ATP pumps Flashcards

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1
Q

what is ATP?

A

adenosine triphosphate - source of energy for cells

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2
Q

what is indirect active transport?

A

coupled transport where ions (protons) power the transport of solute

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3
Q

what is direct active transport?

A

using ATP to directly pump solute against gradient

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4
Q

what does amino acid absorption (transportation) require?

A

both indirect (amino acid symporters move amino acids into enterocytes) and direct (ATPase pumps maintain ion gradients)

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5
Q

what are the four types of ATPases?

A

P-ATPases
vacuolar-ATPase
F-type ATPases
ABC-type ATPases

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6
Q

what are P-ATPases regulated by?

A

phosphorylation

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7
Q

what are the types of P-ATPases?

A

P1 - transport heavy metals
P2 - maintain electrochemical gradients
P3 - membrane potential plants and fungi
P4 - flippase, moves phospholipids
P5 - unknown function

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8
Q

what are three P2-ATPases?

A

Ca 2+ and H+ (keeps Ca 2+ low in cytosol)
Na+ and K+ (maintains membrane potential)
H+ and K+ (pumps H+ to acidify stomach)

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9
Q

what is vacuolarATPase?

A

two rotary motors, where ATP driven motor turns another motor that pumps protons
pumps H+ ions to increase acidity in organelles
regulated by separating the motors

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10
Q

what are F-type ATPases?

A

ATP synthases that move ions with the concentration gradient to produce ATP in the mitochondrial inner membrane

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11
Q

what are ABC-type ATPases?

A

contain ATP-binding cassettes with two conformational states that mediate ATP-powered translocation of many substrates

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