Autism Spectrum Disorder

Question 1

Adolescent with poor social skills, has difficulty with transitions, rules-focused, spends most free time learning and discussing planets. Diagnosis?

Answer 1

Autism Spectrum Disorder

Question 2

Previously known as childhood psychosis prior to 1960’s?

Answer 2

Autism

Question 3

Small child with ASD, ADHD, and ID on Risperdal and long acting methylphenidate presents to ER with ear infection, becomes agitated and cannot be de-escalated. Best medication for agitation?

Answer 3

Risperdal

Question 4

9 y/o with family history of unexplained syncope wants to start stimulant for ADHD. Next step?

Answer 4

Refer to cardiology for EKG

Question 4

According to diffusion tensor-imaging [DTI], suspected mechanism of action of larger brain size [2-10%] in children with autism by 4 years old is due to?

Answer 4

Overgrowth of long white matter tracts

Question 5

Diagnostic neuroimaging would be indicated in?

Answer 5

10 y/o with autism stops performing previously acquired skills

Question 6

Electroencephalogram useful in initial workup of which psych disorder?

Answer 6

Autism Spectrum Disorder

Question 7

Common speech trait in children with Autism?

Answer 7

Restricted intonation

Question 8

Parents of autistic child wonder about chance of next child having autism?

Answer 8

2-10%

Question 9

Oxytocin as treatment for ASD, fosters what in animal models?

Answer 9

Complex social behaviors

Question 10

Abnormal accelerated white matter maturation found on diffusion tensor imaging in young child?

Answer 10

Autism Spectrum Disorder

Question 11

Brain structural changes in children with autism?

Answer 11

Accelerated increase in brain volume

Question 12

Screen autism spectrum disorder in which genetic condition?

Answer 12

Fragile X Syndrome

Question 13

3 y/o has repetitive rocking when waking up in the morning, head banging while falling asleep at night, less when parents spend time with him, no other concerns except hand flapping when excited. Diagnosis?

Answer 13

Normal development

Question 14

When should you do an EEG for child with Autism?

Answer 14

New onset developmental regression

Question 15

Disorder highly comorbid with sensory integration problems?

Answer 15

Autism

Question 16

13 y/o patient with ASD and developmental delays admitted with catatonia. After 1 week of benzodiazepines with no benefit, next step of therapy?

Answer 16

ECT

Question 17

In ASD, chromosomal microarray analysis is specific for?

Answer 17

DNA duplications or deletions

Question 18

Patient with atypical presentation of autism and no family history. Best technique to identify rare genetic mutations?

Answer 18

Whole-exome sequencing