Antiphospholipid syndrome

Question 1

What is the criteria for diagnosis of Antiphospholipid syndrome?

Answer 1

1 lab and 1 clinical criteria

Question 2

What are the clinical criteria for diagnosing APS?

Answer 2

history of vascular thrombosis, Fetal death >10 weeks, severe preE or FGR requiring delivery < 34 wga, > 3 SAB < 10 wks

Question 3

What are the laboratory criteria for diagnosis APS?

Answer 3

Lupus Anticoagulant antigen, Anticardiolipin antibody IgG or IgM, Anti-B2 glycoprotein I IgG or IGM

Question 4

How many tests must you perform to meet laboratory criteria to diagnosis APS?

Answer 4

2 seperate tests 12 weeks apart

Question 5

What are the three main adverse pregnancy outcomes related to APS?

Answer 5

FGR, PreE, Indicated PTD

Question 6

How should you treat APS in pregnancy?

Answer 6

Heparin 5000 U BID + 81 mg aspirin

Question 7

When should you start fetal surveillance with APS?

Answer 7

32wga

Question 8

When should you deliver for uncomplicated APS?

Answer 8

39wga