Anti-NMDA-Receptor Encephalitis

Question 1

Child has Anti-NMDA-Receptor Encephalitis. Pt is anxious, confused, waxy flexibility, minimal verbalization and staring episodes. What is initial treatment for motor symptoms?

Answer 1

Ativan

Question 2

17 y/o has flu-like illness, then psychosis, paranoia, catatonia, and LLQ abdomen mass. Test to order?

Answer 2

Anti-NMDA-Receptor antibodies

Question 3

16 y/o female with memory/confusion issues for 3 weeks, presents w/ new onset agitation, hallucinations, insomnia, inattention, brief seizure, elevated HR/BP, ovarian lesion on ultrasound, otherwise normal exam. Diagnosis?

Answer 3

Anti-N-methyl-d-aspartate receptor encephalitis

Question 4

Adolescent admitted for paranoia, hallucinations, mood lability, then develops facial tics, autonomic instability, obtunded. Adnexal mass on workup. Removal likley to normalize activity of receptor for which neurotransmitter?

Answer 4

Glutamate