Assessment Of Bioavailability Flashcards by Лили Ауси

Q

What is the most commonly used method of assessing the bioavailability of a drug

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Q

Explain the plasma concentration time curve until it reaches Cmax

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Q

Explain the ascending part of the graph

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Q

Explain the descending portion of the graph

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Q

Explain the elimination phase of the graph

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Q

Define onset

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Q

Define duration

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Q

Define peak concentration

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Q

Define time to peak concentration

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Q

Define the Area under the plasma concentration time curve

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Q

What are the factors that can complicate the interpretation of bioavailability studies

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Q

Explain the cumulative urinary drug excretion curves

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Q

What are the limitations of cumulative urinary drug excretion curves

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Q

Define the absolute bioavailability

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Q

How can absolute bioavailability be calculated

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Q

Define relative bioavailability

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Q

What is bioequivalance

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Q

How is bioequivalence assessed

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Q

Why is bioequivalence important

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Q

What are the types of equivalency

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Pharmaceutical equivalence
Pharmaceutical alternatives
Bioequivalent drug products
Therapeutic equivalence

Q

Define pharmaceutical equivalence

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Q

Explain the key conditions of pharmaceutical equivalence

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Q

Give an example of pharmaceutical equivalence

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Q

Define pharmaceutical alternatives

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Q

What are the key differences of pharmaceutical alternatives

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Q

Give example of pharmaceutical alternatives

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Q

Define bioequivalent drug products

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Q

Explain the key criteria for bioequivalent drug products

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Q

Give example of bioequivalent drug products

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Q

Define therapeutic equivalence

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Q

Explain the key criteria of therapeutic equivalence

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Q

Give example of therapeutic equivalence

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Q

What is the BCS

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