Autism Spectrum Disorder Flashcards

1
Q

What is autism spectrum disorder (ASD)?

A

It is defined as a neurodevelopmental condition characterised by abnormal social interaction, communication and restricted, repetitive behaviours

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2
Q

Describe the autism spectrum

A

The DSM-5 criteria combined autism disorder and Asperger’s syndrome into autism disorder, suggesting that the same disorder was responsible for the features of the condition and those affected fall somewhere along the spectrum

On one end of the spectrum, individuals have normal intelligence and ability to function everyday life however display difficulties with reading emotions and responding to others – previously known as Asperger’s syndrome. On the other end of the spectrum, individuals can be severely affected and unable to function in normal environments – previously known as autism disorder

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3
Q

What are the eight risk factors assoicated with autism spectrum disorder?

A

Male Gender

Family History

Attention Deficit Hyperactive Disorder

Epilepsy

Infantile Spasms

Congenital Rubella

Tuberous Sclerosis

Fragile X Syndrome

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4
Q

What are the three genes associated with autism spectrum disorder?

A

PTEN gene

MeCP gene

CNV gene

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5
Q

At what age do autism clincial features tend to be evident?

A

3 years old

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6
Q

What are the three main clincial features of autism spectrum disorder?

A

Impaired Social Interaction

Impaired Communication

Restricted, Repetitive Behaviour

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7
Q

What are the four clincial features of impaired social interaction in autism spectrum disorder?

A

Inability To Form Social Attachments

Inability To Interpret Social Cues

Lack of Response To Other People’s Emotions

Uninterested In Being With Other Children

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8
Q

What are the three clinical features of impaired communication in autism spectrum disorder?

A

Delayed Language Development

Lack of Non-Verbal Communication

Repetitive Use of Words & Phrases

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9
Q

What are the six clincial features of restricted, repetitive behaviour in autism spectrum disorder?

A

Stereotyped, Repetitive Movements

Resistance To Change With A Rigid Daily Routine

Anxiety With Experiences Outside Their Normal Routine

Inability To Adapt To New Environments

Intensive Interests In Objects, Numbers or Patterns

Restricted Food Preferences

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10
Q

How is a diagnosis of autism spectrum disorder obtained?

A

A clinical assessment should be conducted by a paediatric psychiatrist

There should be evidence of deficits occurring across all three aforementioned domains: social interaction, communication and behaviour

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11
Q

What are the two diagnostic tools used to diagnose autism spectrum disorder?

A

Diagnostic Interview for Social & Communication Disorders (DISCO)

Autism Diagnostic Observation Schedule (ADOS)

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12
Q

What are the five aims of autism spectrum disorder management?

A

To increase functional independence and quality of life through…

  • Supported learning and development
  • Improved social skills
  • Improved communication skills
  • Decreased disability and comorbidity
  • Support to families
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13
Q

What are the five non-pharmacological management options of autism spectrum disorder?

A

Specialist Education Services

Occupational Therapy

Speech Therapy

Clinical Psychology

Family Counselling

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14
Q

What are the three pharmacological management options of autism spectrum disorder?

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Antipsychotic Drugs

Melatonin

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15
Q

Name four SSRIs used to manage autism spectrum disorder

A

Sertraline

Fluoxetine

Citalopram

Paroxetine

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16
Q

When are SSRIs used to manage autism spectrum disorder?

A

They can be used to reduce stereotyped, repetitive behaviour, anxiety and aggression

17
Q

Name four antipsychotic drugs used to manage autism spectrum disorder

A

Olanzapine

Risperidone

Quetiapine

Aripiprazole

18
Q

When are antipsychotic drugs used to manage autism spectrum disorder?

A

They can be used to reduce aggression and self-injury

19
Q

When is melatonin used to manage autism spectrum disorder?

A

It can be used to manage sleep difficulties, in cases where behavioural management and sleep hygiene have proven to be unsuccessful