ATP Flashcards

1
Q

the energy required to reduced CO is proivded by the

A

absorption of protons (which are reraised to a higher energy state)

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2
Q

from photosynthesis throuhout carbohydrate metaoblism energy isn’t changed by

A

flows

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3
Q

Energy stored in ___ is converted to energy stored in ATP

A

reduced fuels

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4
Q

ATP drives work function returning energy to the environment as____

A

heat (IR photons)

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5
Q

Life disorders its surroundings more or it orders itself by disordering light energy?

A

disorders its surrounding more

we use this to order ourselves

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6
Q

phosphoate bonds on atp are named

A

alpha, beta, gamma going in (closest to sugar) to outward

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7
Q

two energy rich bounds in atp?

A

in the phopshoandhryride bonds ( between gamma and beta, beta and alpha)

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8
Q

reasons why the phosphoandrhydrides bonds are energy rich (3)

A
  1. there is charge repulsion that is releived upon breaking the α-β or β-γ bonds
  2. greater resonance stabilization of products after you break ADP + Pi or AMP + PPi
  3. produces have more favorable interaction with water
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9
Q

ATP directly or indirectly drives 3 main work functions

A
  1. mehcnaical work
  2. tranport work
  3. biosynthetic work
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10
Q

___ meets our immediate energy needs

A

ATP

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11
Q

___ can meet our long term needs

A

fats and protein

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12
Q

Why is ATP well suited for its role as energy carrier? (4)

A
  • Number of ~P (i.e., 2)
  • Soluble and mobile
  • High affinity binding to enzymes
  • Recognition handle (has the right bases for enzymes to bind)
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13
Q

The height of the energy barrier, ___ determines the rate of reaction

A

ΔG‡ (also “Ea”),

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14
Q

All important biological molecules are at local energy ____

A

minima

this allows the body to control the use of these molecules

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15
Q

Cells control reactions by producing____ that allow
biological molecules to escape from energy minima

A

regulated catalysts (enzymes)

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16
Q

Enzymes change the reaction___ and ____of the energy barrier (ΔG‡).

A

path and lower the height

17
Q

enzymes do not change ___

A

ΔG°ʹ′

18
Q

why atp not adp?

A

sometimes cleaveage of one P bond is not enough

adp bound bind too weakly to enzymes

different bases are located on adp (recognition handl)

19
Q

An intermediate thermodynamic value is consistent with ATP’s role as an___ and a ____

what couples such reactions?

A

acceptor and a donor

20
Q

with the common intermediate principle

The total ΔG°ʹ′ for the two reactions is ____ by the enzyme

A

not altered

21
Q

The exergonic reaction (ADP + Pi –> ATP ) is obligatorily coupled to the endergonic reaction (ATP
synthesis) by

A

E-P, a common intermediate in both reactions

22
Q

conversion of ATP to the different NTPs is ____.

A

reversible

23
Q

Why a Central Pool of Energy?

Due to the presence of nucleoside diphosphate kinase (NDK), the various NTP pools are able to (2)

A

share available energy and avoid rate-limiting steps (e.g. fleeing a predator).

24
Q

Why a Central Pool of Energy?

the levels of ___ (4) reflect the cell energy state

A

ATP, ADP, AMP, and Pi

25
Regulatory enzymes have evolved regulatory binding sites. Some of these sites are able to sense the energy state of the cell by binding \_\_\_
adenine nucleotides.
26
ATP-generating pathways are inhibited by high levels of \_\_? stimulated by \_\_\_?
inhibited by high ATP stimulated with high levels of ADP and/orAMP
27
ATP-utilizing pathways are inhibited by high levels of \_\_? ## Footnote stimulated by \_\_\_?
inhbiited by high levels of ADP and/or AMP stimulated by high levels of ATP
28
The regulatory enzyme which turns a pathway on and off in response to the energy state of the cell usually catalyzes an _____ step in the pathway.
early step (feedback inhibition)
29
Vertebrate muscle and nerve (creatine kinase):
30
Adenylate kinase (ubiquitous)
31
adenylate deaminase (liver and skeletal muscle)
32
enzyme involved?
creatine kinase
33
enzyme involved?
Adenylate kinase (ubiquitous)
34
adentylate deaminase
35
ATP buffers include
1. phosphagens (allow muscles to last longer and stronger) 2. adenylate kinase (many cells, not just muscles) 3. adenylate deaminase (liver and skeltal muscle) -- pulls adenylate kinase rxn forward
36