ATP pumps Flashcards
what is ATP?
adenosine triphosphate - source of energy for cells
what is indirect active transport?
coupled transport where ions (protons) power the transport of solute
what is direct active transport?
using ATP to directly pump solute against gradient
what does amino acid absorption (transportation) require?
both indirect (amino acid symporters move amino acids into enterocytes) and direct (ATPase pumps maintain ion gradients)
what are the four types of ATPases?
P-ATPases
vacuolar-ATPase
F-type ATPases
ABC-type ATPases
what are P-ATPases regulated by?
phosphorylation
what are the types of P-ATPases?
P1 - transport heavy metals
P2 - maintain electrochemical gradients
P3 - membrane potential plants and fungi
P4 - flippase, moves phospholipids
P5 - unknown function
what are three P2-ATPases?
Ca 2+ and H+ (keeps Ca 2+ low in cytosol)
Na+ and K+ (maintains membrane potential)
H+ and K+ (pumps H+ to acidify stomach)
what is vacuolarATPase?
two rotary motors, where ATP driven motor turns another motor that pumps protons
pumps H+ ions to increase acidity in organelles
regulated by separating the motors
what are F-type ATPases?
ATP synthases that move ions with the concentration gradient to produce ATP in the mitochondrial inner membrane
what are ABC-type ATPases?
contain ATP-binding cassettes with two conformational states that mediate ATP-powered translocation of many substrates