Asthma Flashcards
What causes asthma attack?
chronically hyperactive and inflamed airways leading to airflow obstructin
symptoms of asthma
wheezing, coughing, dyspnea, chest tightness, chest pain
Components of managment
- routine monitoring of symptoms/lung function
- create partnership
- control environmental factors, comorbid conditions
- pharm therapy
Goals of treatment
- decrease frequency of symptoms
- minimal need of SABA
- fewer night-time awakening
- optimization of lung function
- maintenance of normal daily activities
Categories of severity
- Intermittent
- Mild, persistent
- Moderate, persistent
- Severe, persistent
Intermittent Asthma
- daytime asthma symptoms occurring 2 or less days per week
2. 2 or less nocturnal awakenings per month
Mild, persistent Asthma
- symptoms more then 2x weekly (but less than daily)
2. ~3-4 nocturnal awakenings per month (but fewer than every week)
Moderate persistent
- daily symptoms
2. nocturnal awakenings at least once a week
Severe persistent
- symptoms throughout day
2. nocturnal awakenings nightly
Treatment of Intermittent
Quick acting inhaled beta-2 selective adrenergic agonist PRN
Treatment of mild persistent
Daily long-term controller medication: low dose inhaled glucocorticoid + SABA
Alternative for step 2 (low dose inhaled GC)
leukotriene receptor antagonists
Treatment of moderate persistent
- Low dose inhaled GC + inhaled LABA
OR - medium dose inhaled GC
Treatment of persistent asthma
- medium or high dose of inhaled GC and LABA
2. Can add leukotriene modifier (triple-controller therapy)
What can you give if evidence of sensitivity to perennial allergen and inadequately controlled on high-dose inhaled GCs and LABAs
omalizumab
