autoimmune liver disease - mx

Question 1

Which LFTs are elevated?

Answer 1

1. ALT evelated

2. AST elevated

Question 2

Which antibodies are found?

Answer 2

1. Anti nuclear antibodies

2. Anti smooth muscle antibodies

Question 3

How is a diagnosis of AIH made?

Answer 3

1. Positive antibodies

2. Biopsy shows histological finding of AIH.

Question 4

AIH vs PBC?

Answer 4

AIH

1. young adult
2. ALP and AST elevated
3. AMA and ASA antibodies

PBC

1. middle ages
2. ALP and GGT elevated
3. anti mitochondial antibodies

Question 5

How is autoimmune liver disease managed?

Answer 5

1. Prednisolone and azathioprine to induce remission

2. liver transplant

Question 6

Name 2 complication of AIH?

Answer 6

1. liver cirrhosis

2. Hepatocellular carcinoma