Autoimmune Disorders Flashcards
What percentage of RA patients symptoms improve in pregnancy?
80 - 90%
What percentage of RA patients usually relapse post partum and by what time point post partum?
75% relapse within 3 months postartum
What is the effect of RA on pregnancy?
No adverse affects
True or false: It is safe to continue TNF alpha blockers (infliximab, adalumumab ect) in pregnancy
True
What should happen to the infant in a mom treated with TNF alpha blocker
delay rotovirus live vaccine for 6 months following delivery
True or false: Methotrexate should be stopped in pregnancy
True
What is the drug of choice in pregnancy for RA?
Prednisone
How many diagnostic criteria are needed to diagnose lupus erythematosus?
4 criteria
What is the renal protein excretion cutoff required to diagnose lupus?
> 500 mg/24hr urine protein
What are the maternal risks associated with Lupus Nephritis?
Exacerbation, Nephritis, PreEclampsia
What are the fetal risks associated with Lupus?
SAB, IUFD, FGR, PTB, PPROM, Heart block
IUFD with Lupus Erythematosus is strongly associates with what?
Presence of antiphospholipid antibodies
What serologies should be obtained in early pregnancy?
Anti SSA-SSB
What should be done if SSA, SSB positive?
Fetal echocardiogram in the 2nd trimester
How often and when should you start fetal surveillance in a patient with Lupus?
twice weekly starting at 28 weeks