Astrovirus Flashcards
1
Q
Astrovirus structure & classification
A
Family: Astroviridae
Genus: Avasteovirus & Mamastrovirus
(+)ss RNA NON ENVELOPED
2 human clades
2
Q
Astrovirus clinical syndromes
A
Acute diarrhoea
Extra-GI in immunocompromised- meningitis & encephalitis
3
Q
Astrovirus diagnostics
A
RT-PCR & typing offered by enteric virus unit (EVU) UKHSA Colindale
Biofire GI panel
4
Q
Astrovirus therapeutics
A
Nitazoxanide & Ribavirin - unclear benefit