Autonomic nervous system Flashcards

1
Q

What is the autonomic nervous system

A

part of the peripheral nervous system involved with involuntary motor control of smooth muscle and glands

Sympathetic ANS: “fight or flight” response
Parasympathetic ANS: “rest and digest” response

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2
Q

Where does the sympathetic nervous system arise from

A

the thoracic and lumbar regions

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3
Q

where does the parasympathetic nervous system arise from

A

the cranial nerves (brainstem) and the sacral region (pelvic splanchnic nerves- S2-S4 )

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4
Q

How are the sphlanchnic nerves involved with the autonomic nervous system

A

greater splanchnic - T5-T9 –> coeliac plexus –> sympatehtic innervation of the foregut

lesser splanchnic T10-T11 –> superior mesenteric plexus –> sympathetic innervation of the midgut

least splanchnic T12 –> inferior mesenteric plexus –> sympathetic innervation of the hindgut

pelvic splanchnic nerve –> parasympathetic innervation of bladder, genetailia, rectum

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5
Q

eyes sympatehtic vs parasympathetic

A

sym- pupil dilation and production of aquous humor

para - pupil constriction

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6
Q

what does the adrenal medulla do

A

secrete adrenaline and noradrenaline in response to sympathetic stimulation from the greater sphlancnic nerve

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7
Q

bladder symp vs para

A

symp - relaxation of destrusor and constriction of urinary sphincter (retention of urine)

para - constriction of detrusor muscle and relaxation of urianry sphincter (release of urine)

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8
Q

symp vs para sexual fucntion

A

para - arousal / erection

symp - orgasm and ejaculation

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9
Q

symp vs para lungs

A

symp - bronchodialtion

para - bronchoconstriction

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10
Q

route parasympathetic to target organ

A

CNS –> long lightly myleinated axon –> AcH bind to nicotinic receptors –> AcH released to stimualte muscarinic receptors on target organ

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11
Q

receptors and neurotrasmitters parasympatehtic nervous system

A

nicotinic and muscarinic receptors

acetylcholine

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12
Q

route most sympatehtic nerve to target organ

A

CNS–> short lightly myelinated axon –> AcH onto nicotinic receptors on sympathteic chian ganglion –> long axon to release noradrenaline onto alpha and beta receptrs on target organ

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13
Q

route sympatehtic to adrenal medulla

A

CNS –> lightly myelinated axon –> AcH onto nicotinic receptors on adrenal medulla –> release of noradrenaline and adrenaline into sympathetic circulation

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14
Q

route sympathetic to sweat glands

A

CNS –> AcH onto nicotinic receptors on sympatehtic chain ganglion –> long axon –> AcH onto muscarinic receptors on sweat glands

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15
Q

what are anticholinergic drugs

A

Antimuscarinic agents operate on the muscarinic acetylcholine receptors. The majority of anticholinergic drugs are antimuscarinics.

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16
Q

what does global vasoconstriction do

A

increases resistance so MAP rises

MAP = CO x resistance

17
Q

difference between norepinephrine and epinephrine in terms of bv and heart

A

norepinephrine = more affect on bv

epinephrine = more affect of heart

18
Q

alpha vs beta adrenergic receptors

A

alpha
smooth muscle contraction
+++ norepinephrine (NO E)
+ epinephrine

beta
smooth muscle relaxation
+++ epinephrine (E)
+ norepinephrine

19
Q

beta 1 vs beta 2 adrenergic

A

beta 1 = heart = 1 heart
beta 2 = lungs = 2 lungs

20
Q

why is norepinephrine used as a vasopressor

A

activates alpha more than beta as norepinephrine
+++ norepinephrine (NO E)
+ epinephrine

21
Q

why is metaraminol used as a vasopressor

A

activates A > B

alpha smooth muscle contraction