atherosclerosis Flashcards
what is atherosclerosis
an arterial disease characterized by thickening or hardening of the arteries
what is the leading cause of heart and stroke
atherosclerosis
what is sufficient for the development of artherosclerosis
increased serum cholesterol
normal artery wall consist of what
intima
media
adventitia layer
the intima consist of
endothetial
subendothelial marix
basement membrane intima
facts about the media
middle and thickest
has smooth muscle cells
provides vascular tone
facts about the adventitia layer
consist of
collagen fibers
vasovasorums
nerve endings
has sparse cell distribution
Some pathophysiology
deposition of lipoproteins
platlet adhesion
lipid accumulation
what is the atherommatous plaque
white or yellow lesions that
are elevated from the vessel intima, but may coalesce to form larger
masses
what is an ulcerted plaque
take on a red-brown color due to thrombus
accumulating on the plaques
what is the most sensitive method to diagnose atheroosclerosis
angiography or Doppler ultrasound
if an atherosclerosis involves the carotid artery it can cause what
stroke
if it involves the coronary artery it can cause
ischemic heart disease or arrythmia
if it involves renal arteries it can cause
kidney disease
plaque rupture occurs as what
clinically trigerring of thrombus formation