Attention and learning disorders Flashcards

1
Q

DDx attention difficulties

A
ADHD
learning, developmental disability
stressors
sensory abnormalities
psychiatric/emotional
immaturity
prenatal substance exposure
hunger
sleep disturbance/disorders
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2
Q

ADHD

A

“Developmental impairment in the brain’s executive functions”
centred in prefrontal cortex with other region involvement
- develops in early childhood through to adulthood

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3
Q

DSM5 for ADHD

A

A. persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development, characterised by (1)inattention or (2)hyperactivity-impulsivity
B. Several hyperactive-impulsive or inattentive symptoms causing impairment present before 12 y
C. Several impairments from the symptoms is present in >=2 settings
D. Clear evidence that symptoms interfere with functioning
E. do not occur exclusively during the course of a Pervasive developmental disroder, schizophrenia/psychotic disorder, not better accounted for by another mental disorder

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4
Q

DSM5 ADHD Inattention criteria

A

> =6 for >=6 mo that is inconsistent with developmental level and negatively impacts social/academic/occupational activities

  1. often fails to give close attention to details, make careless mistakes
  2. difficulty sustaining attention in tasks/play
  3. does not seem to listen when spoken to directly
  4. does not follow through on instructions, fails to finish duties/work
  5. difficulty organizing tasks and activities
  6. often avoids/dislikes/reluctant to engage in tasks that require sustained mental effort
  7. often loses things necessary for tasks or activities
  8. often easily distracted
  9. often forgetful in daily activities
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5
Q

DSM5 ADHD hyperactivity-impulsivity criteria

A

> =6 for >=6 mo that is inconsistent with development, and negatively impacts social/academic/occupational activities
Hyperactivity
- fidgets with hands, feet, squirms
- leaves seat in classroom when expected to remain seated
- runs about/climbs excessively when inappropriate
- often has difficulty playing or engaging in leisure activities quietly
- “on the go” or acts as if driven by a motor
- talks excessively

Impulsivity

  • blurts out answers before questions are completed
  • difficulty awaiting turn
  • interrupts/intrudes on others
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6
Q

types of ADHD in DSM5

A

ADHD combine presentation if both inattention/hyperactive impulsivity identified in the past 6 mo
ADHD predominantly inattentive presentation
ADHD predominantly hyperactive-impulsive presentation
Specify if in partial remission
Specify current severity (mild, moderate, severe)

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7
Q

Prevalence of ADHD

A
commonly diagnosed
varies from country to country
8-15% of North American children
Children on Medicaid: 14%
incidence increasing over last decade
Male: female 3:1
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8
Q

Proposed etiologies of ADHD

A

not proven
Genetic: increased incidence in family esp in father
- increased incidence of conduct disorders, learning disabilities, ADHD in siblings
- specific variant of genes identified but no consistent results
- 1 parent with ADHD: may have as high as 50% chance of having ADHD

Neurochemical pathways
- Low dopamine
-NE? (affects attention and alertness)
Serotonin?

Environmental injury - insults, traumatic brain injury, toxins, developmental lag

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9
Q

Pathophysiology of ADHD

A

neuroanatomical differences on MRI
small decreases in size of certain brain areas
loss of normal asymmetry
no consistent findings
functional imaging studies implicate prefrontal cortex, anterior cingulate and striatum

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10
Q

Phase I Tx of ADHD

A
education for parent, child and teacher
psychological support
behavioural modification/management
lifestyle
mindfulness exercises
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11
Q

Phase II Tx of ADHD

A

medical therapy - stimulant

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12
Q

Long term outcomes of ADHD

A

significant persistence into young adulthood, esp in children from low SES
can remit in childhood/early adolescence
family adversity increases risk of persistence
no long term outcome studies confirming that treatment with medication changes functional outcome

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13
Q

Specific learning disorders

A

DSM5: specific deficits in an individual’s ability to perceive/process information efficiently and accurately
Difficulties in learning reading and/or writing and/or math
performance well below what would be predicted for age or acceptable performance or is only achieved with extraordinary effort
NO intellectual disability
discrepancy model - discrepancy between intellectual ability and achievement (Ministry of Education)

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14
Q

Learning disability prevalence

A

BC: 3% of children with severe learning disability based on statistical differences in test scores
actual # probably 10%
common, tend to co-occur with ADHD

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15
Q

Dx of learning disabilities

A

need a full psychoeducational assessment
strong suspicion clinically
can’t complete cognitive testing until child is at least 4.5
can’t get accurate information about achievement until child is in school

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16
Q

Consider LD in these children:

A
behavioural problems
diagnosed with ADHD
isn't achieving in school
speech/language delay
family history of LD
delayed in learning alphabets/numbers
17
Q

Office screening for learning disabilities

A

language tasks: following directions, reading
non-verbal tasks: memory game, puzzles
school achievement: reading samples, math, writing, drawing a picture

18
Q

LD interventions

A
Multimodal teaching strategies
individualized education plans
specialized schools - \$\$$ but effective
recreation
parents
think ahead to vocational/career planning
19
Q

FASD prevalence

A

common: at least 1/100
expensive: 1.5 mil/child lifetime
devastating
preventable

20
Q

FASD

A

lifelong condition characterized by abnormalities in growth, face, brain
increased dose, more severe effects

21
Q

Growth deficiency in FASD

A

low birth weight if drinking in late pregnancy
postnatally less than adequate weight gain despite adequate caloric intake
disproportionately low weight compared to height

22
Q

FASD facial presentation

A

short palpebral fissures
flattened philtrum
thin upper lip

23
Q

Functional impairments in FASD

A

often invisible
most common diagnosable cause of intellectual handicap, but majority have normal to just below avg intelligence
85% adults with FASD cannot live independently due to weak adaptive skills and poor exectuvei functions

24
Q

Possible mechanisms of teratogenesis of alcohol

A

increased cell death and reduced neural crest cell numbers (apoptosis): FAS craniofacial features
oxidative stress
accumulation of fatty acid ethylesters
stress and hormonal mediation
effects on serotonin: important NT with neurotrophic effects
NMDA receptor
Epigenetic effects of perinatal stress, maternal emotional stress, neglect, poor nutrition