Asthma/PE PBL Flashcards
S1Q3T3
I: large S-wave
III: large Q-wave, inverted T-wave
indicative of PE
not sensitive or specific
Patient education gives patient
sense of self-efficacy
Beteyko technique
reduce hyperventiation
Papworth method
integrated breathing and relaxation techniques
Aspirin-exacerbated asthma
pathology
decreased baseline COX activity
increased leukotriene synthesis
ASA and NSAIDs exacerbate
D-dimers
sensitivity
specificity
sens: 97.5%
spec: 66.9%
Warfain after DVT
3 mo if provoked
>3 mo if unprovoked
Long-term anti-coag
cancer vs no cancer
cancer: LMWH > warfarin
non-cancer: warfain > LMWH
Thrombolysis in PE
catheter-locally delivered
Corticosteroids
MOA
GRE (glucocorticoid response element)
transcriptional regulation
induces lipocortin to inhibit PLA2
no release of AA
inhibits NF-kB
decreased TNF-α, IFN-γ, IL-1, IL-2
Steroids and β2 agonists
synergy
steroids increase expression of β2 receptors