Auditory and Vestibular System Flashcards
What makes up the outer ear?
- pina
- external auditory meatus
What makes up the middle ear?
- malleus
- incus
- stapes
- eustachian tube
What makes up the inner ear?
- the vestibule
- the semicircular canals
- the cochlea.
What is the function of the inner ear?
transduction
What is Transduction?
conversion of one energy form to another
mechanical sound waves to electrical signals
What term is used to describe the arrangement of the basilar membrane?
- tonotopic arrangement
- high to low frequency from base to apex
high frequency: tight and narrow
What is the auditory pathways to the brain?
- cochlear nucleus
- superior olive (bilateral)
- inferior colliculus
- medial geniculate body
auditory cortex
How does the middle ear amplify sound?
- focuses vibrations from large SA (tympanic membrane) to small SA (oval widow), increasing pressure
- leverage from the incus -stapes to increase the force on the oval window
- malleus, incus and stapes articulate to facilitate the transmission of sound into the inner ear
What are the three ossicles?
- malleus
- incus
- stapes
How does the inner ear transduce sound?
- deflection of the stereocilia towards the longest cilium opens potassium ion channels within the inner hair cell, as the tectorial membrane makes contact
- ionic interchange of potassium within the endolymph and inner hair ells causing cell depolarisation
- inducing the opening of voltage-gated calcium channels releasing excitatory neurotransmitters (glutamate) onto the afferent nerve
What are the three scala/compartments of the cochlear?
- scala vestibuli
- scala tympani
- scala media
How can we categorise causes of hearing loss?
- sensorinueral
- conductive
What is conductive hearing loss?
- dissociation between air and bone conduction
(bone is maintained, greater threshold required for air conduction) - middle or outer ear affected
- hair cells are functional when stimulated within the inner ear
What is sensorineural hearing loss?
- both air and bone conduction are affected similarly
- problem with the inner ear of vestibulocochlear nerve problem
- sound is unable to be effectively transduced to the auditory cortex
What are possible causes of conductive hearing loss?
outer ear: - wax and foreign bodies middle ear: - otitis externa/media - otosclerosis (stuck stapes)
What are causes of sensorineural hearing loss?
inner ear: - presbycusis - ototoxicity (loss of hair cells) nerve: - VIII nerve tumour (acoustic neuroma)
What are the main 2 tuning fork tests?
- Rinne test
- Weber test
What are the 3 main inputs of the Vestibular system?
- visual
- proprioceptive
- vestibular information
What are the outputs of the Vestibular system?
reflexes to maintain a stable posture and stable gaze
- ocular (maintains fixed image upon movement)
- postural reflex (ensures individuals maintain composure)
What structure within the inner ear is anterior?
The cochlea concerned with auditory input.
What structure within the inner ear is posterior?
Labyrinth concerned with the vestibular system. The bony labyrinth resides within the petrous part of the temporal bone.
What is part of the vestibular organ?
- utricle and saccule (in the vestibule), joined by a conduit.
- Saccule is connected to the cochlea.
- Three semi-circular canals (Anterior, posterior and lateral) in each ear.
- with an ampulla on each side, connected to the utricle.
- Canals contain endolymph fluid.
What angles are the semi-circular canals at?
- the anterior and posterior semi-circular canal form a 90-degree angle
- the anterior canal is 45 degrees to the front
Describe the structure of vestibular hair cells?
- kinocilium (largest cilium)
- stereocilia
What is the role of the stereocilia on the hair cells?
- orientated to a particular side
- deflection induces cellular depolarisation in response to endolymph movement
What are the otolith organs?
- utricle
- saccule
What is the maculae made up of?
- hair cells
- gelatinous matrix (otolith crystals)
- hair cells are horizontal in the utricle
- hair cells are vertical in the saccule
What is in the ampulla?
- crista (hair cells)
- cupula which facilitates hair cell movement
What does endolymph contain?
high concentration of K+
What should NOT be present in the semi-circular canals?
otoliths
Where does the vestibular nerve form nuclei?
- Oculomotor nucleus
- Trochlear nucleus
- Medial longitudinal fasciculus
- Abducens nucleus
- Vestibular nuclei (Main generator of reflex.)
- Vestibular ganglion
- Vestibulospinal tract
What does the vestibular nuclei have projections to?
- spinal cord
- nuclei of the extraocular muscles
- cerebellum
- centres of cardiovascular and respiratory control
Where does the primary afferents of the vestibular nerve end?
- vestibular nuclei
- cerebellum
Where are the main processing centres of the vestibular cortex?
in the parieto-insular vestibular cortex (parietal lobe)
What is responsible for processing in the vestibular system?
- main: vestibular nuclear complex
- adaptive: cerebellum
What is the function of the vestibular system?
- detect and inform about head movements
- postural control
- keep images fixed in the retina during head movements
What happens with the stereocilia move towards the kinocilium?
- depolarisation
- increasing nerve discharge
- excitation
What happens with the stereocilia move away from the kinocilium?
- hyperpolarisation
- reduced nerve discharge
Describe the relationship between the hair cell potentials in the left and right ear?
- antagonistic
- excitation and inhibition occur simultaneously at that specific velocity
What are the 2 different vestibular reflexes?
- vestibulo-ocular reflex
- vestibulo-spinal reflex
What happens in the vestibulo-ocular reflex?
- eye movement in opposite direction to head movement (same velocity and amplitude)
- involves the vestibular nuclei and oculomotor nuclei
Why does the vestibulo-ocular reflex occur?
to ensure images remain fixed in the retina
What happens in the vestibulo-spinal reflex?
- motor neurones to the neck and back muscles (medial tract)
- postural control, compensatory body movement according to head position
How do you assess the vestibular system?
- anamnesis (Hx)
- posture and gait (posturography)
- cerebellar function (CT and MRI)
- eye movements
What tests can be done to test the vestibular system?
- caloric test
- video head impulse test
- vestibular evoked myogenic potential
- rotational test