic ANS?

A

ACh

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10
Q

NE/E is part of which ANS division?

A

Sympathethic

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11
Q

What is the relay station outside of CNS?

A

A ganglion

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12
Q

Which axons are longer in the sympathetic ANS? (Pre/Post)

A

Post-ganglionic

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13
Q

Which axons release ACh in the sympathetic ANS?

A

Pre-ganglionic

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14
Q

What are the catecholamines?

A

Epinephrine and Norepinephrine

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15
Q

List the neurotransmitter released by pre and the post ganglionic axons in the parasympathetic NS

A

Both release ACh

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16
Q

Define the limits of the vagosympathetic trunk

A

C1-C4

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17
Q

What CN are involved in the craniosacral flow of the vagosympathetic trunk?

A

CN 3, 7, 9, 10

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18
Q

What CN are involved in the craniosacral flow of the vagosympathetic trunk?

A

CN 3, 7, 9, 10

19
Q

List the 3 structures involved in the sympathetic NS ?

A
  • vertebral n
  • hypogastric n
  • pelvic plexus
20
Q

What is the type of response that ACh is related to?

A

Cholinergenic

21
Q

What is the enzyme that breaks down ACh and where does it do it?

A

Acetylcholinesterase (AChE) at the synaptic cleft

22
Q

List the 2 receptors that bind ACh

A
  • Nicotinic
  • Muscarinic
23
Q

Describe the Nicotinic receptor (type, locations)

A
  • somatic and ionotropic
  • muscles in the NMJ
24
Q

Which ACh receptor is autonomic, metabotropic and innervates glands?

A

Muscarinic

25
Q

Which Muscarinic receptor is in sweat /salivary glands?

A

M1

26
Q

ACh M2 Receptor is located in __________

A

The heart

27
Q

Which M ACh receptor is in the sphincters and GIT?

A

M3

28
Q

What are 2 ways that one can regulate the activity of ACh?

A
  • Clear AChE
  • Internalize the cholinergenic receptors
29
Q

List 3 types of substances that can target the cholinergenic receptor

A
  • agonist
  • antagonist
  • Synergistic (assists activation)
30
Q

Neostigme is an example of and what does it treat

A

AChE inhibitor - muscle strengthener
Tx for myasthenia gravis

31
Q

What can block ACh release that causes flaccid paralysis?

A

Botulinum toxins

32
Q

What can Turbocurarine do ?

A

Block NMJ receptors (myorelaxant)

33
Q

Give an example of a Muscarinic receptor antagonist

A

Atropine

34
Q

What can atropine treat?

A

Glaucoma

35
Q

What are the 3 receptor types that Norepinephrine ?

A
  • alpha - 1
  • alpha -2
  • Beta
36
Q

What type of receptor are the NE ?

A

GCPR

37
Q

Are NE receptors post or pre ganglionic?

A

Post

38
Q

Are NE receptors post or pre ganglionic?

A

Post

39
Q

Is NE short or half life?

A

Long Half life

40
Q

Is epinephrine short or long half life?

A

Short

41
Q

What are the 2 enzymes that break down monoamine oxidase?

A
  • Monoamine oxidase (MOA)
  • Catechol-O-methyl transferase
42
Q

Which NE enzyme is located in the synaptic cleft?

A

MAO

43
Q

Where is COMT (NE enzyme) located?

A

Pre - synaptic ganglion (axons)

FF2 Exam 1 (6 decks)

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