AutoImmunity General Information Flashcards
1
Q
CXCL8 recruits what?
A
PMNs
2
Q
CXCL2 recruits what?
A
naive t cells
3
Q
CCL2 recruits what?
A
macrophages
4
Q
IL7 drives growth of what cells?
A
bone marrow cells to make B and T lymphocytes
5
Q
what is the role of CSF?
A
promote production of leukocytes in bone marrow
6
Q
what abs are in type III hypersensitivity?
A
IgG and IgM
7
Q
what is classic finding in type III hypersens?
A
immune complex mediated
8
Q
what is a good example of a type IV hypersens reaction?
A
diabetes type 1
9
Q
what happens in type IV hypersens?
A
CD4 and CD8 cells kill host cells
10
Q
what is positive thymic education?
A
pick for T cells that recognize MHC
11
Q
what is negative thymic education?
A
pick for T cells that do not recognize self peptides
