Astrovirus Flashcards

1
Q

Astrovirus structure & classification

A

Family: Astroviridae
Genus: Avasteovirus & Mamastrovirus

(+)ss RNA NON ENVELOPED

2 human clades

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2
Q

Astrovirus clinical syndromes

A

Acute diarrhoea

Extra-GI in immunocompromised- meningitis & encephalitis

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3
Q

Astrovirus diagnostics

A

RT-PCR & typing offered by enteric virus unit (EVU) UKHSA Colindale

Biofire GI panel

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4
Q

Astrovirus therapeutics

A

Nitazoxanide & Ribavirin - unclear benefit

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