Absirption From Different Sites Of Administration Part 3 Flashcards
Topical application includes what
Mucus membranes
Eye
Skin
Rectal route
Exp,son mucus membrane drug delivery
Explain eye drug delivery system
Topical drug delivery is generally used for…
Local drug effects at the site of application
In skin application dosing is dependent on what
Is there systemic absorption through the skin
Drug absorption via the skin is enhanced if the drug substance is…
Absorption of drugs able to penetrate the intact skin is dependent on what
Surface area over which they are applied and their lipid solubility
Systemic absorption occurs through what
Burned or damaged skin
Toxic effects may result from
Absorption through the skin can be enhanced by what
Drugs that are absorbed enter the skin by what
How does topical application on the skin reach general circulation
What is used to facilitate absorption in skin drug delivery
Hydration of the skin with an occlusive dressing
What affects drug penetration rate
The thickness of the skin that varies across the different areas of the body
Example of transdermal absorption
Transdermal products are generally used for…
Systemic drug absorption
For transdermal drug delivery the drug is…
Incorporated into a transdermal therapeutic system or patch, but it may be incorporated into an ointment as well
What are the advantageous of transdermal absorption
Rectal route can be used for…
Local and systemic effects
Explain what could the rectal route be used for
What is the disadvantage of rectal route
What are the factors affecting drug absorption after the rectal administration
